Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers-;some of the deadliest kinds of cancer-; have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Co-circulation of respiratory viruses during the SARS-CoV-2 Alpha surge

Recently, scientists evaluated the influence of mitigation measures that were originally implemented to restrict COVID-19 transmission, on other respiratory viruses.

16 Jun 2022

Co-circulation of adenovirus 40/41 and SARS-CoV-2 and emergence of hepatitis cases in children

In a recent study posted to the medRxiv* pre-print server, KU Leuven researchers investigated whether there was an association between the intensity of the co-circulation of adenovirus (AdV) 40/41 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the number of hepatitis cases of unknown origin emerging in Belgium.

12 Jun 2022

Can dogs accurately detect COVID-19?

Researchers evaluate the accuracy of using dogs to smell and identify the presence of SARS-CoV-2 in infected and non-infected individuals.

6 Jun 2022

Pneumonia frequency and severity found to be lower in patients with full COVID-19 vaccination

According to ARRS' American Journal of Roentgenology (AJR), evaluating chest CT findings offers an additional approach for demonstrating the efficacy of different COVID-19 vaccines in reducing the impact of a COVID-19 diagnosis.

1 Jun 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Largest study to date on the effect of vaccination on long-COVID

In a recent study published in the British Medical Journal, researchers evaluated the association between coronavirus disease 2019 (COVID-19) vaccination and long COVID symptoms among adults residing in United Kingdom (UK) communities with positive COVID-19 history before vaccination.

23 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Update: CDC continues to identify and investigate hepatitis of unknown cause impacting children

The Centers for Disease Control and Prevention (CDC) continues to work with health departments and clinicians nationwide to identify and investigate hepatitis of unknown cause impacting children.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Study investigates COVID-19 vaccination in pregnancy

A new study discusses the risk of COVID-19-related complications in pregnancy and the role of vaccination in reducing this risk.

17 May 2022

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

Researchers observed that the SARS-CoV-2 Omicron BA.2 variant is immunologically different from other variants, including Omicron BA.1.

16 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

A new study analyzed the imprinted antibody responses towards the SARS-CoV-2 Omicron subvariants.

12 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

A recent article published in Science Translational Medicine demonstrated that mucosally delivered adenovirus type 5 (Ad5)-based COVID-19 vaccination minimized COVID-19 transmission and severity.

9 May 2022

Adenovirus News and Research

Further Reading

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Co-circulation of respiratory viruses during the SARS-CoV-2 Alpha surge

Co-circulation of adenovirus 40/41 and SARS-CoV-2 and emergence of hepatitis cases in children

Can dogs accurately detect COVID-19?

Pneumonia frequency and severity found to be lower in patients with full COVID-19 vaccination

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

Largest study to date on the effect of vaccination on long-COVID

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Update: CDC continues to identify and investigate hepatitis of unknown cause impacting children

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Study investigates COVID-19 vaccination in pregnancy

SARS-CoV-2 Omicron BA.2 differs antigenically from previous variants

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

Imprinted antibody responses towards SARS-CoV-2 Omicron subvariants

Discovery of host co-factors necessary for SARS-CoV2 infection

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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