Antibiotic Resistance News and Research

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Forest Labs and Astrazeneca to co-develop and commercialize ceftaroline

Forest Laboratories (NYSE:FRX) and AstraZeneca (NYSE:AZN) announced today they have entered into a definitive collaboration agreement to co-develop and commercialize ceftaroline in all markets outside the United States, Canada and Japan.

12 Aug 2009

Antibiotic prescribing should be standardized across Europe to help tackle resistance

Antibiotic prescribing for respiratory illnesses should be standardised across Europe to help reduce inappropriate prescribing and resistance, say experts in a study published on bmj.com.

24 Jun 2009

Preventing spread of infectious diseases is everyone’s responsibility – and everyone’s job

According to a report published today, we must all share responsibility for preventing the spread of diseases such as swine flu, SARS, avian influenza, diarrhoeal and skin diseases, and even the common cold.

16 Jun 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

Dangerous liaisons: bacterial 'sex' causes antibiotic resistance

Some disease-causing bacteria are becoming resistant to antibiotics because they have peculiar sex lives, say researchers publishing new results today in the journal Science.

12 Jun 2009

Research looks at ways to reduce the over-prescribing of antibiotics

Improving communications skills and the use of a simple blood test could help cut the growing number of inappropriate prescriptions of antibiotics, a joint Cardiff University trial has discovered.

22 May 2009

Aerosol delivery of antibiotics via nanoparticles

Aerosol delivery of antibiotics via nanoparticles may provide a means to improve drug delivery and increase patient compliance, thus reducing the severity of individual illnesses, the spread of epidemics, and possibly even retarding antibiotic resistance.

19 May 2009

Bacteria create aquatic superbugs in waste treatment plants

For bacteria in wastewater treatment plants, the stars align perfectly to create a hedonistic mating ground for antibiotic-resistant superbugs eventually discharged into streams and lakes.

13 May 2009

New, more effective nisin antibiotics combat superbugs and food diseases

Researchers at University College Cork have used bioengineering to produce a new generation of natural antibiotics that target harmful micro-organisms such as MRSA and the food-borne pathogen, Listeria monocytogenes

30 Mar 2009

Slow-growing tuberculosis bacteria point the way to new drug development

The discovery of a large number of slow-growing Mycobacterium tuberculosis bacteria, which cause tuberculosis (TB), in the lungs of TB patients could be an important step forward in the design of new anti-TB drugs.

30 Mar 2009

FDA approves new indication for Wyeth's Tygacil (tigecycline)

Wyeth Pharmaceuticals, a division of Wyeth has announced that the U.S. Food and Drug Administration (FDA) approved Tygacil (tigecycline), for the treatment of adult patients with community-acquired bacterial pneumonia (CABP) caused by susceptible strains of indicated pathogens.

24 Mar 2009

Drug combo shows potential for treating extensively drug resistant tuberculosis

A combination of two FDA-approved drugs, already approved for fighting other bacterial infections, shows potential for treating extensively drug resistant tuberculosis (XDR-TB), the most deadly form of the infection.

26 Feb 2009

Antimicrobial resistance in clinics, hospitals and at home

Antibiotic resistance and the rise of illnesses that cannot be treated easily because of drug resistance is a health concern around the world.

16 Feb 2009

Super-fine oil-and-water emulsion protects against superbugs that kill cystic fibrosis patients

University of Michigan scientists report highly encouraging evidence that a super-fine oil-and-water emulsion, already shown to kill many other microbes, may be able to quell the ravaging, often drug-resistant infections that cause nearly all cystic fibrosis deaths.

5 Feb 2009

Quinolone-resistant gonorrhea increases in Ontario

The prevalence of quinolone-resistant gonorrhea has increased rapidly in Ontario - Canada's most populous province - from a rate of 2% in 2001 to 28% in 2006, found a study published in CMAJ.

2 Feb 2009

MRSA head and neck infections increase among children

Rates of antibiotic-resistant head and neck infections increased in pediatric patients nationwide between 2001 and 2006, according to a report in the January issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

19 Jan 2009

Thumbs down by experts on plans to make certain meds OTC

Government plans to make certain prescription-only drugs for common problems available over the counter have overwhelmingly been given the thumbs down by healthcare professionals, reveals a survey of readers of the influential Drug and Therapeutics Bulletin ( DTB ).

13 Jan 2009

Tuberculosis commandeers body's defenses to gain foothold

Tuberculosis bacteria can commandeer the body's defenses in the early stages of infection and redirect them for their own offensive strategies, according to results reported in the scientific journal, Cell.

9 Jan 2009

Discovery of novel ways to halt the spread of antibiotic resistance

Scientists have identified the structure of a key component of the bacteria behind such diseases as whooping cough, peptic stomach ulcers and Legionnaires' disease.

9 Jan 2009

Discovery of new way for bacteria to transfer toxic genes to unrelated bacterial species

In a laboratory experiment, the scientists from NYU School of Medicine discovered that Staphylococcus aureus, a notorious bacterium that causes toxic shock syndrome and many other types of infections and is the scourge of hospitals nationwide due to its growing antibiotic resistance, could co-opt viral parasites as secret pipelines for transferring toxin genes to vastly different bacterial species.

6 Jan 2009