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Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

The world's population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022.

23 May 2024

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO).

21 May 2024

Ketogenic diets linked to cellular aging in vital organs, new study finds

Study reveals that ketogenic diets induce cellular senescence in mice, affecting organs like the kidneys and heart through AMPK and p53 pathways. These findings highlight potential long-term risks associated with ketogenic diets.

20 May 2024

Study identifies PI3K-beta as key target in overcoming chemotherapy resistance in glioblastoma

For many patients with a deadly type of brain cancer called glioblastoma, chemotherapy resistance is a big problem.

20 May 2024

Mechanistic insights into the role of huc-mscs in treating acute liver failure

Acute liver failure (ALF) is a life-threatening clinical problem with limited treatment options. Administration of human umbilical cord mesenchymal stem cells (hUC-MSCs) may be a promising approach for ALF.

16 May 2024

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

The adipose-neural axis plays an important role in arrhythmogenesis.

15 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

A study in Cell Reports Medicine used an in vitro co-culture of adipocytes, cardiomyocytes, and sympathetic neurons to reveal that the adipose-neural axis plays a crucial role in arrhythmogenesis, driven by interactions between epicardial adipose tissue and the sympathetic nervous system.

14 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.

9 May 2024

Placental DNA methylation patterns altered by pregnancy air pollution exposure, research reveals

The relationship between prenatal air pollutant exposure concentrations and changes in placental deoxyribonucleic acid (DNA) methylation.

9 May 2024

Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier.

6 May 2024

Research highlights the link between mitochondrial calcium transport and autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction. Autophagy occurs when cells break down and reuse their own cytoplasm.

2 May 2024

Kinase News and Research

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

Ketogenic diets linked to cellular aging in vital organs, new study finds

Study identifies PI3K-beta as key target in overcoming chemotherapy resistance in glioblastoma

Mechanistic insights into the role of huc-mscs in treating acute liver failure

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

Genetic link identified between inflammatory bowel disease and Parkinson's disease

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

New insights into Chaga mushroom's mechanisms for fighting oral cancer

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Placental DNA methylation patterns altered by pregnancy air pollution exposure, research reveals

Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Research highlights the link between mitochondrial calcium transport and autophagy

Father's gut health in mice linked to offspring's well-being, study finds

Aspirin shows no benefit in preventing breast cancer recurrence, study finds

Study links agricultural pesticide exposure to increased genetic variants in Parkinson’s disease

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

Exploring the potential of ketogenic diets in managing epilepsy

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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