Acute Kidney Injury News and Research

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Acute kidney injury (AKI) involves sudden damage to the kidneys or decrease in renal function that occurs over a few hours or days. The severity of the condition can vary from a minor loss of kidney function to kidney failure.

Two 'big gun' antibiotics may be safer for the kidneys than previously thought

Two 'big gun' antibiotics thought to cause kidney failure in ICU patients with a severe bacterial infection, especially when combined with another antibiotic, may be safer for the kidneys than previously reported, following a randomized trial led by Vanderbilt University Medical Center.

16 Oct 2023

Acute kidney injury patients on dialysis may be overtreated

Patients with acute kidney injury requiring outpatient dialysis after hospital discharge receive the same care as those with the more common end-stage kidney disease, according to a study led by UC San Francisco.

28 Sep 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

Workers pay the price while Congress and employers debate need for heat regulations

Sometimes the heat makes you vomit, said Carmen Garcia, a farmworker in the San Joaquin Valley of California. She and her husband spent July in the garlic fields, kneeling on the scorched earth as temperatures hovered above 105 degrees.

5 Sep 2023

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Sodium glucose co-transporter-2 (SGLT2) inhibitors do not lead to lower 28-day all-cause mortality compared with usual care or placebo in patients hospitalized with COVID-19, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Inorganic nitrate reduces contrast-induced nephropathy (CIN), improves renal outcomes and reduces cardiac events compared to placebo in patients at risk of renal injury undergoing coronary angiography for acute coronary syndrome, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Physiology-guided complete revascularization reduces ischemic events in older MI patients

Physiology-guided complete revascularization reduces ischemic events compared with culprit-only revascularization in myocardial (MI) infarction patients aged 75 years or older with multivessel disease, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Researchers performed a genome-wide association study to explore whether biomarker levels are causally related to COVID-19 hospitalization.

2 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

The essential role of the MPL36 protein in leptospirosis

The Leptospira membrane protein L36 (MPL36) is essential for its pathogenesis.

31 Jul 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

New precision medicine trial shows promise for treating rare brain tumors

Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients.

13 Jul 2023

Acute kidney injury does not predict worsening kidney function trajectory in CKD patients

A study of hospitalized persons with chronic kidney disease (CKD) fournd that acute kidney injury (AKI) did not predict worsening of kidney function trajectory once difference in pre-hospitalization characteristically were fully accounted for.

10 Jul 2023

Regular cannabis users more likely to experience postoperative complications, study finds

People who are regular cannabis users are at an increased risk of experiencing complications before, during, and after surgery, according to a study by researchers with UTHealth Houston published today in JAMA Surgery.

5 Jul 2023

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) — a sudden loss of kidney function.

5 Jul 2023

Researchers find new way to reduce risk of kidney injury in cardiac surgery patients

When a person has heart surgery, they're often managed on cardiopulmonary bypass.

29 Jun 2023

New tests based on biomarkers may improve diagnosis and treatment of acute kidney injury

Hospital inpatients who develop an acute kidney injury (AKI) generally fare poorly after being discharged, and have few options for effective treatment.

24 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

Post-COVID quality of life: Study reveals long-term challenges for ICU patients

Study aimed to determine the health-related quality of life (HRQoL) of COVID-19 patients after hospitalization. The study found that HRQoL is limited in COVID-19 ICU patients 3- and 12-months post COVID-19 hospitalization, with significantly less improvement at 12-months compared to non-ICU patients. Mental disorders were common, highlighting the complexity of post-COVID-19 symptoms.

27 Apr 2023

Readmission and mortality more likely to happen after hospitalization with acute kidney injury

A study supported by the National Institutes of Health found that people who experienced acute kidney injury (AKI) during a hospitalization, including those admitted with AKI or who developed AKI in the hospital, were more likely to revisit the hospital or die shortly after discharge, compared to people hospitalized without AKI.