Acute Respiratory Distress Syndrome News and Research

RSS

Most people with COVID-19 develop symptoms, study says

A new study by researchers at the University of Bern and published in the journal PLOS Medicine reports that while some people never experience any symptoms, most of those infected with the novel coronavirus do develop symptoms.

23 Sep 2020

Bioinformatics analysis reveals genes and pathways shared in COVID-19 disease and comorbidities

Using bioinformatics approaches, researchers have identified genes and pathways shared among patients with comorbidities and having severe COVID-19. The research is published on the preprint server bioRxiv in September 2020.

23 Sep 2020

Children exhibit distinct immune system responses against COVID-19

Children and adults exhibit distinct immune system responses to infection by the virus that causes COVID-19, a finding that helps explain why COVID-19 outcomes tend to be much worse in adults, researchers from Yale and Albert Einstein College of Medicine report Sept. 18 in the journal Science Translational Medicine.

23 Sep 2020

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19.

22 Sep 2020

Study detects key differences in immune responses of adults and children with COVID-19

The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults.

22 Sep 2020

Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

Initial clinical guidelines for mechanical ventilation of COVID-19 patients suggested following standard approaches used in the treatment of acute respiratory distress syndrome (ARDS), which is characterized by rapid onset of widespread inflammation in the lungs.

21 Sep 2020

SARS-CoV-2 infects monocytes and macrophages, without cytopathic effect

A team of researchers from Aix-Marseille Univ, IHU-Méditerranée Infection, Institut Paoli Calmettes and Laboratoire d’Immunologie, Marseille, France, conducted experiments to determine if SARS-CoV-2 can affect the myeloid compartment or infect monocytes and macrophages.

20 Sep 2020

Key China COVID-19 study produced results that influenced subsequent research on coronavirus

Early in the onset of the COVID-19 pandemic, a small study in China produced results that influenced subsequent research on the virus.

18 Sep 2020

Biomarker predicts disease severity in COVID-19 patients

Airway cell analyses showing an activated immune axis could pinpoint the COVID-19 patients who will most benefit from targeted therapies.

17 Sep 2020

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

To predict severe outcome in COVID-19 patients, innate immune cellular signals are analyzed, identifying two novel neutrophil subsets: LOX-1- and CD123-expressing CD10-CD64+. Thromboembolic events correlated with high LOX-1 immature neutrophils – a potential prognostic signature.

17 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Researchers develop new PET imaging agent that spotlights inflammation

Many of the most common diseases -- cancer, diabetes, cardiovascular and lung disease, and even COVID-19 -- have been linked to chronic or excessive inflammation.

14 Sep 2020

Convalescent plasma fails to improve outcome of COVID-19 in India

A new study based in India and published on the medRxiv preprint server explores the role of convalescent plasma (CP) in the treatment of moderate COVID-19 within the limitations on resources faced in a developing country.

9 Sep 2020

Brain inflammation seen in fatal COVID-19 cases

Now, a new study by researchers at the Barts Health NHS Trust and the University of Cambridge in the United Kingdom shows that some patients develop neurological complications tied to COVID-19.

9 Sep 2020

Convalescent plasma could be an effective treatment for children with COVID-19

Early findings from researchers at Children's Hospital of Philadelphia (CHOP) show that convalescent plasma appears to be a safe and possibly effective treatment for children with life-threatening cases of COVID-19.

9 Sep 2020

Study addresses the role of macrophage activation syndrome in COVID-19

Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.

8 Sep 2020

Monitoring the activity of unconventional T cells could predict COVID-19 severity

Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells.

5 Sep 2020

CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

Study shows why coronavirus is more dangerous in people with comorbidities

Why is the COVID-19 virus more dangerous in people with comorbidities?. Sadis Matalon, Ph.D., of the University of Alabama at Birmingham and colleagues in Texas and San Francisco asked that question in a hypothesis paper published online in Physiological Reviews on March 27.

3 Sep 2020

Existing drug masitinib identified as potential inhibitor of SARS-CoV-2

Researchers in the United States have demonstrated that a drug originally developed as a treatment for cancer exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

2 Sep 2020

Acute Respiratory Distress Syndrome News and Research

Most people with COVID-19 develop symptoms, study says

Bioinformatics analysis reveals genes and pathways shared in COVID-19 disease and comorbidities

Children exhibit distinct immune system responses against COVID-19

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Study detects key differences in immune responses of adults and children with COVID-19

Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

SARS-CoV-2 infects monocytes and macrophages, without cytopathic effect

Key China COVID-19 study produced results that influenced subsequent research on coronavirus

Biomarker predicts disease severity in COVID-19 patients

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Researchers develop new PET imaging agent that spotlights inflammation

Convalescent plasma fails to improve outcome of COVID-19 in India

Brain inflammation seen in fatal COVID-19 cases

Convalescent plasma could be an effective treatment for children with COVID-19

Study addresses the role of macrophage activation syndrome in COVID-19

Monitoring the activity of unconventional T cells could predict COVID-19 severity

CRISPR-based system suppresses genes related to AAV antibody production

Study shows why coronavirus is more dangerous in people with comorbidities

Existing drug masitinib identified as potential inhibitor of SARS-CoV-2

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News