Acute Respiratory Distress Syndrome News and Research

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Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

Researchers conducted an umbrella review and meta-analysis of the RAAS inhibitors' impact on COVID-19 clinical outcomes.

23 Mar 2022

Coronavirus infection during pregnancy may double the risk of poor outcomes

A Kaiser Permanente analysis of pregnant patients who tested positive for the coronavirus found more than double the risk of poor outcomes including preterm birth, venous thromboembolism (blood clot), and severe maternal morbidity, which includes conditions such as acute respiratory distress syndrome and sepsis.

21 Mar 2022

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Researchers investigated whether small airway diseases are present following acute SARS-CoV-2 infection.

18 Mar 2022

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Researchers evaluated biomarkers that could help identify COVID-19 patients needing invasive mechanical ventilation.

17 Mar 2022

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.

17 Mar 2022

Study suggests expanding vaccination to children aged 5-11 would provide benefits to the US population

Researchers evaluated the impact of immunizing five-11-year-old children against SARS-CoV-2 on COVID-19 burden and resilience to new variants in the United States.

17 Mar 2022

Antimicrobial resistance in COVID-19

Researchers discuss the impact of this extensive use of antibiotics on the rise of antimicrobial resistance.

16 Mar 2022

Can cardiac biomarkers determine COVID-19 prognosis?

Researchers review prognostic cardiac biomarkers in COVID-19 patients.

15 Mar 2022

The effect of SARS-CoV-2 infection on patients with a history of atrial fibrillation

In a new study, scientists have evaluated if atrial fibrillation could be regarded as a comorbidity in relation to SARS-CoV-2 infection.

15 Mar 2022

Role of carboxypeptidase U in severe COVID-19

A new study measured both proCPU and CPU+CPUi over time to determine the impact of SARS-CoV-2 infection on the CPU system.

14 Mar 2022

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Researchers evaluated the survival benefit conferred by PLEX in patients with severe COVID-19 and cytokine-storm syndrome.

14 Mar 2022

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

A recent study was based on Mendelian randomization analyses conducted between high levels of numerous blood proteins and COVID-19.

9 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Patients with COVID-19-associated acute respiratory distress syndrome who received lung transplants had similar outcomes, compared to transplant patients without COVID-19, according to a Northwestern Medicine study published in JAMA.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Acute Respiratory Distress Syndrome News and Research

Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

Coronavirus infection during pregnancy may double the risk of poor outcomes

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Study suggests expanding vaccination to children aged 5-11 would provide benefits to the US population

Antimicrobial resistance in COVID-19

Can cardiac biomarkers determine COVID-19 prognosis?

The effect of SARS-CoV-2 infection on patients with a history of atrial fibrillation

Role of carboxypeptidase U in severe COVID-19

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

NETosis in COVID-19 and MIS-C

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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