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Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

Glioblastoma multiforme (GBM) is among the most aggressive forms of brain tumors, with few effective treatment options and a bleak prognosis.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries.

12 Jun 2024

The unregulated sale of Amanita muscaria mushrooms needs a public health response

The legal status, safety, and availability of Amanita muscaria.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Short-term adverse effects of COVID-19 mRNA vaccinations are linked to higher and longer-lasting neutralizing antibody responses, indicating robust immune efficacy.

11 Jun 2024

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Sepsis – the leading cause of mortality in children around the world – can present with a wide range of signs and symptoms, making a one-size-fits-all treatment strategy ineffective.

11 Jun 2024

Attenuated virus helps eliminate cancer in mice

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice.

11 Jun 2024

High-flow oxygen technique equally safe as traditional anesthesia in pediatric tubeless airway surgery

A new high-flow oxygen technique is as safe as standard anesthetic methods during tubeless upper airway surgery in children, according to University of Queensland research.

11 Jun 2024

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

A novel AI approach can accurately detect six different types of cancer on whole-body PET/CT scans, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

11 Jun 2024

Microgravity and galactic radiation: Dual threats to astronaut kidney health

The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardize any mission to Mars, according to a new study led by researchers from UCL.

11 Jun 2024

Study reveals limitations of cognitive tests in diagnosing concussions among college athletes

When college athletes are evaluated for a possible concussion, the diagnosis is based on an athletic trainer or team physician's assessment of three things: the player's symptoms, physical balance and cognitive skills.

11 Jun 2024

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Systematic reviews of medical literature between 2020 to 2024 show bariatric surgery, also known as metabolic or weight-loss surgery, produces the greatest and most sustained weight loss compared to GLP-1 receptor agonists and lifestyle interventions.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

Medicine News and Research

Enhancing CAR-T cell therapy with biodegradable scaffolds

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

The unregulated sale of Amanita muscaria mushrooms needs a public health response

UD researchers pioneer universal, economical method for proteomics sample preparation

Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Attenuated virus helps eliminate cancer in mice

High-flow oxygen technique equally safe as traditional anesthesia in pediatric tubeless airway surgery

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

Microgravity and galactic radiation: Dual threats to astronaut kidney health

Study reveals limitations of cognitive tests in diagnosing concussions among college athletes

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Study uncovers two types of dysbiosis in cystic fibrosis

Crinecerfont: A promising compound for reducing corticosteroid dependence in CAH patients

Head injuries in stunt performers: Unveiling the silent crisis

Study identifies functional sex differences in specialized pain-producing nerve cells

Children exposed to tree and weed pollen at increased risk of respiratory health problems

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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