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Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

The impact of broccoli sprouts and its role in resolving Crohn’s disease symptoms.

14 Nov 2023

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

Broccoli sprouts diet protects mice from Crohn's disease, study shows

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice.

9 Nov 2023

Yabing Chen receives NIH grants to advance vascular disease research

Yabing Chen, Ph.D., has been awarded two National Institutes of Health grants totaling more than $5 million to further her research into vascular diseases ranging from hardening of the arteries to dementia.

6 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Discovery of protein interaction could lead to new schizophrenia treatments

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

26 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

How does nutrition influence osteoarthritis prevention and management?

The influence of nutrition on osteoarthritis (OA).

16 Oct 2023

Genetically edited chickens show resistance to avian influenza in landmark study

Researchers use CRISPR technology to create chickens resistant to avian influenza, targeting specific genes to inhibit viral replication. The study reveals both the promise and complexities of using genetic editing as a disease control strategy, also shedding light on influenza's adaptability.

11 Oct 2023

Recent Advancements in Cell Based Therapy

In this interview, NewsMedical talks to James Brady about cell-based therapy and how the field of genetic engineering transformed.

From MaxCyte, Inc. 11 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

Knockout News and Research

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

Changing environment can have long-term, significant effects on the brain

Broccoli sprouts diet protects mice from Crohn's disease, study shows

Yabing Chen receives NIH grants to advance vascular disease research

TIMP2 protein identified as key player in brain plasticity and memory

How one gene shakes up our understanding of male infertility

Discovery of protein interaction could lead to new schizophrenia treatments

Brain natriuretic peptide plays a role in activating atopic dermatitis

How does nutrition influence osteoarthritis prevention and management?

Genetically edited chickens show resistance to avian influenza in landmark study

Recent Advancements in Cell Based Therapy

Discovery of a novel therapeutic target for pancreatic cancer

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Study demonstrates novel role of Axin1 in mediating intestinal homeostasis and microbiota

Researchers identify a rare cause of male infertility and discover a potential cure

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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