Airway Inflammation News and Research

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Unhealthy diet and lifestyle linked to childhood asthma - study

Asthma in children is on the rise worldwide and scientists have often blamed the environment for this trend. Britain has more than 1.1 million children and the US has nearly 10 million children with asthma. In a new international study diet has been cited to be a factor that affects asthma in children. The study on Allergies and Asthma in Childhood has shown what many parents knew for a while now – burgers are not good for children.

3 Jun 2010

Asthma patients need to avoid heavy, high-fat meals: New research

People with asthma may be well-advised to avoid heavy, high-fat meals, according to new research. Individuals with asthma who consumed a high-fat meal showed increased airway inflammation just hours after the binge, according to Australian researchers who conducted the study.

17 May 2010

Novel internet-based strategy effective in patients with severe prednisone dependent asthma

Patients with severe asthma who use an internet-supported strategy and daily monitoring of exhaled nitric oxide were able to control their asthma with lower overall dosing of oral corticosteroids than patients who underwent usual care, according to research from the Netherlands.

17 May 2010

Female sex hormones may work with estrogen in reducing airway constriction: Research

Female sex hormones may work with beta-agonists in reducing airway constriction, according to new bench research from the Mayo Clinic.

17 May 2010

First case of treating cystic fibrosis and Crohn's disease with infliximab

Cystic fibrosis (CF) is the most common life-threatening autosomal recessive disease in Caucasian children; it has an incidence of 1 case in every 2500 children born alive. CF involves an anomalous function of the exocrine glands, caused by a mutation of a gene (cystic fibrosis transmembrane conductance regulator, CFTR) located on chromosome 7, which codes for a protein involved in ion transport through the cell membrane.

20 Apr 2010

Update on Aerocrine AB's patent infringement cases against Apieron

Aerocrine AB today announced that its patent infringement cases in the U.S. and Europe against Apieron Inc., Menlo Park, USA will be stayed as a result of Apieron filing for Chapter 7 bankruptcy.

7 Apr 2010

JACI supplement supports the importance of small airways in asthma management

Increasing evidence supports the importance of small airways in the diagnosis and treatment of asthma; however, focused areas of discussion and critical review of this topic have been lacking. To foster a better understanding of the role of small airways in asthma management, Teva Respiratory, a subsidiary of Teva Pharmaceutical Industries Ltd., will be providing reprints of a special supplement entitled "Small Airway Involvement: A Key to Asthma" from the December issue of the Journal of Allergy and Clinical Immunology at their exhibit (Booth #724) at the American Academy of Allergy, Asthma & Immunology Annual Meeting being held Feb. 26-March 2, 2010 in New Orleans, La.

1 Mar 2010

FDA's warning over LABA medications for asthma: AANMA offers guidance

Today Allergy & Asthma Network Mothers of Asthmatics (AANMA) offered guidance to help patients understand recent Food and Drug Administration (FDA) warnings about Advair ® (fluticasone and salmeterol), Foradil ® (formoterol), Severent ® (salmeterol) and Symbicort ® (budesonide and formoterol), daily inhaled medications containing a long-acting beta agonist (LABA, a 12-hour bronchodilator).

24 Feb 2010

Cephalon to acquire Ception Therapeutics following positive clinical study of eosinophilic asthma

Cephalon, Inc. (Nasdaq: CEPH) announced today that it has exercised its option to acquire Ception Therapeutics, Inc., following receipt of positive data from a clinical study in adults with eosinophilic asthma.

23 Feb 2010

Gene's role in immune system may suggest new treatments for childhood asthma

Pediatric researchers have identified a novel gene involved in childhood asthma, in one of the largest gene studies to date of the common respiratory disease. Because the gene, called DENND1B, affects cells and signaling molecules thought to be instrumental in the immune system overreaction that occurs in asthma, the discovery may have singled out an important target for new treatments.

