Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

A new study introduces the possibility that the inactivated polio vaccine can elicit antibodies that inhibit SARS-CoV-2 nucleic acid synthesis.

10 Oct 2021

Phase I clinical trial of two Cuban recombinant protein COVID-19 vaccines

The results of Phase I clinical trials for two new COVID-19 vaccine candidates based on recombinant RDB proteins are reported.

10 Oct 2021

Oral and intranasal COVID-19 vaccines show promising results in hamster model

A new preprint discusses the protective effect of an oral adenovirus-vectored vaccine based on the SARS-CoV-2 spike against viral transmission and disease in hamsters.

8 Oct 2021

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

In this review, researchers summarized the therapeutic and pathogenic role of IL-7 in patients with COVID-19 and examined the promising role of IL-7 as a vaccine adjuvant.

7 Oct 2021

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

A new study reports on the results of phase III clinical trial on the safety and efficacy of the AstraZeneca-Oxford COVID-19 vaccine.

5 Oct 2021

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Glioblastoma is one of the deadliest cancers known to man. While the advent of immunotherapy and other cutting-edge treatments have prolonged life for people afflicted with other types of cancer, the prognosis for glioblastoma has remained relatively constant: just 18 months.

3 Oct 2021

Comparison of Pfizer, Moderna, J&J, AZ vaccines for neutralization titer, against Delta and other variants

Is one COVID vaccine better than the other? Four current vaccines — Moderna, Pfizer-BioNTech, Johnson & Johnson, and AstraZeneca — are highly effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but a new medRxiv* study suggests the level of protection varies.

30 Sep 2021

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

An observational study compares immune responses against three vaccines.

29 Sep 2021

Trial of Sanofi/GSK SARS-CoV-2 vaccine boosters against variants in non-human primates

New research discusses the development of soluble prefusion-stabilized spike trimers (CoV2 preS dTM) comprising adjuvant AS03.

27 Sep 2021

Factors predicting vaccine hesitancy in India

A recent study discusses vaccine hesitancy in India, which is one of the most populous countries in the world.

26 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

DNA sensor can detect infectious viruses in minutes

A new sensor can detect not only whether a virus is present, but whether it's infectious – an important distinction for containing viral spread.

23 Sep 2021

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A new study utilized MVA to develop vaccine candidates that were subsequently evaluated in animal models of congenital cytomegalovirus disease.

19 Sep 2021

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

In a study available on the preprint server medRxiv*, researchers have created a vaccine designed to overcome issues associated with attenuated-virus vaccines.

17 Sep 2021

New vaccine platform can better induce anti-malaria immunity in the liver

Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver.

16 Sep 2021

How effective is the Johnson & Johnson COVID-19 vaccine?

A new study demonstrates the real-world efficacy of this vaccine, its stability over time, as well as its efficacy against the SARS-CoV-2 Delta variant.

16 Sep 2021

Reproductive specialist highlights the need to investigate menstrual changes after covid-19 vaccination

Some women say their periods change after getting a covid-19 vaccination. In The BMJ today, Dr Victoria Male, a reproductive specialist at Imperial College London, says a link between menstrual changes after covid-19 vaccination is plausible and should be investigated.

16 Sep 2021

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

How effective are COVID-19 vaccines against mild and severe disease?

A new paper in the New England Journal of Medicine reports on the effectiveness of the COVID-19 vaccines in a healthcare setting.

14 Sep 2021

New method for profiling tissue-specific secretory proteins in live mice

Researchers have presented a method for profiling tissue-specific secretory proteins in live mice. This method is expected to be applicable to various tissues or disease models for investigating biomarkers or therapeutic targets involved in disease progression.

14 Sep 2021

Adenovirus News and Research

Further Reading

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

Phase I clinical trial of two Cuban recombinant protein COVID-19 vaccines

Oral and intranasal COVID-19 vaccines show promising results in hamster model

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Comparison of Pfizer, Moderna, J&J, AZ vaccines for neutralization titer, against Delta and other variants

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

Trial of Sanofi/GSK SARS-CoV-2 vaccine boosters against variants in non-human primates

Factors predicting vaccine hesitancy in India

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

DNA sensor can detect infectious viruses in minutes

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

New vaccine platform can better induce anti-malaria immunity in the liver

How effective is the Johnson & Johnson COVID-19 vaccine?

Reproductive specialist highlights the need to investigate menstrual changes after covid-19 vaccination

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

How effective are COVID-19 vaccines against mild and severe disease?

New method for profiling tissue-specific secretory proteins in live mice

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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