Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Antibiotic functioning as an off switch being developed for gene therapy of Parkinson's disease

A common antibiotic can function as an "off switch" for a gene therapy being developed for Parkinson's disease, according to University of Florida researchers writing online in advance of September's Molecular Therapy.

29 Aug 2009

Polymedix And UMass receive Phase I STTR contract for research on drug-resistant bacteria treatments

PolyMedix, Inc. (OTC BB: PYMX, www.polymedix.com), an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders, and the University of Massachusetts, have received a Phase I Small Business Technology Transfer (STTR) contract in the amount of $100,000 to support research to identify lead antimicrobial compounds to effectively treat multi-drug resistant and biofilm-embedded bacteria.

28 Aug 2009

NIMH grants Xhale $1.7 million to develop the SMART medication adherence system for HIV/AIDS therapies

Xhale, Inc. has been awarded a $1.7 million Small Business Innovation Research (SBIR) Phase II grant by the NIH National Institute of Mental Health (NIMH) to continue the development of SMART (Self Monitoring and Reporting Therapeutics), a breath-based medication adherence system for HIV/AIDS therapies.

28 Aug 2009

Mylan Pharmaceuticals markets FDA approved first generic version of Sanofi Aventis' BenzaClin

Mylan Inc. (Nasdaq: MYL) today announced that its subsidiary Mylan Pharmaceuticals Inc. has begun to market 1% Clindamycin and 5% Benzoyl Peroxide Gel based on an agreement with licensing partner Dow Pharmaceutical Sciences, a subsidiary of Valeant Pharmaceuticals International. The preparation is the first generic version of Sanofi Aventis' BenzaClin(R) to be approved by the U.S. Food and Drug Administration (FDA).

27 Aug 2009

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

Lakewood-Amedex Inc., (L-A), the anti-infectives biopharmaceutical company developing a unique portfolio of anti-bacterial and anti-viral products including NuBiotics, a novel family of synthetic anti-bacterial compounds, and anti-viral products against hepatitis, HIV and influenza, announced today that it is accelerating development of its broad spectrum anti-influenza product into clinical studies.

27 Aug 2009

Angiotensin arrests lung tumor growth by inhibiting blood vessel formation

In new animal research done by investigators at Wake Forest University School of Medicine, scientists have discovered a treatment effective in mice at blocking the growth and shrinking the size of lung cancer tumors, one of the leading causes of cancer death in the world.

27 Aug 2009

Hiberix receives accelerated approval from FDA to overcome nationwide shortage

The U.S. Food and Drug Administration today approved Hiberix, a Haemophilus influenzae Type b (Hib) vaccine, as a booster dose for children 15 months through 4 years old. Hiberix is manufactured by GlaxoSmithKline, with U.S. headquarters in Research Triangle Park, N.C. and Philadelphia.

26 Aug 2009

FDA accepts for filing Salix Pharmaceuticals' NDA for rifaximin tablets

Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) today announced the Food and Drug Administration (FDA) has accepted for filing and designated for Priority Review the Company’s New Drug Application (NDA) for rifaximin tablets 550 mg for the maintenance of remission of hepatic encephalopathy (HE). Additionally, the FDA has informed the Company of its plan to schedule an Advisory Committee meeting in late February 2010 to discuss the application.

25 Aug 2009

FDA issues marketing approval for APP Pharmaceuticals' Penicillin G potassium for Injection, USP

APP Pharmaceuticals, Inc., a wholly owned subsidiary of Fresenius Kabi Pharmaceuticals Holding, Inc. (NASDAQ: APCVZ), announced today that it has received approval from the U.S. Food and Drug Administration (FDA) to market penicillin G potassium for Injection, USP, in two dosage strengths. Penicillin G is therapeutically equivalent to the reference drug PfizerPen™ G, which is marketed by the innovator Pfizer, Inc.

25 Aug 2009

Washington post examines spread of drug-resistant TB in Russia

The Washington Post examines the spread of drug-resistant tuberculosis in Russia where "[p]reliminary surveys have recorded an uptick in infections," which could be the "start of a surge fueled by declining living standards and deteriorating medical care resulting from the country's worst economic slowdown in a decade," experts say.

24 Aug 2009

NovaBay Pharmaceuticals to deliver two poster presentations describing results from new studies of NVC-422

NovaBay(R) Pharmaceuticals, Inc., a clinical stage company developing non-antibiotic anti-infective compounds for the treatment or prevention of a wide range of bacterial, viral, and fungal infections, will deliver two poster presentations at the 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, CA.

