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Study identifies key gluten peptide triggering leaky gut in celiac patients

Today is International Celiac Day. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population.

17 May 2024

Reviving a rejected drug: New selective antibiotic shows promise

Twenty years ago, a drug candidate was rejected due to its side effects. Researchers have now figured out how to potentially make a successor molecule more selective.

17 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

Researchers develop pathoblockers to combat bacterial pneumonia toxins

In most cases, antibiotics are a reliable form of protection against bacterial infections. They have saved billions of human lives since their introduction.

16 May 2024

£85 million funding to support the international community in tackling antimicrobial resistance

Funding of £85 million will be announced at a global event to support the international community in tackling the growing threat of antimicrobial resistance.

16 May 2024

Gut microbiota and obesity: New study shows promising results with probiotic and prebiotic intervention

The effect of a low-calorie, sufficient fiber regimen combined with probiotic supplements and physical activity on health, body composition, and physique.

16 May 2024

COVID-19 virus can breach blood-retinal barrier, study finds

The blood-retinal barrier is designed to protect our vision from infections by preventing microbial pathogens from reaching the retina where they could trigger an inflammatory response with potential vision loss.

14 May 2024

New mechanism discovered to weaken pseudomonas aeruginosa virulence

The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics.

14 May 2024

Study reveals unintended consequences of antibiotic choice in sepsis treatment

In emergency rooms and intensive care units across the country, clinicians make split-second decisions about which antibiotics to give a patient when a life-threatening infection is suspected.

14 May 2024

Scientists unlock mystery behind a deadly strain of cholera bacteria

A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions -; and, with its persistence, baffling scientists.

14 May 2024

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

The effect of gut bacteria on non-high-density lipoprotein cholesterol (non-HDL-c) variations.

14 May 2024

Diet and gut microbiota: how what you eat shapes your gut health

A systematic review published in Gut Microbes found that diet patterns, nutrients, bioactive compounds, and food additives influence gut microbiota. However, the associations were dominated by routinely analyzed nutrients rather than microbiota-relevant nutrients

13 May 2024

Western diet linked to chronic diseases by gut microbiota disruption

The Western diet disrupts gut microbiota and gut barrier function, increasing the risk of non-communicable chronic diseases through chronic low-grade inflammation.

13 May 2024

Researchers discover how gut microbes influence social behavior in mice

For people with autism, constipation, diarrhea, and abdominal pain often go along with the social struggles and repetitive behaviors that define the condition.

13 May 2024

ERS Genomics appoints John E Milad as Chief Executive Officer

ERS Genomics Limited (‘ERS’), the CRISPR licensing company, today announced the appointment of John E Milad as CEO, with immediate effect. John brings over 25 years of experience as an executive leader, venture capitalist, and investment banker focused on the life sciences and medical technology sectors.

From ERS Genomics 13 May 2024

Scripps Research professor emeritus John Johnson selected as member of the National Academy of Sciences

Scripps Research professor emeritus John Johnson, PhD, has been elected to the National Academy of Sciences—one of the highest honors given to scientists.

11 May 2024

Researchers discover a 'training program' driving parietal cell development

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the body that produce acid.

10 May 2024

New collaboration to combat river blindness and lymphatic filariasis

Prof. Achim Hoerauf, Director of the Institute of Medical Microbiology, Immunology and Parasitology at the University Hospital Bonn (UKB), and his team have succeeded in collaborating with the Department of Pharmaceutical Technology and Biopharmacy at the University of Bonn and the Helmholtz Center for Infection Research (HZI), to enter into a partnership with the Japanese pharmaceutical company Eisai for the further development of the antibiotic corallopyronin A (CorA) as a treatment for the neglected tropical diseases river blindness and lymphatic filariasis and to raise a large amount of funding.

10 May 2024

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Modified ketogenic diet modulates gut microbiome, inflammatory markers, and brain-related miRNAs in autistic children, correlating with improved behavioral symptoms. The diet increases beneficial gut bacteria and reduces inflammatory cytokines and BDNF levels.

9 May 2024