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Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

10 Jun 2024

Key protein orco crucial for ant olfactory neuron survival and social behavior

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

7 Jun 2024

Novel CMOS sensor captures fast and subtle neural voltage fluctuations

Neurons communicate electrically so to understand how they produce brain functions such as memory, neuroscientists must track how their voltage changes-;sometimes subtly-;on the timescale of milliseconds.

7 Jun 2024

Advanced imaging reveals hidden differences in T cell activation

From the outside, most T cells look the same: small and spherical. Now, a team of researchers led by Berend Snijder from the Institute of Molecular Systems Biology at ETH Zurich has taken a closer look inside these cells using advanced techniques.

6 Jun 2024

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

6 Jun 2024

Fertility warning: SARS-CoV-2 can linger in sperm for months after infection

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality.

4 Jun 2024

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

The production of antibodies, essential for protecting our body against infections, is very well regulated through the action of a specific subtype of immune system cells, follicular helper lymphocytes.

4 Jun 2024

Researchers develop a simpler and more effective screening method for cervical cancer

Researchers at Karolinska Institutet in Sweden and the University of Innsbruck in Austria have developed a simpler and more effective screening method for cervical cancer than the method used today.

4 Jun 2024

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

A group of researchers developed human Cervical Organ Chips to model the cervical interface.

4 Jun 2024

Discovery of antibiotic lolamicin that targets deadly bacteria without harming gut microbiome

Researchers discovered lolamicin, a selective Gram-negative antibiotic, effective against multidrug-resistant pathogens while sparing the gut microbiome.

4 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Super-resolution microscopy offers high-resolution view of virus replication inside cells

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications.

31 May 2024

Researchers decode spatial structure of prime editor

Joint research led by Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo determined the spatial structure of various processes of a novel gene-editing tool called "prime editor."

29 May 2024

New ultrasound method reveals minute vascular structures using contrast agents

A touch of the button is all it takes to improve the resolution of ultrasound images fivefold. This is down to bubbles floating in the bloodstream and a clever algorithm.

29 May 2024

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

The antiviral efficacy and therapeutic potential of harmol in treating herpes simplex virus type 1 (HSV-1) induced keratitis

29 May 2024

New subset of T cells may enhance cancer immunotherapy

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

28 May 2024

Researchers discover how protein XPD detects and repairs DNA damage

Researchers at the University of Würzburg, led by Caroline Kisker in cooperation with Claudia Höbartner, discovered how the protein XPD detects a severe DNA damage and controls its repair.

28 May 2024

Study finds human body lice can transmit plague bacteria

Researchers adapted a strain of human body lice to study their infection dynamics with Yersinia pestis, finding that lice can become infected and transmit the plague bacterium.

26 May 2024

Microscopy News and Research

Understanding Crohn's disease through 'mini-gut' models

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

Key protein orco crucial for ant olfactory neuron survival and social behavior

Novel CMOS sensor captures fast and subtle neural voltage fluctuations

Advanced imaging reveals hidden differences in T cell activation

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

Fertility warning: SARS-CoV-2 can linger in sperm for months after infection

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

Researchers develop a simpler and more effective screening method for cervical cancer

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

Discovery of antibiotic lolamicin that targets deadly bacteria without harming gut microbiome

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Super-resolution microscopy offers high-resolution view of virus replication inside cells

Researchers decode spatial structure of prime editor

New ultrasound method reveals minute vascular structures using contrast agents

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

New subset of T cells may enhance cancer immunotherapy

Researchers discover how protein XPD detects and repairs DNA damage

Study finds human body lice can transmit plague bacteria

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