Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Enterosignatures provide an interpretable and generic model that enables an intuitive characterization of gut microbiome composition

Researchers used a diverse set of 5,230 gut metagenomes to train a study model.

21 Jun 2023

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Study removes AMR plasmids using a mobile, broad-host-range CRISPR-Cas9 delivery tool.

21 Jun 2023

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

The 6th World Congress on Targeting Phage Therapy 2023 that was held on June 1-2 in Paris, and gathered more than 150 attendees from 30+ different countries. Targeting Phage Therapy 2023 included more than 71 presentations between major talks, short orals, and posters.

20 Jun 2023

Trends in the prevalence of hospital-associated infections caused by high-priority pathogens

Researchers explored the prevalence of antibiotic-resistant hospital-associated infections worldwide.

19 Jun 2023

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

Bio-TUNE project aims to develop materials with high antibacterial potential and efficient tissue integration

The UPC's Biomaterials, Biomechanics and Tissue Engineering Group (BBT) leads the international project Bio-TUNE, which aims to develop multifunctional materials with high antibacterial potential and efficient tissue integration.

15 Jun 2023

Silver-doped glass fibers used as a potential treatment for wound healing, finds study

Researchers at the University of Birmingham have demonstrated that silver retains antimicrobial activity for longer when it is impregnated into 'bioactive glass', and shown for the first time how this promising combination delivers more long-lasting antimicrobial wound protection than conventional alternatives.

15 Jun 2023

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

14 Jun 2023

Tea tree oil holds promise as a natural remedy for acne

The anti-acne properties of tea tree oil, which is widely known for its antibacterial, anti-inflammatory, and anti-oxidant properties.

14 Jun 2023

Antibiotic targeting Fusobacterium reduces the formation of lesions associated with endometriosis

A research group from the Graduate School of Medicine and iGCORE at Nagoya University in Japan, has discovered that using an antibiotic to target Fusobacterium reduced the formation of lesions associated with endometriosis, a gynecological disorder characterized by endometrial tissue usually found inside the uterus being found outside it.

14 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

13 Jun 2023

Blood culture vs. metagenomic next-generation sequencing for the detection of pathogenic microbes in patients with suspected bloodstream infections

A recent study published in Scientific Reports compared the detection of pathogenic microbes between blood culture and metagenomic next-generation sequencing in patients suspected of bloodstream infections.

13 Jun 2023

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

In a recent article published in the journal PLOS Medicine, researchers performed a prospective, longitudinal study to estimate the proportion of outpatient consultations resulting in inappropriate antibiotic prescriptions in young children in three low- and middle-income countries (LMICs), Madagascar, Senegal, and Cambodia.

13 Jun 2023

Oliver Dowden: New Biothreats Radar will be key to the UK’s fight against future biological threats

A new Biothreats Radar capable of scanning biological risks that pose a threat to the public will be key to the UK's fight and preparation for future pandemics, the Deputy Prime Minister Oliver Dowden has announced today (Monday 12 June).

12 Jun 2023

Interventions based on Choosing Wisely guidelines can reduce antibiotic overuse at safety-net hospitals

A statewide pay-for-performance intervention based on a set of guidelines called Choosing Wisely reduced rates of inappropriate antibiotic prescriptions to treat acute respiratory tract infections by an average of 18 percentage points, from 43% to 25%, across two large Los Angeles safety net hospitals.

12 Jun 2023

Keynote speakers of ELRIG Drug Discovery 2023 announced

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for Drug Discovery 2023, taking place at the ACC in Liverpool from 18–19 October. Prof Janet Hemingway CBE, FRS, Founding Director of Infection Innovation Consortium (iiCON), and Dr Dave Powell, Chief Scientific Officer (CSO) of LifeArc will lead this year’s event focussing on diverse thinking and new perspectives.

10 Jun 2023

Study reveals insights into the relationship between peer comparison and job satisfaction among clinicians

Showing people how their behavior compares to their peers is a commonly used method to improve behavior. But in the wake of a global pandemic that exacerbated health care providers' job dissatisfaction and burnout, questions remain about the potentially negative effects of peer comparison on the well-being of clinicians.

9 Jun 2023

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

Two new studies in Science and Science Immunology spotlight a group of intestinal T cells with α4β7 integrin receptors that could be targeted to prevent resistance to immune checkpoint blockade (ICB) cancer immunotherapy.

8 Jun 2023

Global study provides high-quality data to improve treatment of newborn babies with sepsis

A global observational study, which involved more than 3,200 newborn babies suffering from sepsis in 19 hospitals in 11 countries, has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.

8 Jun 2023

How do antibiotics affect the ecology of the gut microbiome?

Each person's gut microbiome contains a specific community of microorganisms that normally remains stable for years. However, it can be thrown off balance by factors such as dietary changes, infections or medications. Antibiotics in particular have a strong influence on the microbiome. In response, microorganisms employ various resistance mechanisms, with individual bacterial populations evolving through selection of antibiotic-resistant variants. Yet, the extent and mechanisms of these processes and their impact on the ecology of the microbial community are poorly understood.

7 Jun 2023

Antibiotic News and Research

Further Reading

Enterosignatures provide an interpretable and generic model that enables an intuitive characterization of gut microbiome composition

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

Trends in the prevalence of hospital-associated infections caused by high-priority pathogens

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

Bio-TUNE project aims to develop materials with high antibacterial potential and efficient tissue integration

Silver-doped glass fibers used as a potential treatment for wound healing, finds study

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

Tea tree oil holds promise as a natural remedy for acne

Antibiotic targeting Fusobacterium reduces the formation of lesions associated with endometriosis

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Blood culture vs. metagenomic next-generation sequencing for the detection of pathogenic microbes in patients with suspected bloodstream infections

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

Oliver Dowden: New Biothreats Radar will be key to the UK’s fight against future biological threats

Interventions based on Choosing Wisely guidelines can reduce antibiotic overuse at safety-net hospitals

Keynote speakers of ELRIG Drug Discovery 2023 announced

Study reveals insights into the relationship between peer comparison and job satisfaction among clinicians

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

Global study provides high-quality data to improve treatment of newborn babies with sepsis

How do antibiotics affect the ecology of the gut microbiome?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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