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Dose reduction of glucocorticoids in systemic lupus erythematosus

Glucocorticoids are a mainstay of treatment for systemic lupus erythematosus (SLE). But due to long-term adverse effects, dose reduction is becoming a crucial part of treat-to-target management goals.

13 Jun 2024

New insights into blood precursors of pathogenic macrophages in RA

The exact origin and precursor differentiation route of tissue macrophages remains controversial. At the 2024 congress of EULAR - The European Alliance of Associations for Rheumatology - new work sheds light on blood precursors of pathogenic tissue macrophages.

13 Jun 2024

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Funding instability plagues program that brings docs to underserved areas

For Diana Perez, a medical resident at the Family Health Center of Harlem, the handwritten thank-you note she received from a patient is all the evidence she needs that she has chosen the right training path.

13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

Study links antidepressant use and epigenetic aging to higher mortality risk in postmenopausal women

The impact of depressive symptoms, use of antidepressants, and epigenetic age acceleration (EAA) on mortality in postmenopausal individuals.

13 Jun 2024

Replacing TV time with light activity or sleep boosts healthy aging odds

Sedentary behavior reduces the odds of healthy aging, while light physical activity increases them. Replacing TV time with light activity, exercise, or sleep improves healthy aging odds.

13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Prolonged depression in young adults linked to cognitive decline in middle age

People who experience prolonged depressive symptoms starting in young adulthood may have worse thinking and memory skills in middle age, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Many young adults who began vaping as teens can’t shake the habit

G Kumar’s vaping addiction peaked in college at the University of Colorado, when flavored, disposable vapes were taking off.

12 Jun 2024

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Researchers determine the impact of nutrient deficiencies on mortality risk in older adults with hypertension.

12 Jun 2024

Climate change-related environmental stressors associated with increased CVD mortality

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.

12 Jun 2024

Inflammation in mid-life as a predictor of mobility decline in older age

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed-;an indicator of mobility-;20 years later.

12 Jun 2024

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries.

12 Jun 2024

The unregulated sale of Amanita muscaria mushrooms needs a public health response

The legal status, safety, and availability of Amanita muscaria.

12 Jun 2024

Waist-to-height ratio surpasses conventional metrics in predicting cardiovascular disease risk

Research shows waist-to-height ratio (WHtR) outperforms body fat percentage (BF%) and other central obesity measures in predicting ischemic cardiovascular disease (CVD) risk.

12 Jun 2024

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Knee osteoarthritis (OA) is a common cause of pain and joint stiffness. And while physical activity is known to ease symptoms, only one in 10 people regularly exercise.

11 Jun 2024

Microgravity and galactic radiation: Dual threats to astronaut kidney health

The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardize any mission to Mars, according to a new study led by researchers from UCL.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

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Education News and Research

Dose reduction of glucocorticoids in systemic lupus erythematosus

New insights into blood precursors of pathogenic macrophages in RA

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Funding instability plagues program that brings docs to underserved areas

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

Study links antidepressant use and epigenetic aging to higher mortality risk in postmenopausal women

Replacing TV time with light activity or sleep boosts healthy aging odds

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Prolonged depression in young adults linked to cognitive decline in middle age

Many young adults who began vaping as teens can’t shake the habit

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Climate change-related environmental stressors associated with increased CVD mortality

Inflammation in mid-life as a predictor of mobility decline in older age

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

The unregulated sale of Amanita muscaria mushrooms needs a public health response

Waist-to-height ratio surpasses conventional metrics in predicting cardiovascular disease risk

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Microgravity and galactic radiation: Dual threats to astronaut kidney health

Mount Sinai researchers use AI to identify 17 key genes in heart disease

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

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