Acid Reflux News and Research

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Acid reflux disease is a condition that often results when a valve located at the end of the esophagus malfunctions. When this valve relaxes inappropriately, it may allow stomach acid to splash up and irritate the lining of the esophagus, creating the sensation called heartburn, and other uncomfortable symptoms. Frequent, persistent heartburn is the primary symptom associated with acid reflux disease or GERD.

Antacid medicines improve overall survival in patients with head and neck cancer

Patients with head and neck cancer who used antacid medicines to control acid reflux had better overall survival, according to a new study from the University of Michigan Comprehensive Cancer Center.

2 Dec 2014

New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

Before reaching for that daily antacid, you might consider what it's doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among their gut bacteria, putting them at increased risk for infections like clostridium difficile and pneumonia, in addition to vitamin deficiencies and bone fractures.

25 Nov 2014

Study shows that obese children may mistake asthma symptoms, overuse rescue medications

New research shows obese children with asthma may mistake symptoms of breathlessness for loss of asthma control leading to high and unnecessary use of rescue medications. The study was published online in the Journal of Allergy and Clinical Immunology, the official scientific journal of the American Association of Allergy, Asthma and Immunology.

27 Oct 2014

Insulin can protect cells of pancreas from acute pancreatitis

Scientists from The University of Manchester have discovered that insulin can protect the cells of the pancreas from acute pancreatitis - a disease for which there is currently no treatment.

21 Aug 2014

First diagnostic criteria proposed for Christianson Syndrome

Because the severe autism-like condition Christianson Syndrome was only first reported in 1999 and some symptoms take more than a decade to appear, families and doctors urgently need fundamental information about it. A new study that doubles the number of cases now documented in the scientific literature provides the most definitive characterization of CS to date.

22 Jul 2014

Study: Dietary elimination is successful method of treatment for adults with EoE

Dietary elimination is a successful method of treatment for adults with eosinophilic esophagitis (EoE), according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

21 Jul 2014

Ironwood Pharmaceuticals starts Phase IIa clinical study of IW-3718 for gastroesophageal reflux disease

Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) announced today that dosing has begun in its Phase IIa clinical study of its investigational compound IW-3718 in patients suffering from gastroesophageal reflux disease (GERD) who have not responded adequately to treatment with a proton pump inhibitor (PPI). Data are expected in the first half of 2015.

18 Mar 2014

TV series House helps doctors diagnose Cobalt intoxication of patient with hip replacement

In today’s edition of The Lancet [Friday 7 February], doctors report the case of a patient with severe heart failure, who in May 2012 was referred to the Marburg University clinic in Germany.

10 Feb 2014

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Generally speaking, reflux has been a major chronic issue for probably the last 40 or 50 years. When you look at the global population, depending on which country we're talking about, around 20% to 40% of individuals have reflux disease within their populations.

23 Dec 2013

Brazilian study provides evidence to support effectiveness of Tecta in erosive GERD

Takeda Pharmaceuticals International GmbH announced today results showing pantoprazole magnesium 40 mg (Tecta) was as effective as esomeprazole 40 mg for achieving complete remission (defined as combined endoscopic healing and symptomatic relief) and the mucosal healing rate was high, whilst providing significantly higher symptom relief after 8 weeks.

13 Dec 2013

Insomnia linked to increased GERD risk

Insomnia is associated with an increased risk for gastroesophageal reflux disease, findings from a cross-sectional study show.

9 Dec 2013

Better understanding of cancer evolution could help in early detection of cancers

A new appreciation of how cancer cells evolve could help scientists design better screening methods to catch cancer before it advances.

4 Dec 2013

Experts explain how to prevent heartburn during holidays

Attracted by the decadent treats, fried meats, and festive cocktails of the Thanksgiving-to-New-Year feast, heartburn can be an unwelcome guest during the holidays. According to the American Society for Gastrointestinal Endoscopy, acid reflux affects about 30 million Americans.

3 Dec 2013

First generic versions of Aciphex delayed-release tablets get FDA approval for GERD treatment

The U.S. Food and Drug Administration today approved the first generic versions of Aciphex (rabeprazole sodium) delayed-release tablets, used to treat gastroesophageal reflux disease in adults and adolescents (ages 12 and up).

10 Nov 2013

Mayo Clinic: Physical activity is associated with reduced risk of esophageal cancer

Physical activity is associated with a reduced risk of esophageal cancer, according to a new study presented by Mayo Clinic researchers at the American College of Gastroenterology's Annual Scientific Meeting, Oct. 11-16, in San Diego.

15 Oct 2013

EGS announced that enrollment for RESPECT study has surpassed company's original target

EndoGastric Solutions (EGS), the leader in endoluminal reconstructive treatment for gastroesophageal reflux disease (GERD), announced today that enrollment for the RESPECT study (Randomized EsophyX vs. Sham/Placebo Controlled Trial) is complete and has surpassed the company's original target of 120 patients.

9 Oct 2013

Acid Reflux News and Research

Further Reading

Antacid medicines improve overall survival in patients with head and neck cancer

New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

Study shows that obese children may mistake asthma symptoms, overuse rescue medications

Insulin can protect cells of pancreas from acute pancreatitis

First diagnostic criteria proposed for Christianson Syndrome

Study: Dietary elimination is successful method of treatment for adults with EoE

Ironwood Pharmaceuticals starts Phase IIa clinical study of IW-3718 for gastroesophageal reflux disease

TV series House helps doctors diagnose Cobalt intoxication of patient with hip replacement

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Brazilian study provides evidence to support effectiveness of Tecta in erosive GERD

Insomnia linked to increased GERD risk

Better understanding of cancer evolution could help in early detection of cancers

Experts explain how to prevent heartburn during holidays

First generic versions of Aciphex delayed-release tablets get FDA approval for GERD treatment

Mayo Clinic: Physical activity is associated with reduced risk of esophageal cancer

EGS announced that enrollment for RESPECT study has surpassed company's original target

Blocking pathway might prevent esophageal cancer in patients with existing Barrett's esophagus

Nerve pathways in spinal cord transmit pain signals associated with gastric reflux to the brain

NW ENT adopts Restech Dx-pH Measurement System to detect acid reflux in upper airway

JACS reports study on LINX Reflux Management System for GERD treatment

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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