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Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Pluripotent stem cells (PSCs) are a type of stem cells capable of developing into various cell types. Over the past few decades, scientists have been working towards the development of therapies using PSCs.

30 May 2024

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells.

30 May 2024

Decoding the function of SRSF1 protein in RNA splicing and translation regulation

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence.

30 May 2024

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Researchers decode spatial structure of prime editor

Joint research led by Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo determined the spatial structure of various processes of a novel gene-editing tool called "prime editor."

29 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.

24 May 2024

UCLA research connects genetic risk and brain changes in autism

A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.

23 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Harnessing molecular pathways governed by key gene to enhance wheat yields

A study from the University of Adelaide has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

23 May 2024

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, the conventional delivery methods have several limitations.

20 May 2024

Non-viral gene therapy offers hope for chronic low back pain sufferers

A novel non-viral gene therapy for discogenic back pain (DBP).

20 May 2024

Diet and nutrition's influence on acne vulgaris

Study highlights the significant role of certain dietary components, such as dairy, chocolate, and fats, in the development of acne vulgaris and underscores the need for further research to inform effective dietary recommendations.

19 May 2024

H5N1 avian flu strain jumps to seals in Quebec, raising zoonotic fears

Study describes the unusual mortality of gray and harbor seals in Quebec due to a highly pathogenic avian influenza A (H5N1) strain, raising concerns about potential zoonotic spillover.

17 May 2024

TRPS1 could serve as a new target for drugs against breast cancer

The mammary gland is a complex tissue comprising a variety of cell types. Their proper functioning is crucial for the health of the breast.

16 May 2024

Investigating age-associated gene expression changes in mouse sweat glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

The adipose-neural axis plays an important role in arrhythmogenesis.

15 May 2024

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

A study in Cell Reports Medicine used an in vitro co-culture of adipocytes, cardiomyocytes, and sympathetic neurons to reveal that the adipose-neural axis plays a crucial role in arrhythmogenesis, driven by interactions between epicardial adipose tissue and the sympathetic nervous system.

14 May 2024

Transcription News and Research

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Decoding the function of SRSF1 protein in RNA splicing and translation regulation

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Newly discovered lincRNA controls the development and function of regulatory T cells

Researchers decode spatial structure of prime editor

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Two new studies offer insights into the molecular biology of neuropsychiatric disease

UCLA research connects genetic risk and brain changes in autism

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Harnessing molecular pathways governed by key gene to enhance wheat yields

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

Non-viral gene therapy offers hope for chronic low back pain sufferers

Diet and nutrition's influence on acne vulgaris

H5N1 avian flu strain jumps to seals in Quebec, raising zoonotic fears

TRPS1 could serve as a new target for drugs against breast cancer

Investigating age-associated gene expression changes in mouse sweat glands

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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