Positron Emission Tomography News and Research

RSS

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

$Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy$

Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy

A research team at Osaka University will start an investigator-initiated clinical trial for refractory prostate cancer patients after the successful development of a new alpha-ray therapeutic agent ([At-211] PSMA-5) and confirmation of its efficacy in animal models.

27 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

New discovery offers dietary solution for pulmonary hypertension

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.

2 May 2024

PET brain scans could reveal hidden inflammation in patients with multiple sclerosis

A Brigham and Women’s Hospital study of 30 people found that, in patients with MS, advanced brain imaging could identify hidden inflammation not picked up on traditional MRIs

27 Apr 2024

UC San Diego researchers secure NIH grants to develop noninvasive immune cell imaging technology

Researchers at University of California San Diego School of Medicine have been awarded two new grants by the National Institutes of Health (NIH), totaling $6.7 million, to develop and clinically test technologies that can noninvasively examine and quantify immune cells found in tumors.

1 Apr 2024

Study demonstrates safe reduction of lymph node removal in breast cancer patients

Patients with breast cancer that has started to spread to the lymph nodes in the armpit can safely avoid extensive removal of the lymph nodes if their treatment is tailored to their response to cancer-killing therapies such as chemotherapy before surgery.

22 Mar 2024

Combined scanning technique could refine treatment for early-stage breast cancer patients

Using a combined scanning technique on patients with early-stage breast cancer improved treatment in almost three out of ten cases in a trial presented at the 14th European Breast Cancer Conference today.

21 Mar 2024

Computer model can find signs of lymph node cancer in 90% of cases

Medical image analysis using AI has developed rapidly in recent years. Now, one of the largest studies to date has been carried out using AI-assisted image analysis of lymphoma, cancer of the lymphatic system.

14 Mar 2024

Study highlights potential of p-tau217 assays in Alzheimer's clinical trials and diagnosis

The performance of two commercial phospho-tau217 (p-tau217) assays.

14 Mar 2024

Study reveals link between blood amyloid levels and brain microstructure changes in Alzheimer's

New research published today suggests there is a link between abnormal blood levels of amyloid -; a protein associated with Alzheimer's disease -; and subtle changes in brain microstructures on a type of MRI, findings that could lead to a new way to detect Alzheimer's earlier in people with no clinical signs.

6 Mar 2024

How does cancer impact cognitive decay?

The risk of mild cognitive impairment (MCI) and Alzheimer's disease (AD) among cancer patients.

26 Feb 2024

Blood test rivals spinal fluid analysis in Alzheimer's detection

A study reveals blood test %p-tau217 matches or surpasses CSF tests in detecting Alzheimer's disease pathology, offering a less invasive, equally accurate alternative for diagnosis across various stages.

22 Feb 2024

Simple blood test to detect Alzheimer's disease may replace more invasive diagnostic methods

A simple blood test to diagnose Alzheimer's disease soon may replace more invasive and expensive screening methods such as spinal taps and brain scans.

22 Feb 2024

Wastewater clues could revolutionize Alzheimer's detection

Review explores the potential of wastewater-based epidemiology (WBE) for diagnosing Alzheimer's disease (AD) through biomarkers in biofluids, offering a non-invasive, cost-effective approach to early detection and large-scale monitoring.

18 Feb 2024

Fluorescent sensor array accurately detects multiple amyloids in biological samples

Many neurodegenerative diseases, including Alzheimer's and Parkinson's, are difficult to diagnose before symptoms begin to appear.

5 Feb 2024

Large study confirms locked-in syndrome as the predominant outcome of non-fatal pediatric drowning

It is a far cry from the traditionally thought-of "vegetative state" in which the mind is absent while the body lives on. Indeed, it is the opposite.

25 Jan 2024

What are the capabilities of a commercially available p-tau217 immunoassay to identify Alzheimer disease pathophysiology?

Researchers determined the utility of a novel and commercially available immunoassay for plasma phosphorylated tau 217 to detect Alzheimer's Disease pathology and evaluate reference ranges for abnormal amyloid β and longitudinal change across three selected cohorts.

24 Jan 2024

Revolutionary brain scan lights up glioma's Achilles heel

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) made a new discovery that can revolutionize both the diagnosis and treatment of glioblastoma.

16 Jan 2024

Urea-powered nanorobots reduce bladder tumors by 90% in mice

The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface.