Acute Respiratory Distress Syndrome News and Research

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Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

A team of scientists from the United States and Sweden has recently demonstrated that increased levels of a proinflammatory cytokine, angiopoietin-2, is responsible for hypercoagulation observed in severe COVID-19 patients.

18 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress s to expand the Phase II clinical trial at The University of Texas Health Science Center at HoustonQ.

13 Jan 2021

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

A recent study conducted by scientists from the Yokohama City University, Japan, has revealed that elevated alveolar endothelial injury markers in coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome (ARDS) are the main causative factors for alveolar barrier disruption. In COVID-19 patients with ARDS, endothelial injury persists for a longer time than epithelial injury.

12 Jan 2021

Boosting a natural cellular process could lower ventilator-related lung damage

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

12 Jan 2021

Headache as COVID-19 symptom could indicate milder disease, study finds

Researchers at the Hospital Universitario de La Princes in Madrid, Spain, found that patients with COVID-19 who developed headaches as an early symptom of infection had a milder illness and less risk of death.

12 Jan 2021

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2.

11 Jan 2021

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Diabetes is a known risk factor for morbidity and mortality related to COVID-19. In diabetes patients, rare but severe complications, like the potentially lethal condition diabetic ketoacidosis (DKA), can arise when illness or certain conditions prevent cells from receiving enough glucose to fuel their functioning.

28 Dec 2020

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

New project to develop a platform for monitoring microvascular health of COVID-19 patients

VASCOVID, a new European project, will develop a platform that uses near-infrared light to monitor microvascular health of COVID-19 patients and assist clinicians in delivering customized treatments.

23 Dec 2020

A real-time platform for monitoring microvascular health of COVID-19 patients in ICUs

As COVID-19 spread worldwide in early 2020, the avalanche of patients requiring admission into intensive care units (ICUs) suddenly became overwhelming to the healthcare systems.

21 Dec 2020

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

The first patient has enrolled in a Phase II clinical trial evaluating a stem cell therapy for the potential early treatment of traumatic injuries and their subsequent complications at The University of Texas Health Science Center at Houston.

21 Dec 2020

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

A new study, appearing as a preprint on the medRxiv* server, demonstrates the protective effect of drugs in older COVID-19 patients with hypertension.

21 Dec 2020

New report addresses the recovery of surgical services in post-pandemic

In 2013, the National Institute for Health Research (NIHR) established the GlobalSurg Collaborative, a network that has since grown to include more than 5,000 practicing surgeons from all corners of the planet.

21 Dec 2020

RedHill Biopharma announces promising preliminary results from opaganib study

TEL AVIV, Israel and RALEIGH, NC, December 15, 2020, RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced promising preliminary results from a preclinical study with opaganib.

15 Dec 2020

Pulmonary rehabilitation may promote recovery in severe COVID-19

A new study compares rehabilitation outcomes between COVID-19 patients and those with ordinary pneumonia, to evaluate the effectiveness of interventions.

11 Dec 2020

COVID-19 infection may also affect the central nervous system, cause neurological disorders

COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia

10 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

People with vitamin D deficiency at higher risk of severe COVID-19, says study

A new study has revealed that vitamin D deficient patients are more likely to experience severe COVID-19.

4 Dec 2020

Acute Respiratory Distress Syndrome News and Research

Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

Boosting a natural cellular process could lower ventilator-related lung damage

Headache as COVID-19 symptom could indicate milder disease, study finds

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Higher BMI linked to increased risk of SARS-CoV-2 infection

New project to develop a platform for monitoring microvascular health of COVID-19 patients

A real-time platform for monitoring microvascular health of COVID-19 patients in ICUs

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

New report addresses the recovery of surgical services in post-pandemic

RedHill Biopharma announces promising preliminary results from opaganib study

Pulmonary rehabilitation may promote recovery in severe COVID-19

COVID-19 infection may also affect the central nervous system, cause neurological disorders

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

People with vitamin D deficiency at higher risk of severe COVID-19, says study

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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