Airway Inflammation News and Research

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Ikaria's INOmax approved in Australia

Ikaria Holdings, Inc., through its subsidiary INO Therapeutics LLC, announced today that it has received approval from Australia's regulatory body, the Therapeutic Goods Administration (TGA), for INOmax (nitric oxide) for inhalation.

27 Nov 2007

Breastfed babies breathe better, except when mother is asthmatic

When it comes to feeding babies, the old adage "breast is best" certainly holds true, with breastfed babies having less diarrhea and fewer ear infections and incidents of wheezing in early life.

2 Nov 2007

Chitin compound causes allergic inflammation

The beetle's back and the crab's shell owe their toughness to a common compound called chitin that now appears to trigger airway inflammation and possibly asthma, UCSF scientists have found.

24 Apr 2007

Taming chronic cough

Chronic cough – often causing much discomfort, frustration, irritability and sleep disturbances in 10 percent to 20 percent of adults – is one of the leading reasons for consultation with a physician according to a report published this month in Annals of Allergy, Asthma & Immunology , the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

21 Apr 2007

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

A new review suggests that asthma treatment based on tests of fluid coughed up from the lungs could reduce the frequency and severity of flare-ups in adult asthma patients.

19 Apr 2007

Weak immune response critical to disease that causes most infant hospitalizations

The most common cause of infant hospitalization in the United States, respiratory syncytial virus, infects virtually all children by age two.

7 Apr 2007

Inhaled corticosteroids deserve further consideration for lung cancer chemoprevention

Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer.

4 Apr 2007

Childhood asthma linked to low vitamin E intake during pregnancy

Researchers in Britain believe that children whose mothers had a low intake of vitamin E during pregnancy are more likely to develop wheezing and asthma by age five.

4 Sep 2006

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

Asthma rates are rapidly increasing, particularly in children. Although asthma is mediated in part by activation of special immune cells called Th2 cells, the precise causes are unclear.

7 Mar 2006

Fish oil shown to reduce airway inflammation caused by exercise-induced asthma

People suffering from exercise-induced asthma were able to reduce their symptoms below the threshold used to diagnose the disease by eating a diet supplemented with fish oil, according to new research findings from Indiana University reported in the January issue of the journal Chest.

10 Jan 2006

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Allergists help manage asthma better

Compared to patients receiving care from primary care physicians, asthma patients who are under the care of an allergist report fewer asthma control problems and less sever asthma symptoms, according to new research in the December 2005 Journal of Allergy & Clinical Immunology (JACI).

20 Nov 2005

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

The study by Bucala and his colleagues in Dublin, Ireland, included experiments in mice that are resistant to developing asthma because they lack the gene, and an examination of a human population in Dublin chosen for their similar ethnic and geographic identity.

20 Sep 2005

Discovery that oxidative stress from pollen is as important as antigen exposure could lead to new therapies

For a person with allergies or asthma, breathing in pollen can be a very bad thing. Within minutes of inhalation by someone sensitive to their effects, these tiny particles can trigger severe inflammation of the respiratory passages, producing uncontrollable sneezing, coughing, or extreme shortness of breath -- symptoms agonizingly familiar to those who suffer from allergy and asthma attacks.

1 Aug 2005

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Carbon monoxide, a poisonous gas that kills thousands of Americans every year, could turn out to be a life-saver for patients recovering from organ transplants, strokes or heart attacks, according to new research from the University of Michigan Cardiovascular Center.

28 Jul 2005

Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma

A research team led by Shyam Biswal , PhD, at the Johns Hopkins Bloomberg School of Public Health found the absence of Nrf2 exacerbated allergen-mediated asthma in mice models.

5 Jul 2005

Risk of lung cancer increased by poor lung function

People with poor lung function are at an increased risk of developing lung cancer, suggests a study in Thorax.

1 Jul 2005

Modifying your salt intake has the potential to prevent exercise-induced asthma

An Indiana University professor may have uncovered the mechanisms by which high-salt diets can trigger exercise-induced asthma, offering the most complete picture to date of how dietary factors can both aggravate and alleviate the symptoms of this common condition.

9 Jun 2005

Airway inflammation boosts infarction damage

Epidemiological studies show that the incidence of cardiovascular disease (CVD) complications are increased in long standing cases of asthma. Historically, the complications are often attributed to the chronic drug therapy used to treat asthma.

3 Apr 2005

Racial differences may play a significant role in determining a patient's response to asthma medications

A new study in the February issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), shows that asthmatic and nonasthmatic African-Americans required higher doses of glucocorticoids to suppress lymphocytes, which play an important role in airway inflammation.

7 Feb 2005