Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Researchers investigated the cases of severe hepatitis of unknown etiology in young children who presented to the hospital between 14 March and 4 April 2022 in Scotland.

28 Jul 2022

Incorporating a coronavirus antigen into MMR vaccine to produce COVID-19 immunity in kids

New research has advanced COVID-19 vaccine work in several ways: using a modified live attenuated mumps virus for delivery, showing that a more stable coronavirus spike protein stimulates a stronger immune response, and suggesting a dose up the nose has an advantage over a shot.

27 Jul 2022

Study estimates prevalence of SARS-CoV-2 omicron breakthrough infections in South Africa

Scientists have described the prevalence of vaccine breakthrough SARS-CoV-2 infection in South Africa during the period of delta and omicron circulation.

27 Jul 2022

SARS-CoV-2 oral vaccine candidate found to induce neutralizing mucosal IgA

A new study reported the outcomes of a clinical trial evaluating the oral vaccine candidate against SARS-CoV-2 developed by Vaxart.

25 Jul 2022

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

Cancers in humans have all sorts of ways to survive and thrive: Cells and tumors alike engage in devious means to deflect, deceive, and evade detection by our bodies’ immune systems.

20 Jul 2022

Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length

Investigators analyzed the connections between SARS-CoV-2 vaccination and infection with menstrual health.

18 Jul 2022

How does hybrid immunity shape humoral immune response to SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers illustrated that hybrid severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity widens effective humoral signatures of SARS-CoV-2 vaccinations.

6 Jul 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers-;some of the deadliest kinds of cancer-; have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Co-circulation of respiratory viruses during the SARS-CoV-2 Alpha surge

Recently, scientists evaluated the influence of mitigation measures that were originally implemented to restrict COVID-19 transmission, on other respiratory viruses.

16 Jun 2022

Co-circulation of adenovirus 40/41 and SARS-CoV-2 and emergence of hepatitis cases in children

In a recent study posted to the medRxiv* pre-print server, KU Leuven researchers investigated whether there was an association between the intensity of the co-circulation of adenovirus (AdV) 40/41 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the number of hepatitis cases of unknown origin emerging in Belgium.

12 Jun 2022

Can dogs accurately detect COVID-19?

Researchers evaluate the accuracy of using dogs to smell and identify the presence of SARS-CoV-2 in infected and non-infected individuals.

6 Jun 2022

Pneumonia frequency and severity found to be lower in patients with full COVID-19 vaccination

According to ARRS' American Journal of Roentgenology (AJR), evaluating chest CT findings offers an additional approach for demonstrating the efficacy of different COVID-19 vaccines in reducing the impact of a COVID-19 diagnosis.

1 Jun 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Largest study to date on the effect of vaccination on long-COVID

In a recent study published in the British Medical Journal, researchers evaluated the association between coronavirus disease 2019 (COVID-19) vaccination and long COVID symptoms among adults residing in United Kingdom (UK) communities with positive COVID-19 history before vaccination.

23 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Update: CDC continues to identify and investigate hepatitis of unknown cause impacting children

The Centers for Disease Control and Prevention (CDC) continues to work with health departments and clinicians nationwide to identify and investigate hepatitis of unknown cause impacting children.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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