Anti Epileptic Drug News and Research

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'Bioequivalence' shown for generic lamotrigine

The EQUIGEN trial shows that switching to and between generic versions of lamotrigine does not affect the plasma levels achieved by patients with epilepsy.

17 Feb 2016

Study confirms no detectable difference when switching between generics

While approved generics are required to be equivalent to their brand-named counterparts in terms of active ingredients, some may wonder if a switch between generics could cause problems for someone who relies on daily medication to control a severe, chronic condition, like seizures.

12 Feb 2016

BetterYou's revolutionary daily oral vitamin spray could boost vitamin D levels in children with epilepsy

A revolutionary daily oral vitamin spray by health pioneers BetterYou can boost vitamin D levels in deficient children, particularly common in those with epilepsy.

From BetterYou Ltd 8 Feb 2016

Neuroprotection powers for phenytoin in acute optic neuritis

Selective sodium channel blockade with the anti-epileptic drug phenytoin protects against acute demyelinating optic neuritis, researchers report.

29 Jan 2016

Early promise for cannabis extract treatment in epilepsy

A preliminary, open-label study suggests that cannabidiol may be a useful adjunctive treatment in adults and children with intractable epilepsy.

7 Jan 2016

Purified cannabinoid reduces seizures in children and young adults with treatment-resistant epilepsy

Children and young adults with severe forms of epilepsy that does not respond to standard antiepileptic drugs have fewer seizures when treated with purified cannabinoid, according to a multi-center study led by researchers from UCSF Benioff Children's Hospital San Francisco.

6 Jan 2016

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

Alexza Pharmaceuticals, Inc. today announced interim results of its Phase 2a study of AZ-002 (Staccato alprazolam) in epilepsy patients. AZ-002 produced a dose-related decrease in mean Standardized Photosensivity Range (SPR), the primary endpoint in the study.

21 Dec 2015

Common mechanism may underlie epilepsy, suicidality

Patients with epilepsy have an increased risk of attempting suicide, which precedes their epilepsy diagnosis, say researchers.

18 Dec 2015

For people with epilepsy, the mental health treatments are not clearly understood

Mental health issues such as depression or anxiety are often neglected or misunderstood in people who also have co-morbidity with epilepsy.

18 Nov 2015

Seizure control improves for TSC patients undergoing more extensive surgery

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

16 Oct 2015

Anteroinferior encephalocele a rare but important epilepsy cause

Clinicians should actively search for anteroinferior encephaloceles in patients with treatment-refractory epilepsy, say researchers.

2 Oct 2015

AgeneBio's HOPE4MCI Phase 3 trial receives support from NIH

AgeneBio, a biopharmaceutical company developing innovative therapeutics for unserved patients battling neurodegeneration, announced today that its HOPE4MCI Phase 3 clinical trial has received support from the National Institutes of Health.

15 Sep 2015

Elite CBD Remedy Tincture now available through Mary's Nutritionals

Elite Botanicals, the leading cultivator of CBD-rich hemp in Colorado, today announced that it's Elite CBD Remedy Tincture is now available through medical and recreational dispensaries in Colorado, as well as online through Mary's Nutritionals.

26 Aug 2015

Antiepileptic monotherapy does not increase intrauterine death risk

Neither type nor dosage of antiepileptic drug affects the risk of intrauterine death among pregnant women with epilepsy when given as monotherapy, suggests research.

4 Aug 2015

Focal symptoms may be prognostic in generalised epilepsies

Symptoms consistent with focal seizures are often reported by patients who have idiopathic generalised epilepsies and are associated with a short duration of freedom from seizures, say researchers.

24 Jul 2015

Neurologists evaluate application of smartphones in epilepsy care

While many people with epilepsy can control their seizures with medication, those unpredictable and involuntary changes in behavior and consciousness can be limiting for others. Neurologists writing in the International Journal of Epilepsy evaluated the application of smartphones in epilepsy care.

1 Jul 2015

Clonazepam study supports European practice in status epilepticus

A study comparing outcomes among patients treated with first-line lorazepam, midazolam or clonazepam for status epilepticus finds that the three drugs are broadly equivalent.

22 Jun 2015

Upsher-Smith announces FDA approval of sNDA for Qudexy XR extended-release capsules

Upsher-Smith Laboratories, Inc. announced that it has received U.S. Food and Drug Administration approval of a supplemental new drug application (sNDA) for Qudexy XR (topiramate) extended-release capsules for use as initial monotherapy in patients two years of age and older who are experiencing partial-onset seizures (POS) or primary generalized tonic-clonic seizures.

2 Jun 2015

New insights on strategies to treat infants with seizures

New recommendations offer insights on strategies for treating infants with seizures. In an Epilepsia report, child neurologists who are members of the International League Against Epilepsy note that intervening at the time of a febrile seizure does not alter the risk for subsequent epilepsy, and there is no evidence to support the use of antiepileptic drugs for simple febrile seizures.

2 Jun 2015