Amyloid Plaque News and Research

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What do gut microbiota have to do with Alzheimer's and dementia?

Researchers explore the preventive and therapeutic potential of gut microbiome modulation in the treatment of Alzheimer’s disease.

6 Feb 2023

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

A new study discusses the impact of several human viruses on blood-brain barrier function and insulin sensitivity.

31 Jan 2023

New blood test tracks neurodegenerative changes specifically in Alzheimer's disease

A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.

16 Jan 2023

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

Quanterix’s Simoa® technology drives advances in Alzheimer’s disease research presented at 2022 Clinical Trials On Alzheimer’s Disease (CTAD) conference

Quanterix Corporation, a company fueling scientific discovery through ultrasensitive biomarker detection, today announced that its Simoa® technology has powered important advances in ongoing clinical trials for the treatment of Alzheimer’s disease (AD). The findings were presented at the 15th Clinical Trials on Alzheimer’s Disease (CTAD) conference held in San Francisco, CA from November 29 to December 2, 2022.

From Quanterix 12 Dec 2022

Study: People with higher levels of vitamin D in the brain have better cognitive function

An estimated 55 million people worldwide live with dementia, a number that's expected to rise as the global population ages.

7 Dec 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Common viruses may play a role in some cases of Alzheimer's disease

Researchers from Oxford's Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer's disease (AD).

3 Aug 2022

New disease-modifying therapy for Alzheimer's disease may involve whole blood exchange

A novel, disease-modifying therapy for Alzheimer's disease may involve the whole exchange of blood, which effectively decreased the formation of amyloid plaque in the brains of mice, according to a new study from UTHealth Houston.

15 Jul 2022

Portable biosensor device for early detection of chronic kidney disease

A new method for early detection of chronic kidney disease, which affects an estimated 7% of the world’s population, has been shown to have potential to service rural and remote patients and communities with limited medical services.

1 Jul 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

Exercise maintains insulin and body mass index levels to help protect brain volume

Studies have shown that exercise helps protect brain cells. A new study looking at the mechanisms involved in this relationship suggests that the role exercise plays in maintaining insulin and body mass index levels may help protect brain volume and thus help stave off dementia.

14 Apr 2022

Beta-amyloid deposits found in young patients with COVID-19

A new study describes the finding that patients of COVID-19 exhibit large amounts of focal β-amyloid deposits in their neocortical tissues.

25 Jan 2022

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

UT Southwestern study suggests potential way to prevent Alzheimer’s disease

A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer's disease.

29 Oct 2021

Early accumulation of tau proteins in the brain more effective at predicting memory impairment

Researchers at Karolinska Institutet in Sweden have compared how well different Alzheimer's biomarkers predict the progression of the disease and its effect on memory.

1 Oct 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Facing headwinds on new Alzheimer’s drug, Biogen launches controversial campaign

Do you sometimes lose your train of thought or feel a bit more anxious than is typical for you?

23 Jul 2021

Promising preclinical results of new dementia treatment candidate set the stage for human trials

Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.

29 Jun 2021