Aldosterone News and Research

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Aldosterone is a steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body. Too much aldosterone can cause high blood pressure and a build-up of fluid in body tissues. Aldosterone is a type of mineralocorticoid hormone.

Hormone aldosterone linked to high blood pressure and blood vessel disease in African Americans

Researchers at The Medical College of Wisconsin in Milwaukee have linked higher levels of the hormone aldosterone to high blood pressure and blood vessel disease in African Americans.

17 Feb 2009

Candesartan cilexetil reduces proteinuria in kidney disease patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology ( JASN ).

11 Feb 2009

Seasonal variation in blood pressure

A French study reported in the 12th January issue of Archives of Internal Medicine has found a strong correlation between blood pressure and outdoor temperature in a large sample of the elderly.

19 Jan 2009

Treatment fails to improve common form of heart failure

A medication used for high blood pressure does not improve a common form of heart failure, according to new results from a large, international study.

5 Dec 2008

Study finds medication fails to improve common form of heart failure

A medication used for high blood pressure does not improve a common form of heart failure, according to new results from a large, international study.

5 Dec 2008

Treatment with irbesartan fails to improve common form of heart failure

A medication used for high blood pressure does not improve a common form of heart failure, according to new results from a large, international study.

4 Dec 2008

Vitamin D deficiency could lead to heart problems

Vitamin D deficiency - which is traditionally associated with bone and muscle weakness - may also increase the risk of cardiovascular disease (CVD).

1 Dec 2008

New therapy for heart failure

During heart failure the body reacts to the production of the hormone aldosterone. Too much aldosterone can stiffen and damage the muscles of the heart.

15 Oct 2008

Blood pressure response to daily stress provides clues for better hypertension treatment

How the body regulates blood pressure in response to daily stress is the focus of a study geared toward helping people whose pressure is out of control.

14 Aug 2008

Discovery of master switch that regulates blood pressure

A team of Oregon Health & Science University researchers studying a rare form of hypertension has identified the mechanism by which they believe a protein complex in the kidney operates as a master switch that regulates blood pressure, a finding that has broad implications for the treatment of more common forms of hypertension.

2 Nov 2007

Gene-drug interactions that lower blood pressure

Patients with high blood pressure respond very differently to antihypertensive medication, making treatment selection tricky for physicians.

13 Sep 2007

The first clinically available oral direct renin inhibitor shows promise in heart failure

Drugs that block a hormonal cascade, known as the renin-angiotensin-aldosterone system (RAAS), help patients with heart failure. Direct renin inhibitors (DRIs) block the RAAS at its first and rate-limiting step.

2 Sep 2007

Are there gender differences in management modalities?

There are major differences in the risk profile and characteristics of female patients treated for acute heart failure. Female patients are underrepresented in management trials on Heart Failure. According to data from the Euro Heart Survey on acute Heart Failure 2004-2005 in Europe, however, medical treatment has improved.

2 Sep 2007

Hypertension in African Americans - forthcoming study will look at how genes can contribute to hypertension

Exercise cannot reduce a sodium-retaining hormone in African Americans known to potentially cause hypertension, found Michael D. Brown, Ph.D., the senior author of a study in the September issue of Experimental Physiology. Brown is an associate professor of kinesiology at Temple University's College of Health Professions.

17 Aug 2007

Lack of sleep leads to increased urinary output and more salt in urine

Our body's production of urine follows a circadian rhythm. During the day, we experience greater urinary frequency; at night, urine production declines, enabling us to get uninterrupted sleep.

9 Aug 2007

Initiative to improve heart failure care at nation's hospitals makes major gains

A national initiative designed to improve heart-failure patient care in hospitals proved effective at increasing hospital adherence to key quality-of-care performance measures and reducing the length of hospital stays for patients.

24 Jul 2007

Low potassium levels linked to increased mortality in heart failure patients

New research from University of Alabama at Birmingham indicates that patients with heart failure who have low to low-normal serum potassium levels are at increased risk of death.

8 Jun 2007

New treatments and interventions for chronically impaired cardiac patients

Whether a patient is awaiting a heart transplant or living with chronic heart failure, cardiologists are continuously looking for new therapies that address short-term and/or long-term needs of chronically impaired cardiac patients.

30 Mar 2007

Immunotherapy for heart failure

World Congress of Cardiology Report - Heart failure (HF) is a complex, progressive clinical syndrome that can result from any structural or functional cardiac disorder, such as coronary artery disease or hypertension (high blood pressure), which impairs the ability of the heart to function properly as a pump.

5 Sep 2006

Scientists reconstruct Darwinian evolution to explain 'irreducible complexity'

Using new techniques for resurrecting ancient genes, scientists have for the first time reconstructed the Darwinian evolution of an apparently "irreducibly complex" molecular system.

11 Apr 2006