24 Aug 2009

Researchers discover elusive nanoscale movements of ribosomes at work

Researchers at the University of California, Berkeley, have for the first time captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions and amino acids to churn out proteins.

24 Aug 2009

Innovotech reports year-on-year revenue increase for second-quarter 2009

Innovotech Inc. (TSX VENTURE:IOT) today announced its unaudited financial and operational results for the three and six month periods ended June 30, 2009.

21 Aug 2009

MicroPhage's new platform for rapid identification of bacterial infections

MicroPhage announced today the launch of its multi-site clinical trial to support a U.S. Food and Drug Administration (FDA) premarket notification [510(k)]. The platform has been developed to rapidly identify bacterial infections and determine antibiotic susceptibility or resistance to aid physicians in antibiotic management.

21 Aug 2009

Research study discovers lethal effects of tetracycline and chloramphenicol against certain bacterial strains

By studying the intricate mechanisms at work in protein production, a Princeton-led team has discovered why certain kinds of antibiotics are so effective. In doing so, they also have discovered how one protein protects against cell death, shedding light on a natural cancer-fighting process.

21 Aug 2009

New findings to prevent urinary tract infections

Researchers at Duke University Medical Center may have a new way to stop and even prevent the urinary tract infections (UTIs) that plague more than a third of all adults, some of them repeatedly.

21 Aug 2009

New study reveals that influenza vaccination may prevent inappropriate antibiotic use

We all know that influenza vaccination helps prevent disease, but a new study from Canada suggests it may also prevent another public health problem: inappropriate antibiotic use. The findings come from a new study in the September 1, 2009 issue of Clinical Infectious Disease, which is now available online.

21 Aug 2009

DNA-encased carbon nanotubes used for treating human prostate cancer tumors in mice

Researchers at Wake Forest University School of Medicine have destroyed prostate cancer tumors in mice by injecting them with specially-coated, miniscule carbon tubes and then superheating the tubes with a brief zap of a laser.

20 Aug 2009

Discovery of compounds that selectively kills cancer stem cells

The cancer stem cells that drive tumor growth and resist chemotherapies and radiation treatments that kill other cancer cells aren't invincible after all. Researchers reporting online on August 13th in the journal Cell, a Cell Press publication, have discovered the first compound that targets those cancer stem cells directly.

13 Aug 2009

Forest Labs and Astrazeneca to co-develop and commercialize ceftaroline

Forest Laboratories (NYSE:FRX) and AstraZeneca (NYSE:AZN) announced today they have entered into a definitive collaboration agreement to co-develop and commercialize ceftaroline in all markets outside the United States, Canada and Japan.

12 Aug 2009

Antibiotic News and Research

Further Reading

Antibiotic functioning as an off switch being developed for gene therapy of Parkinson's disease

Polymedix And UMass receive Phase I STTR contract for research on drug-resistant bacteria treatments

NIMH grants Xhale $1.7 million to develop the SMART medication adherence system for HIV/AIDS therapies

Mylan Pharmaceuticals markets FDA approved first generic version of Sanofi Aventis' BenzaClin

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

Angiotensin arrests lung tumor growth by inhibiting blood vessel formation

Hiberix receives accelerated approval from FDA to overcome nationwide shortage

FDA accepts for filing Salix Pharmaceuticals' NDA for rifaximin tablets

FDA issues marketing approval for APP Pharmaceuticals' Penicillin G potassium for Injection, USP

Washington post examines spread of drug-resistant TB in Russia

NovaBay Pharmaceuticals to deliver two poster presentations describing results from new studies of NVC-422

Researchers discover elusive nanoscale movements of ribosomes at work

Innovotech reports year-on-year revenue increase for second-quarter 2009

MicroPhage's new platform for rapid identification of bacterial infections

Research study discovers lethal effects of tetracycline and chloramphenicol against certain bacterial strains

New findings to prevent urinary tract infections

New study reveals that influenza vaccination may prevent inappropriate antibiotic use

DNA-encased carbon nanotubes used for treating human prostate cancer tumors in mice

Discovery of compounds that selectively kills cancer stem cells

Forest Labs and Astrazeneca to co-develop and commercialize ceftaroline

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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