Animal Model News and Research

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Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

Silk from silkworms and spiders may be a promising material for repairing severed nerves

The treatment of nerve injuries with the aid of nerve guidance conduits has led to the desired regenerative success in some, but by no means all, cases.

3 Apr 2023

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

Researchers assessed the impact of BCG vaccination on the protection provided by SARS-CoV-2 vaccination.

28 Mar 2023

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

A review published in the Antioxidants journal aimed to understand the impact of gut microbiota on brain aging.

28 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white matter.

27 Mar 2023

Molecular mechanism involved in the development of type 2 diabetes discovered

Type 2 diabetes is a chronic disease in which the body does not produce enough insulin, or does not use it efficiently.

23 Mar 2023

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

In a recent study published in the npj vaccines journal, researchers assessed the immune protection elicited by messenger ribonucleic acid (mRNA) vaccines delivering Hepatitis C virus (HCV) E1 and modified E2.

23 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2.

22 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Researchers find new way to remove waste after brain hemorrhage

University of Helsinki and Taiwanese researchers have found a new way to remove waste from the brain after hemorrhage.

17 Mar 2023

Which exercises might reduce pro-inflammatory and enhance anti-inflammatory cytokines in older people with mild cognitive impairment or Alzheimer's disease?

Researchers investigated which exercises might enhance anti-inflammatory cytokines and reduce pro-inflammatory cytokines in patients with dementia or mild cognitive impairment.

17 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Animal Model News and Research

Study explains why leukemia survivors experience negative effects on blood formation decades later

Silk from silkworms and spiders may be a promising material for repairing severed nerves

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

New study suggests broad neutralizing antibody could provide three years of COVID protection

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

Molecular mechanism involved in the development of type 2 diabetes discovered

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Researchers find new way to remove waste after brain hemorrhage

Which exercises might reduce pro-inflammatory and enhance anti-inflammatory cytokines in older people with mild cognitive impairment or Alzheimer's disease?

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Lassa virus vaccine induces rapid protection in an animal model

New genetic animal model may inform potential therapeutic options for Down syndrome

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

New technique helps surgeons reconstruct more natural-looking nipples after mastectomy

Mutant mice models created for studying bipolar disorder

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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