Amyloid Plaque News and Research

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Molecular imaging helps follow the progression of Alzheimer's disease

In the past, physicians were able only to follow the progression of Alzheimer's disease (AD) through careful clinical histories, noting the often subtle changes associated with cognitive decline over a number of years.

16 Jun 2008

ExpIND process speeds Alzheimer's drug research

Researchers are actively cutting the time and cost it normally takes to develop radiopharmaceuticals by taking advantage of "Exploratory Investigational New Drug" (ExpIND), an FDA-sanctioned procedure that enhances post-discovery drug development while observing scientific and patient safety standards.

16 Jun 2008

Australian researchers find important piece of Alzheimer's puzzle

Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer's disease.

11 Jun 2008

Genetic variation linked to earlier onset of Alzheimer's symptoms

Investigators at Washington University School of Medicine in St. Louis have identified a genetic variation associated with an earlier age of onset in Alzheimer's disease.

9 Jun 2008

Yale researchers block transforming growth factor to clear up amyloid plaques in mice

Blocking a common immune system response cleared up plaques associated with Alzheimer's Disease and enabled treated mice to recover some lost memory, Yale University researchers report Friday in the journal Nature Medicine.

1 Jun 2008

Rochester vaccine triggers immune response, prevents Alzheimer's

A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.

19 May 2008

Patent claims allowed covering Samaritan's Alzheimer's memory recovery drug in Australia

Samaritan Pharmaceuticals, a biopharmaceutical company committed to commercializing new innovative therapeutic drugs, has received notification that the claims in the patent application for "Neuroprotective Spirostenol Pharmaceutical Compositions" covering Caprospinol (SP-233) have been allowed by the Australian Patent Office.

6 May 2008

Discovery of molecular link between Alzheimer's disease and amyloid plaques

According to estimates there are 85,000 Alzheimer patients in our country and approximately 20,000 new cases every year. This spectacular increase is due to the increasing ageing population. Unfortunately it is still unclear precisely which ageing process forms the basis of this spectacular rise in the occurrence of the disease.

22 Apr 2008

2nd Alzheimer's vaccine by AFFiRiS

The Viennese biotech company Affiris is today taking stock of the progress achieved to date in its clinical Alzheimer's vaccination programme. All the Alzheimer's patients treated so far as part of the toxicological trials have tolerated the treatment extremely well. As a result, Affiris is among the leading international centres in the race to develop the first causal immunotherapy for Alzheimer's disease.

17 Apr 2008

Alzheimer's vaccine clears amyloid plaques but has little effect on learning and memory impairment

A promising vaccine being tested for Alzheimer's disease does what it is designed to do -- clear beta-amyloid plaques from the brain -- but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study.

7 Apr 2008

Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease

Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated with Alzheimer's disease, a new study in a mouse model of this currently untreatable neurodegenerative condition reports.

28 Mar 2008

Groundbreaking study validates Pittsburgh Compound-B in identifying Alzheimer's disease brain toxins

A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease researchers reported in the journal Brain (currently online) confirms that Pittsburgh Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of patients with Alzheimer's disease.

28 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

20 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

17 Mar 2008

Paradoxical Alzheimer's finding may provide better understanding of memory loss

Do you remember the seventh song that played on your radio on the way to work yesterday?

10 Mar 2008

Moss protein plays role in Alzheimer's disease

Preventing Alzheimer's from developing is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine.

11 Feb 2008

Microscopic imaging technique reveals rapid formation of Alzheimer's-associated plaques

The amyloid plaques found in the brains of Alzheimer's disease patients may form much more rapidly than previously expected.

7 Feb 2008

New method for measuring protein synthesis

In a major breakthrough for future research and drug development, a team of Los Angeles Biomedical Research Institute (LA BioMed) investigators developed a new, more reliable method for measuring protein synthesis and turnover, processes that are critical to understanding cellular functions.

23 Jan 2008