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New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology, an Official Journal of the American Urological Association.

17 Apr 2024

Exploring the versatile roles of tissue macrophages beyond immune defense

The role of resident tissue macrophages (RTMs) in homeostasis and disease.

17 Apr 2024

Research unveils bispecific antibodies for B-cell lymphoma treatment

A new research paper was published in Oncotarget's Volume 15 on April 12, 2024, entitled, "Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface."

16 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Genetically engineering skin bacteria to fight cancer

While studying a type of bacteria that lives on the healthy skin of every human being, researchers from Stanford Medicine and a colleague may have stumbled on a powerful new way to fight cancer.

15 Apr 2024

New genetic variants could raise a woman's risk of cervical cancer from HPV infections

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.

12 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Three-step prostate cancer screening method demonstrates reduced overdiagnosis

A large randomized trial conducted at Tampere University and the University of Helsinki shows that a new three-step prostate cancer screening method can find a considerable number of aggressive cancers.

10 Apr 2024

Researchers identify the most harmful modifiable risk factors for dementia

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

10 Apr 2024

Educational video boosts prostate cancer screening intentions in men

As part of a comprehensive effort to improve cancer screenings among diverse communities, Penn Medicine's Abramson Cancer Center (ACC) Community Outreach and Engagement team developed a culturally sensitive educational video to address prostate cancer screening disparities.

10 Apr 2024

Study reveals inflammation's role in long COVID's lingering effects

Large-scale study found that long COVID patients exhibit sustained inflammation and specific immune responses associated with varying symptoms, highlighting the importance of personalized treatment approaches.

9 Apr 2024

Researchers find new clues to understanding the progression of primary membranous nephropathy

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood.

9 Apr 2024

Blood test every five years could revolutionize prostate cancer screening

A simple blood test every five years is sufficient to screen low risk men for prostate cancer, new research has shown.

5 Apr 2024

Gold nanoparticle adorned polymers boost infectious disease testing

By harnessing the power of composite polymer particles adorned with gold nanoparticles, a group of researchers have delivered a more accurate means of testing for infectious diseases.

5 Apr 2024

Lancet Commission predicts sharp increase in global prostate cancer cases

Cases of prostate cancer are projected to double from 1.4 million per year in 2020 to 2.9 million per year by 2040, with low- and middle-income countries (LMICs) predicted to see the highest increases in cases, according to The Lancet Commission on prostate cancer which will be launched by a presentation at the European Association of Urology Congress.

4 Apr 2024

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.

1 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024