Antibiotic Resistance News and Research

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Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

Fungicide resistance: A global threat to human, animal, and plant health

Fungi can cause disease in both humans, animals, and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production.

9 Feb 2024

Reducing unnecessary testing or treatments in older patients

When a doctor ordered a routine prostate screening for an 80-year-old man -; as doctors often do -; a dramatic yellow alert popped up on the electronic health record with dire warnings.

7 Feb 2024

Cirrhosis patients face mixed infection outcomes amid pandemic healthcare shifts

The COVID-19 pandemic's influence on healthcare systems led to mixed outcomes for patients with cirrhosis, showing stable infection rates but a rise in multi-drug resistant organism (MDRO) infections.

7 Feb 2024

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections.

7 Feb 2024

Machine learning can help predict the risk of bacterial co-infections in hospitalized COVID-19 patients

University of Queensland researchers have used machine learning to help predict the risk of secondary bacterial infections in hospitalized COVID-19 patients.

2 Feb 2024

Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

Study shows that a single dose of typhoid conjugate vaccine provides over four years of protection against typhoid fever in Malawian children, proving effective across all age groups.

31 Jan 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes COVID-19, binds to on the surface of human cells.

22 Jan 2024

Bacteria's "suicidal" immune system boosts antibiotic power against cholera

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

19 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

International research collaboration leads to breakthrough in antibiotic resistance testing using DNA sequencing

The accuracy of antibiotic resistance determination from Enterococcus faecium genomes for diagnostic purposes.

15 Jan 2024

Researchers uncover role of persister cells in antibiotic resistance

Antibiotic overuse can lead to antibiotic resistance, but classic antibiotic resistance might not completely explain why antibiotics sometimes fail.

12 Jan 2024

Superbug spread is not just about antibiotics, new study shows

For the first time, researchers have analyzed the impact of antibiotic use on the rise of treatment-resistant bacteria over the last 20 years in the UK and Norway. They show that while the increase in drug use has amplified the spread of superbugs, it is not the only driver.

11 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

Antibiotic Resistance News and Research

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Fungicide resistance: A global threat to human, animal, and plant health

Reducing unnecessary testing or treatments in older patients

Cirrhosis patients face mixed infection outcomes amid pandemic healthcare shifts

Researchers identify a new approach to controlling bacterial infections

Machine learning can help predict the risk of bacterial co-infections in hospitalized COVID-19 patients

Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells

Bacteria's "suicidal" immune system boosts antibiotic power against cholera

Understanding antimicrobial resistance in hospital-acquired pneumonia

New study shows how brain glucose affects fungal disease treatment

International research collaboration leads to breakthrough in antibiotic resistance testing using DNA sequencing

Researchers uncover role of persister cells in antibiotic resistance

Superbug spread is not just about antibiotics, new study shows

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

New family of polymers can kill bacteria without inducing antibiotic resistance

First new antibiotic class in decades discovered using explainable AI platform

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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