23 Dec 2009

Altair Therapeutics initiates its IL-4 receptor alpha inhibitor bronchoprovocation phase 2 trial

Altair Therapeutics, Inc., a privately-held, biopharmaceutical company developing novel therapeutics for respiratory diseases, today announced the commencement of its IL-4 receptor alpha inhibitor bronchoprovocation trial. Study AIR645-CS2 is a phase 2, multi-center, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, and efficacy of inhaled AIR645 in suppressing the asthmatic response in subjects with mild asthma. Results are expected in the third quarter of 2010.

19 Nov 2009

Oral contraceptives may have a potential role in the management of premenopausal women with asthma

New research shows that during natural menstrual cycles, women with asthma who were not taking oral contraceptives (OC) had lower exhaled nitric oxide levels (eNO), a marker of airway inflammation associated with asthma, than women who were taking OC.

5 Nov 2009

Aerocrine, PSEC enters into a long-term development agreement

Aerocrine AB today announced that Aerocrine and Panasonic Shikoku Electronics, CO., LTD (PSEC) have entered into a long-term agreement to develop, manufacture and market new generation products for airway inflammation monitoring using exhaled nitric oxide.

4 Nov 2009

Aerocrine’s NIOX MINO technology approved in Canada for treating asthma

Aerocrine AB (STO:AEROB) today announced that Health Canada’s Therapeutic Products Directorate has approved Aerocrine’s NIOX MINO® technology for use in treating asthma. Canada’s National Health Service may now begin using the NIOX MINO, a medical device that provides a measure of the degree of inflammation in the airways in a single breath.

3 Sep 2009

Exhaled nitric oxide needs to be measured in asthma patients

CareFirst BlueCross BlueShield, the largest health care insurer in the Mid-Atlantic region of the USA, has adopted a policy stating that measurement of exhaled nitric oxide (eNO) is considered medically necessary in the management of asthma patients.

21 Aug 2009

Aerocrine allowed to add a third patent to its infringment complaint against Apieron

Aerocrine AB today announced that the United States District Court has accepted Aerocrine’s motion for leave to add a third patent to its October 2008 patent infringement complaint against Apieron, Inc. Menlow Park, USA.

19 Aug 2009

Aldose reductase inhibition shows promise for asthma

University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks - and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.

11 Aug 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition.

2 Apr 2009

Statins reduce odds of an asthma-related hospitalization or ER visit

Results of a new study presented at the 2009 Annual Meeting of the American Academy of Asthma, Allergy and Immunology (AAAAI) show dramatic reductions in emergency room (ER) visits and hospitalizations for asthma patients taking cholesterol-lowering statins in addition to common asthma treatments.

15 Mar 2009

Patients with severe asthma benefit from injections of the antibody, mepolizumab

McMaster University researchers have found patients with a very severe asthma benefit from injections of the antibody, mepolizumab.

4 Mar 2009

Airway Inflammation News and Research

Unhealthy diet and lifestyle linked to childhood asthma - study

Asthma patients need to avoid heavy, high-fat meals: New research

Novel internet-based strategy effective in patients with severe prednisone dependent asthma

Female sex hormones may work with estrogen in reducing airway constriction: Research

First case of treating cystic fibrosis and Crohn's disease with infliximab

Update on Aerocrine AB's patent infringement cases against Apieron

JACI supplement supports the importance of small airways in asthma management

FDA's warning over LABA medications for asthma: AANMA offers guidance

Cephalon to acquire Ception Therapeutics following positive clinical study of eosinophilic asthma

Gene's role in immune system may suggest new treatments for childhood asthma

Altair Therapeutics initiates its IL-4 receptor alpha inhibitor bronchoprovocation phase 2 trial

Oral contraceptives may have a potential role in the management of premenopausal women with asthma

Aerocrine, PSEC enters into a long-term development agreement

Aerocrine’s NIOX MINO technology approved in Canada for treating asthma

Exhaled nitric oxide needs to be measured in asthma patients

Aerocrine allowed to add a third patent to its infringment complaint against Apieron

Aldose reductase inhibition shows promise for asthma

Discovery of gene that modifies severity of cystic fibrosis lung disease

Statins reduce odds of an asthma-related hospitalization or ER visit

Patients with severe asthma benefit from injections of the antibody, mepolizumab

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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