Adipose News and Research

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New method for detecting breast cancer at 'stage 0'

RNL Natural Co., Ltd, a leading biotech company specialized in adult stem cell therapeutics affiliated with RNL BIO Co., Ltd., introduced on June 22, 2011 a new method of detecting breast cancer as early as at 'stage 0' through breath VOCs.

25 Jul 2011

Scientists directly link lipid metabolism and cancer-associated cachexia

Scientists from Graz, Austria, have now directly linked lipid metabolism and cancer-associated cachexia. Science reports via its online channel Science Express that mice deficient in the lipid degrading enzyme Adipose Triglyceride Lipase (ATGL) are fully protected against cancer-associated cachexia.

22 Jul 2011

Promising compounds for new anti-obesity drugs

Though it generally is known that obesity dramatically increases the risk for type 2 diabetes, the biological mechanisms for that connection still are unclear.

21 Jul 2011

Solution for treating obesity-related diseases may reside in fat tissue

Researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have shown that the quality – not just the quantity – of adipose, or fat, tissue is a significant contributing factor in the development of inflammation and vascular disease in obese individuals. The study, which is a special feature on the iPAD version of the Journal of the American College of Cardiology, provides compelling evidence that the answer to treating cardiovascular disease and other obesity-related disorders, such as type 2 diabetes and cancer, might be found in the adipose tissue itself.

7 Jul 2011

New biological insights into fat tissue

For better or worse, a popular class of anti-diabetic drugs does more than lower blood sugar. One known as rosiglitazone has been in the spotlight for its possible link to increased cardiovascular events, but it also seems to come with unexplained vascular benefits and an unwelcome tendency for weight gain.

6 Jul 2011

Adipose tissue might serve as target for treating obesity-related disorders

Researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have shown that the quality - not just the quantity - of adipose, or fat, tissue is a significant contributing factor in the development of inflammation and vascular disease in obese individuals.

5 Jul 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011

Experts discuss therapeutic potential of adipose-derived stem cells at ICAS Conference

Esthetic therapies with stem cells from autologous fat are revolutionizing cosmetic surgery: Ever more women prefer breast augmentations with autologous stem cells over silicone implants. The world's leading experts recently met at the ICAS Conference in Istanbul to discuss the therapeutic potential of stem cells from fat tissue.

28 Jun 2011

New data from Zafgen's ZGN-433 Phase 1b study on obesity presented at ADA 2011

Zafgen, Inc., a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced new data from a Phase 1b study of ZGN-433, a selective methionine aminopeptidase 2 inhibitor (MetAP2), which showed a significant improvement in cardiovascular risk markers in severely obese subjects.

27 Jun 2011

Innovative adult stem cell approach could help eliminate obesity

Innovative adult stem cell research by scientists at The University of Texas Health Science Center at Houston could aid efforts to apply the brakes to stem cells that produce the type of fat ringing the waists of millions. Research appeared today online ahead of the print issue of Cell Stem Cell.

17 Jun 2011

Key to remove stem cells responsible for fat expansion

Researchers may have found the key to developing a method to rid the body of stem cells responsible for driving fat expansion. According to a report in the June 16 Cell Stem Cell, a Cell Press publication, they've landed the first protein marker on the surface of those so-called adipose stromal cells (ASCs), which serve as progenitors of the cells that make up fat tissue.

17 Jun 2011

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

The mechanisms by which obesity leads towards metabolic co-morbidities, such as diabetes mellitus, are poorly understood and of great public health interest. A study led by Matej Orešič from VTT Technical Research Centre of Finland suggests that adaptation of fat cell membranes to obesity may play a key role in the early stages of inflammatory disorders.

10 Jun 2011

Adipose-derived stem cell procedure restores skull defects after brain surgery

Stem cells derived from abdominal fat—used along with a synthetic bone grafting material—are a potentially valuable new approach to repairing skull defects after brain surgery, according to a study in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

2 Jun 2011

GE Healthcare receives FDA 510k clearance for CoreScan to treat obesity-related disease

GE Healthcare today announced 510k clearance of CoreScan - a widely-accessible application dedicated to quickly and accurately quantifying visceral adipose tissue, or visceral "belly" fat, during body composition analysis.

26 May 2011

Key U.S. patents increase commercial rights and clinical indications

Australian regenerative medicine company, Mesoblast Limited (ASX:MSB; OTC ADR: MBLTY), today announced that the company’s product development strategy has been significantly strengthened by novel composition of matter claims granted by the United States Patent and Trade Mark Office (USPTO) in two distinct patent families to which Mesoblast has exclusive worldwide commercial rights.

23 May 2011

Cytori Therapeutics announces independent clinical study results in breast reconstruction presented at the Association of Breast Surgery conference

Cytori Therapeutics, Inc. (NASDAQ: CYTX) reports that surgeons from North Tees and Hartlepool NHS Foundation Trust have presented clinical outcomes using Adipose-Derived Regenerative Cell (ADRC) fat grafting in reconstructive breast surgery at the Association of Breast Surgery Conference in Manchester, UK, May 16-17, 2011. The procedure, referred to by Cytori as RESTORE, was separately investigated in Cytori’s own RESTORE 2 trial.

17 May 2011

Scientists decipher how hair stem cells can communicate with each other

In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles - as opposed to the stem cell of a single hair follicle - Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article published in the April 29 edition of the journal Science.

10 May 2011

Breakthrough research offers hope for new obesity treatment

By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.

4 May 2011

Fat stem cells may help develop new regenerative therapies for cardiovascular disease

Stem cells extracted from body fat may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered cartilage or bone, and the treatment of cardiovascular disease.

4 May 2011

Study examines racial differences between obesity and vitamin D among children

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that while black and white children with vitamin D deficiency both had higher fat levels, black children were more likely to have higher levels of fat just under their skin and white children were more likely to have higher levels of fat between their internal organs.

28 Apr 2011