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Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

Study reveals that human gut bacteria, particularly Mitsuokella jalaludinii, efficiently degrade dietary phytate into short-chain fatty acids, enhancing health benefits through microbial synergy.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Study identifies H5N1 influenza as the cause of an outbreak among dairy cattle in Texas, highlighting the risk of multi-species viral transmission and potential implications for human health.

11 Jun 2024

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

Innovative blood test boosts accuracy of lung cancer screening

A blood-based, cell-free deoxyribonucleic acid (cfDNA) fragmentome assay for lung cancer detection.

11 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Genome sequencing identifies genetic disorders missed by exome analysis

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

10 Jun 2024

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications.

10 Jun 2024

Host RNA incorporation linked to chronic hepatitis E infection

If the virus incorporates host genetic segments into its genome, the infection may become chronic.

10 Jun 2024

Study uncovers gut microbes' role in childhood obesity

Researchers used Mendelian randomization to identify causal links between gut microbes and childhood obesity, revealing key microbial players that influence pediatric adiposity.

10 Jun 2024

Inherited gene sequences predict breast cancer type and severity, study reveals

A Stanford Medicine study of thousands of breast cancers has found that the gene sequences we inherit at conception are powerful predictors of the breast cancer type we might develop decades later and how deadly it might be.

7 Jun 2024

Study sheds light on the rate and nature of mutations in mitochondrial DNA

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its maternal transmission.

7 Jun 2024

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Pre-clinical trials: A new therapeutic approach for the severe condition uses modified viruses to replace a missing protein in the brain.

7 Jun 2024

MGI Tech launches whole workflow solution for agricultural large-scale low-pass whole genome sequencing at PAG Asia 2024

MGI Tech Co., Ltd. (“MGI”), a company committed to building core tools and technologies that drive innovation in life science, today announced a highly efficient whole workflow solution for agricultural large-scale Low-pass whole genome sequencing (Low-pass WGS) based on its proprietary DNBSEQTM platforms during this year’s International Plant and Animal Genome Conference Asia (PAG Asia 2024), taking place on June 5-7 in Shenzhen, China.

From MGI 7 Jun 2024

Does cannabis use cause erectile dysfunction?

Study found no causal link between cannabis use and erectile dysfunction or changes in sex hormone levels using Mendelian randomization analysis.

7 Jun 2024

Genetic discovery reveals key to inflammatory diseases

Researchers discovered that a specific haplotype on chromosome 21 is linked to five inflammatory diseases, offering insights into potential new treatments.

7 Jun 2024

AI-powered liquid biopsy shows promise in early detection of lung cancer

Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers from the Johns Hopkins Kimmel Cancer Center and other institutions have developed and validated a liquid biopsy that may help identify lung cancer earlier.

6 Jun 2024

Genome News and Research

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

UD researchers pioneer universal, economical method for proteomics sample preparation

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Innovative blood test boosts accuracy of lung cancer screening

Precision-guided treatment boosts outcomes in children with high-risk cancers

Genome sequencing identifies genetic disorders missed by exome analysis

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Host RNA incorporation linked to chronic hepatitis E infection

Study uncovers gut microbes' role in childhood obesity

Inherited gene sequences predict breast cancer type and severity, study reveals

Study sheds light on the rate and nature of mutations in mitochondrial DNA

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

MGI Tech launches whole workflow solution for agricultural large-scale low-pass whole genome sequencing at PAG Asia 2024

Does cannabis use cause erectile dysfunction?

Genetic discovery reveals key to inflammatory diseases

AI-powered liquid biopsy shows promise in early detection of lung cancer

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