ACE Inhibitors News and Research

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ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

Important new lessons learned from aspirin

No other medicine is as common, inexpensive, and yet powerful in so many ways as aspirin; yet despite a century of experience with the drug, researchers are still learning important new lessons, while raising new questions, according to seven special articles in the Sept. 20, 2005, issue of the Journal of the American College of Cardiology.

20 Sep 2005

Strokes and heart attacks can be prevented in people with high blood pressure

Most strokes and heart attacks in people with high blood pressure can be abolished by simply combining effective, modern blood pressure lowering drugs with treatment to reduce cholesterol.

6 Sep 2005

Benefits of starting CHF treatment with beta-blocker, bisoprolol

Initiating treatment with the selective beta-blocker, bisoprolol, is as effective and well tolerated as beginning treatment with an ACE inhibitor. However, starting treatment with bisoprolol may reduce the risk of death especially in the first year of treatment.

5 Sep 2005

Nurse-led multidisciplinary programme can help coronary patients and their families to reduce their risk of major cardiovascular disease

Early results from the EuroAction hospital project, announced today at the European Society of Cardiology, demonstrate how a nurse-led multidisciplinary programme, organised in busy general hospitals, can help coronary patients and their families to reduce their risk of major cardiovascular disease (CVD).

5 Sep 2005

Chronic heart failure (CHF) is common, deadly, disabling, costly but fortunately - treatable

During the last ten to 15 years, treatment of CHF has been dramatically improved by pharmacological therapy and devices. Treatment also has become more complicated.

5 Sep 2005

International SHAPE project reveals massive public lack of awareness on heart failure

An international survey of the public's awareness of heart failure has revealed a woeful and worrying level of ignorance, according to the lead author of the research, which is published (Wednesday 31 August) in Europe's leading cardiology journal European Heart Journal.

31 Aug 2005

FDA approval for Diovan (Valsartan)

Novartis Pharmaceuticals Corporation announced today that the US Food and Drug Administration (FDA) approved Diovan (valsartan), the most prescribed ARB (angiotensin receptor blocker) in the US and worldwide, for a new indication to reduce cardiovascular death in patients at high risk (with left ventricular failure or left ventricular dysfunction) following a heart attack.

4 Aug 2005

Not enough women take part in heart drug trials

Scientists say because women are under-represented in the clinical trials of heart drugs, doctors are left in the dark as to how treatments may work differently in their bodies.

3 Aug 2005

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

The study found that almost three fourths of those 80 years and older have hypertension -- blood pressure greater than 140 systolic over greater than 90 diastolic. Fewer than 10 percent have "normal" blood pressure levels -- less than 120 systolic over less than 80 diastolic.

26 Jul 2005

GenoMed submits 50th provisional patent application

GenoMed announced today that the Company has submitted its 50th provisional patent application, a major milestone in any development stage company. GenoMed has so far been awarded two patents, one for treating acute kidney failure without dialysis, and another for hastening lung maturation in prematurely born infants.

26 Jul 2005

Eplerenone shows benefit for patients with damaged hearts

In the first thirty days following a heart attack, one in three deaths among patients with signs of heart failure may be preventable by early treatment with a drug called eplerenone (Inspra, Pfizer Ltd), according to new data published in the Journal of the American College of Cardiology (JACC).

26 Jul 2005

ACE inhibitors should be available at no cost to the 8 million Americans over age 65 who have diabetes

Nothing in life is free, the old saying goes. But maybe some things should be, according to a new University of Michigan Health System study.

18 Jul 2005

Study compares four standard measures for heart failure treatment

UCLA investigators found large gaps and marked variation in U.S. hospitals' heart failure treatment based on adherence to four standard quality measures. The study points to the need for hospitals to establish education programs and systems to improve quality of care for this patient population.

11 Jul 2005

Major study says for diabetics with high blood pressure diuretics are the best option

A major new study has found that for people with type 2 diabetes and high blood pressure, cheaper diuretic medications may be the most cost-effective option in reducing hypertension.

29 Jun 2005

Diuretics work better than newer and more costly medicines for diabetics with high blood pressure

Diuretics (water pills) work better than newer and more costly medicines in the treatment of high blood pressure and prevention of some forms of heart disease in people with type 2 diabetes, according to results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

28 Jun 2005

ACE Inhibitors News and Research

Further Reading

Important new lessons learned from aspirin

Strokes and heart attacks can be prevented in people with high blood pressure

Benefits of starting CHF treatment with beta-blocker, bisoprolol

Nurse-led multidisciplinary programme can help coronary patients and their families to reduce their risk of major cardiovascular disease

Chronic heart failure (CHF) is common, deadly, disabling, costly but fortunately - treatable

International SHAPE project reveals massive public lack of awareness on heart failure

FDA approval for Diovan (Valsartan)

Not enough women take part in heart drug trials

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

GenoMed submits 50th provisional patent application

Eplerenone shows benefit for patients with damaged hearts

ACE inhibitors should be available at no cost to the 8 million Americans over age 65 who have diabetes

Study compares four standard measures for heart failure treatment

Major study says for diabetics with high blood pressure diuretics are the best option

Diuretics work better than newer and more costly medicines for diabetics with high blood pressure

National Service Framework for chronic heart failure is urgently needed

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Diabetes knowledge has little effect on improving outcomes

Latest patterns of medication use in the U.S.

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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