Acute Kidney Injury News and Research

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Acute kidney injury (AKI) involves sudden damage to the kidneys or decrease in renal function that occurs over a few hours or days. The severity of the condition can vary from a minor loss of kidney function to kidney failure.

COVID-19 patients with abrupt kidney function decline more likely to die during hospitalization

New research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC), held online this year, suggests that among COVID-19 patients admitted to the intensive care unit (ICU), those who have an abrupt decline in kidney function are more likely to die during hospitalization than those with pre-existing kidney diseases

20 Dec 2021

A promising new therapeutic target for kidney disease

Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective drug treatment for the condition is available.

7 Dec 2021

SARS-CoV-2 can directly invade human kidney cells, research shows

Up to 25% of patients' COVID-19 cases involve acute kidney injury—the kidneys' equivalent of a heart attack.

29 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021

Simple risk score can help predict contrast-associated kidney injury after PCI

A new, updated risk score can help predict possible contrast-associated acute kidney injury (CA-AKI) among patients undergoing percutaneous coronary intervention (PCI), Mount Sinai researchers report.

15 Nov 2021

Potential biomarkers of coagulopathy and disease severity in COVID-19

Scientists have investigated the presence of specific biomarkers in hospitalized COVID-19 patients

15 Nov 2021

Identification of a candidate effector gene at COVID-19 risk locus

A new study focuses on developing a comprehensive platform to decode the effects of sequence variation identified by GWAS.

8 Nov 2021

Inflammatory cytokines may help predict patient outcomes after traumatic injury

Inflammatory cytokines are molecules that are secreted by immune cells to promote inflammation. A study published in the Journal of Orthopaedic Research found that measuring inflammatory cytokines may help predict patient outcomes after traumatic injury, which is the leading cause of mortality in individuals under 50 years of age.

3 Nov 2021

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Scientists explore the link between SARS-CoV-2 infection and anti-NMDAR encephalitis.

1 Nov 2021

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease.

28 Sep 2021

Melatonin reduces kidney failure in people treated with the antibiotic vancomycin

A study by researchers at the Rutgers Ernest Mario School of Pharmacy finds that melatonin significantly reduces kidney failure in people being treated with the antibiotic vancomycin.

15 Sep 2021

COVID-19 associated with increased risk of kidney damage, end-stage kidney diseases

A study by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System shows that people who have had COVID-19, including those with mild cases, are at an increased risk of developing kidney damage as well as chronic and end-stage kidney diseases.

1 Sep 2021

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

During her medical school career, third-year student Skylar Nahi has taken advantage of the mentorship and research opportunities available to Feinberg students.

31 Aug 2021

Higher mortality rates and age-related disease patterns in pediatric COVID-19

The current study examines children in pediatric ICU (PICU) care with COVID-19. Read more here.

25 Aug 2021

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

A new study reports a case of pre-eclampsia complicated by the acute fatty liver of pregnancy (AFLP).

24 Aug 2021

Study examines clinical outcomes in vaccinated individuals hospitalized with SARS-CoV-2 Delta variant

A new study has been published on the medRxiv* preprint server that has evaluated the clinical outcomes of the COVID-19 patients hospitalized in AIG hospitals, Hyderabad, India, between April 24, 2021, and May 31, 2021.

20 Jul 2021

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

An oral prodrug developed by a team of scientists led by Binghe Wang, Regents' Professor of Chemistry at Georgia State University, delivers carbon monoxide to protect against acute kidney injury, according to a new paper published in Chemical Science.

19 Jul 2021