ACE Inhibitors News and Research

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ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Combination treatments reduce blood pressure in patients taking ibrutinib

Combination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutinib, according to a new study published in Blood Advances.

5 Feb 2024

Two new practice parameters offer recommendations for treating anaphylaxis and atopic dermatitis

Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients.

18 Dec 2023

ARAMIS trial finds no benefit of anakinra in acute myocarditis

The largest randomized controlled trial of patients with acute myocarditis has found that anakinra is safe but does not reduce complications. The late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Patients affected by depression more likely to stop taking their heart medications

Patients who feel low when having a cardiac device implanted are more likely to stop taking their heart medications than those without depression, according to research presented today at ACNAP 2023, a scientific congress of the European Society of Cardiology.

25 Jun 2023

The link between Covid-19 and Alzheimer's disease established

Renin-angiotensin system, or RAS, is a physiological mechanism essential to human body function. The SARS-CoV-2 virus causes overactivation and malfunction of this system.

21 Jun 2023

Young women who experience a heart attack more likely to be rehospitalized after discharge

Young women who experience a heart attack have more adverse outcomes and are more likely to end up back in the hospital compared to men of a similar age in the year following discharge.

2 May 2023

Virtual care team strategy found to be safe and effective in improving treatment for heart failure patients

Recent studies have provided strong evidence that patients with heart failure can benefit from medical therapies that can reduce risk of worsening symptoms and extend patients' lives.

7 Mar 2023

MINOCA: Insights into a type of heart attack that predominantly affects women

Heart disease is the leading cause of death among women in the U.S., and a type of heart attack called myocardial infarction with non-obstructive coronary arteries (MINOCA), which predominantly affects women, is garnering increased attention.

30 Jan 2023

UT Southwestern physician-scientist wins NIH award to support heart regeneration research

UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.

30 Jan 2023

Dapagliflozin improves morbidity reduces risk of death in heart failure patients

Researchers investigate the safety and efficacy of dapagliflozin among heart failure patients with improved ejection fraction.

19 Dec 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

Diabetes patients on Medicare Advantage plans less likely to be prescribed newer, more expensive medicines

While patients with diabetes on Medicare Advantage plans are more likely to receive preventive treatments, they were less likely to be prescribed newer, more expensive medications and were more likely to have higher blood pressure and worse blood glucose control than patients on Medicare Fee-For-Service plans, according to a new study led by a University of Pittsburgh School of Medicine physician-scientist.

7 Jul 2022

Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

Assessment of England's medication prescribing safety during COVID pandemic

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on the prescribing safety of high-risk medications on a national scale in England.

11 May 2022

Personalized text messaging program improves healthy lifestyle measures in heart attack survivors

A text messaging program successfully supported, informed and motivated people after a heart attack on how to prevent a second heart attack, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

9 May 2022

ACE Inhibitors News and Research

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