Anaphylaxis News and Research

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Anaphylaxis is an acute multi-system severe type I hypersensitivity reaction. Due in part to the variety of definitions, between 1% and 15% of the population of the United States can be considered "at risk" for having an anaphylactic reaction if they are exposed to one or more allergens. Of those people who actually experience anaphylaxis, up to 1% may die as a result.

Antibiotics ineffective for cough treatment in lower respiratory tract infections

Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment in U.S. primary or urgent care settings for lower-respiratory tract infections.

15 Apr 2024

New study finds interferon-γ release assays more effective than skin tests in predicting tuberculosis

The performance of tuberculin skin test (TST) and interferon-γ release assays (IGRAs) in predicting tuberculosis (TB).

5 Apr 2024

Milk ladder approach offers hope for children with cow's milk allergy

Researchers review milk ladder use for managing cow's milk allergy in children, emphasizing its potential in safely introducing cow's milk to induce tolerance and the need for standardization and further research.

19 Mar 2024

FDA approves omalizumab for food allergy reactions based on NIH research

Today's Food and Drug Administration approval of a supplemental biologics license for the monoclonal antibody omalizumab (Xolair) highlights the vital role of the National Institutes of Health-supported research that underpins the FDA decision.

16 Feb 2024

New insights on how diet regulates allergic responses

The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life.

1 Feb 2024

Nutrigenomics paves the way for customized diets in lactose intolerance care

The current evidence on omics tools that allow for developing tailored nutrition strategies for individuals with lactose intolerance (LI).

24 Jan 2024

What is the association between prenatal opioid exposure and risk of immune-related conditions?

Researchers compared the risk of hospitalization and emergency department presentation for immune-related conditions in children with and without prenatal opioid exposure.

19 Jan 2024

Breakthrough nano-shield blocks selective allergic reactions

Northwestern University researchers have developed the first selective therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.

16 Jan 2024

Two new practice parameters offer recommendations for treating anaphylaxis and atopic dermatitis

Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients.

18 Dec 2023

Advancements in food allergy research promise improved diagnosis and treatment options

A review in the Journal of Allergy and Clinical Immunology discusses the global trends in food allergy prevalence, with stabilization in developed regions and an increase in developing countries, alongside advancements in understanding the mechanisms, diagnosis, and treatment of food allergies.

13 Dec 2023

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results of the Phase II SUMMIT trial reported by researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

New method could enhance the ability to detect and predict anaphylaxis during oral food challenges

Food allergies can quickly turn a casual meal into a life-threatening situation.

7 Nov 2023

Balancing act: Navigating elimination diets in allergic kids without compromising nutrition

Recent research underscores the importance of careful management of elimination diets in children with food allergies, ensuring nutritional balance and support for growth. The study advocates for a multidisciplinary approach to help children avoid allergens without compromising their overall health and development.

2 Nov 2023

New survey uncovers lack of awareness about the proper use of adrenaline pens

New research reveals the significant impact severe allergies have on people’s daily lives and mental wellbeing, as well as uncovering an evident lack of awareness about the proper use of adrenaline pens.

14 Oct 2023

Self‐administration of investigational intranasal spray may be a new option to treat rapid heartbeat

A fast-acting medication delivered as a nasal spray may someday allow patients with intermittent rapid heartbeats to treat it themselves as soon as they develop symptoms, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

27 Sep 2023

Could a genetic biomarker predict your risk for severe food allergies?

Researchers at Ann & Robert H. Lurie Children's Hospital of Chicago have identified a genetic biomarker, α-tryptase, that may predict the severity of food allergy reactions. This discovery opens the door for new treatment strategies and offers a way to distinguish patients at risk for severe reactions.

21 Sep 2023

Using ChatGPT to address vaccine hesitancy: a promising tool for guiding users to scientific information?

Researchers assessed ChatGPT's ability to address the 50 most common misconceptions about vaccine safety.

6 Sep 2023

Novavax's protein-based COVID vaccine induces broad functional immune response against XBB subvariants, data shows

Novavax, Inc., a global company advancing protein-based vaccines with its novel Matrix-M™ adjuvant, today announced that its updated protein-based XBB COVID vaccine candidate induced neutralizing antibody responses to the EG.5.1 and XBB.1.16.6 subvariants in small animal and non-human primate studies.

25 Aug 2023

Early life food allergy associated with increased risk of asthma and reduced lung growth

Having a food allergy as a baby is linked to asthma and reduced lung function later in childhood, according to a world first study.

25 Jul 2023