Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Jumping genes help explain immune system's remarkable ability

A team led by Johns Hopkins scientists has found the first clear evidence that the process behind the human immune system's remarkable ability to recognize and respond to a million different proteins might have originated from a family of genes whose only apparent function is to jump around in genetic material.

22 Dec 2004

Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

20 new policies adopted by American Public Health Association

The American Public Health Association recently adopted 20 policies addressing a broad range of issues in public health from underage alcohol consumption and nutrition labeling in restaurants to the supply of flu vaccinations and threats to immigrants’ health care.

21 Dec 2004

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Benzoyl peroxide effective treatment for acne

Results of a UK study in this week’s issue of THE LANCET highlight how over the counter benzoyl peroxide (BEN-zoe-ill per-OX-ide) lotion is as good as prescription antibiotics for the treatment of mild to moderate facial acne.

20 Dec 2004

Permanent resistance to antibiotics cannot be prevented

Dutch research has shown that the development of permanent resistance by bacteria and fungi against antibiotics cannot be prevented in the longer-term. The only solution is to reduce the dependence on antibiotics by using these less.

20 Dec 2004

Study models impact of anthrax vaccine

Rapidly distributing antibiotics to people exposed to anthrax spores during a bioterrorist attack, could by itself, prevent about 70 percent of anthrax infections from occurring, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

16 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Link found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw

Doctors at Long Island Jewish (LIJ) Medical Center recently discovered a link between a common chemotherapy drug and a serious bone disease called osteonecrosis of the jaw (ONJ).

13 Dec 2004

Diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems

Diabetes affects 18.2 million people in the United States and is expected to double by the year 2010. Additionally, diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems than non-diabetics

13 Dec 2004

Findings could lead to new knowledge that could speed the development of drugs to block botulism or tetanus toxins more rapidly

The first detailed structure of a botulism toxin attached to its target protein reveals that the toxin snakes the protein around itself — a sort of “reverse anaconda” — to recognize the receptor.

13 Dec 2004

Molecular Achilles heel in the organism that causes pneumonia

Scientists have found a “molecular Achilles heel” in the organism that causes pneumonia, providing a target for the development of a new class of antibiotics that could eventually eradicate the disease.

13 Dec 2004

Study sheds light on how bacteria persist despite antibiotics

Researchers at the Hebrew University of Jerusalem and Rockefeller University in New York have demonstrated the constant presence of antibiotic-tolerant "persistent cells" within bacteria colonies and have shown, through mathematical modeling, how these cells develop into "normal" cells following their survival of even heavy dosages of antibiotics.

13 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

New research aims to reduce deaths and ease burden on hospitals

New research by scientists at Australia's Macquarie University will investigate antibiotic resistance genes in humans in an effort to combat worldwide death rates due to infectious diseases and reduce the growing burden on our health system by decreasing patients' length of stay.

6 Dec 2004

New and revealing portrait of Yersinia pestis emerges

Yersinia pestis, the causative agent of the “Black Death” or “Bubonic” plague, has been a scourge of human civilization. One of the most virulent bacterial pathogens known, killing nearly 90% of those infected, Y. pestis was responsible for three historic pandemics that shattered whole societies.

4 Dec 2004

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

People could be exposed to antibiotic-resistant bacteria from breathing the air from concentrated swine feeding facilities, according to researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Dec 2004

FDA approval of cream to treat bacterial vaginosis

KV Pharmaceutical Company has announced that it has received approval from the United States Food and Drug Administration (FDA) to market Clindesse (clindamycin phosphate) Vaginal Cream, 2%, a single-dose prescription cream therapy indicated to treat bacterial vaginosis ("BV").

3 Dec 2004

Nanoscale switch could serve as sensor, medical tool

Improving significantly on an early prototype, Johns Hopkins University researchers have found a new way to join two unrelated proteins to create a molecular switch, a nanoscale "device" in which one biochemical partner controls the activity of the other.

29 Nov 2004

Rifampicin can prevent the formation of protein fibrils associated with Parkinson's disease

Researchers at the University of California, Santa Cruz, have shown that rifampicin, an antibiotic used to treat leprosy and tuberculosis, can prevent the formation of protein fibrils associated with the death of brain cells in people with Parkinson's disease. The drug also dissolved existing fibrils in laboratory tests.

29 Nov 2004

Antibiotic News and Research

Further Reading

Jumping genes help explain immune system's remarkable ability

Study finds new method can improve chemo survival

20 new policies adopted by American Public Health Association

Study on first new potential drug for tuberculosis in 40 years

Benzoyl peroxide effective treatment for acne

Permanent resistance to antibiotics cannot be prevented

Study models impact of anthrax vaccine

Scientists have identified a novel anti-tuberculosis (TB) compound

Link found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw

Diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems

Findings could lead to new knowledge that could speed the development of drugs to block botulism or tetanus toxins more rapidly

Molecular Achilles heel in the organism that causes pneumonia

Study sheds light on how bacteria persist despite antibiotics

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

New research aims to reduce deaths and ease burden on hospitals

New and revealing portrait of Yersinia pestis emerges

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

FDA approval of cream to treat bacterial vaginosis

Nanoscale switch could serve as sensor, medical tool

Rifampicin can prevent the formation of protein fibrils associated with Parkinson's disease

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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