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Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.

13 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Researchers in Italy review how antioxidants from biological matrices can protect against reproductive issues caused by high-fat diets in women.

11 Jun 2024

Attenuated virus helps eliminate cancer in mice

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice.

11 Jun 2024

Ashwagandha boosts memory and mood in clinical trial

A clinical trial found that acute and 30-day Ashwagandha supplementation improves cognitive function and mood markers, showing significant benefits in memory, attention, and well-being without adverse effects.

10 Jun 2024

Can lifestyles changes reduce Alzheimer’s risk?

Intensive lifestyle changes significantly improve cognition and function in patients with mild cognitive impairment or early dementia due to Alzheimer’s disease over a 20-week period, showing promising results for non-pharmacological interventions.

10 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Teprotumumab shows long-lasting benefits for thyroid eye disease patients

Most patients with thyroid eye disease treated with teprotumumab didn't require additional treatments nearly 2 years later, according to industry-supported research being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass., and published in the journal Thyroid.

10 Jun 2024

New research dispels myths about anesthesia-related cognitive decline

General anesthesia makes it possible for millions of patients each year to undergo lifesaving surgeries while unconscious and free of pain.

10 Jun 2024

Clinical trial demonstrates efficacy of two-drug therapy for methamphetamine addiction

A clinical trial on a two-drug therapy for methamphetamine use disorder reduced use of the highly addictive drug for up to 12 weeks after initiation of treatment, UCLA-led research suggests.

10 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid -; an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 -; proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

New biological mechanism uncovered for treating breast cancer metastasis to the brain

A study led by researchers from the University of Arizona Cancer Center at UArizona Health Sciences identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain.

7 Jun 2024

Study finds service dogs reduce PTSD, anxiety, and depression in veterans

The associations between psychiatric service dog partnership and post-traumatic stress disorder (PTSD) among veterans.

7 Jun 2024

New 5-minute cognitive test boosts dementia care in diverse elderly populations

The 5-Cog tool significantly enhances dementia diagnosis and care for older adults in primary care, especially among Black and Hispanic communities, by being culturally sensitive and quick to administer.

6 Jun 2024

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

In a groundbreaking advance that could revolutionize bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

6 Jun 2024

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

In a world-first, Australian researchers and clinicians have shown that precision medicine – where treatment is tailored to an individual child's cancer – leads to significantly improved outcomes in children with high risk cancer.

6 Jun 2024

Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Patients with atrial fibrillation (Afib) who took low doses of blood-thinning medications known as direct oral anticoagulants (DOACs) experienced more bleeding episodes during the first three months of treatment and about one in five had high blood levels of the medications, compared with similar patients who took standard doses of the same medications, according to a study published in Blood Advances.

6 Jun 2024

Researchers investigate the feasibility of new home-administered treatment for binge eating disorder

Researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London have investigated the feasibility of a new home-administered treatment for binge eating disorder.

6 Jun 2024

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Clinical Trial News and Research

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Changing antibiotic delivery method improves sepsis outcomes globally

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Attenuated virus helps eliminate cancer in mice

Ashwagandha boosts memory and mood in clinical trial

Can lifestyles changes reduce Alzheimer’s risk?

Precision-guided treatment boosts outcomes in children with high-risk cancers

Teprotumumab shows long-lasting benefits for thyroid eye disease patients

New research dispels myths about anesthesia-related cognitive decline

Clinical trial demonstrates efficacy of two-drug therapy for methamphetamine addiction

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

New biological mechanism uncovered for treating breast cancer metastasis to the brain

Study finds service dogs reduce PTSD, anxiety, and depression in veterans

New 5-minute cognitive test boosts dementia care in diverse elderly populations

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

Low-dose direct oral anticoagulants linked to increased bleeding risk in Afib patients

Researchers investigate the feasibility of new home-administered treatment for binge eating disorder

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