Acid Reflux News and Research

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Acid reflux disease is a condition that often results when a valve located at the end of the esophagus malfunctions. When this valve relaxes inappropriately, it may allow stomach acid to splash up and irritate the lining of the esophagus, creating the sensation called heartburn, and other uncomfortable symptoms. Frequent, persistent heartburn is the primary symptom associated with acid reflux disease or GERD.

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

UCSF study identifies cells responsible for cough reflex

When a mouthful of water goes down the wrong pipe – heading toward a healthy person’s lungs instead of their gut – they start coughing uncontrollably.

18 Apr 2024

Survey highlights the lack of awareness about deadly chronic acid reflux

A new survey has revealed the overwhelming lack of knowledge about the causes and symptoms of hiatus hernia and chronic acid reflux in the UK. These results come despite the fact that 1 in 3 people aged over 50 have hiatus hernia and 13 million people suffer from chronic acid reflux.

4 Sep 2023

Dementia risk may increase with long-term use of acid reflux drugs

People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

9 Aug 2023

Obesity management: a women's health approach

Researchers provide a women's health perspective on obesity.

1 May 2023

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Poor quality sleep may bolster a person's genetic susceptibility to asthma, potentially doubling their risk of being diagnosed with the condition, suggests a large UK Biobank study, published in the open access journal BMJ Open Respiratory Research.

4 Apr 2023

Study shows how RNA biomarkers may be used to confirm heart disease

When patients begin to experience chest pain or shortness of breath while exercising, doctors may struggle to correctly diagnose if the problem is caused by coronary artery disease.

28 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Loyalty card data on over-the-counter drug purchases could help spot ovarian cancer cases earlier

Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier according to a pioneering study funded by Cancer Research UK.

26 Jan 2023

Transgender people in rural America struggle to find doctors willing or able to provide care

For Tammy Rainey, finding a health care provider who knows about gender-affirming care has been a challenge in the rural northern Mississippi town where she lives.

23 Jan 2023

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

New report shines light on the impact of COVID-19 on general practice in Australia

A new report reveals some of the effects of the COVID-19 pandemic on general practice in Australia. The data used is poised to shine a light on how COVID-19 affects long-term health.

14 Sep 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Rampant inflammation has long been linked to cancer but exactly how it pushes healthy cells to transform into malignant ones has remained a mystery.

7 Jun 2022

New, minimally invasive biomarker-based strategy 90% successful in detecting esophageal cancer

In a small but rigorous pilot study, Johns Hopkins Medicine researchers have shown that a novel, minimally invasive biomarker-based strategy they developed was 90% successful in detecting esophageal squamous cell carcinoma (ESCC), the predominant subtype of esophageal cancer worldwide.

18 May 2022

Analysis reveals increasing prevalence of esophageal cancer and Barrett’s esophagus in middle-aged adults

Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett's esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week 2022.

13 May 2022

Study shows how DNA changes in Barrett's esophagus cells may predict esophageal cancer

More and more mutations clutter up our DNA as we age. Mostly, these don't cause problems. But sometimes, a switch will flip, and a mutated cell turns cancerous. Can we see this shift in time to prevent or treat cancer before it starts?

28 Apr 2022

Study points to vagus nerve dysfunction as a central pathophysiological feature of long COVID

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) suggests that many of the symptoms connected to post-COVID syndrome (PCC, also known as long COVID) could be linked to the effect of the virus on the vagus nerve – one of the most important multi-functional nerves in the body.

12 Feb 2022

Novel diagnostic platform offers hope for early detection of cancer in patients with Barrett’s esophagus

On a mission to increase early detection of esophageal cancer, University of Colorado (CU) Cancer Center member Sachin Wani, MD, is leading a study to see if a novel diagnostic platform can help endoscopists better identify the disease in patients with a condition called Barrett's esophagus.

8 Feb 2022