Antibodies News and Research

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Alternative model addresses the shortcomings of neutrophil-depletion model

s the COVID-19 pandemic continues to spread, researchers are turning their attention to the virus' biology, mechanism of action, and possible treatments. One of the targets are a group of immune cells called "neutrophils", which have been reported to infiltrate the respiratory tract of patients who have died from COVID-19.

2 Jun 2020

New project investigating role of B cells in cardiovascular disease receives $6.5 million grant

Christoph Binder, Professor of Atherosclerosis Research at MedUni Vienna, is to coordinate an international research network investigating the role of B cells in cardiovascular disease.

2 Jun 2020

At-home finger prick COVID-19 antibody testing

The best way to estimate the actual prevalence of COVID-19 in the population is by antibody testing. A new study by scientists at Enable Biosciences and published on the preprint server medRxiv* in May 2020 reports the development of fast and sensitive antibody testing kits designed for at-home use. This could significantly boost the measurement of population prevalence of this infection and help understand whether it confers immunity to reinfection.

2 Jun 2020

SARS-CoV-2 started spreading in the United States in January, CDC says

The United States has reported the highest number of infections across the globe, with more than 1.81 million confirmed cases and at least 105,000 deaths. The magnitude of the novel coronavirus spread hints that the virus may have started earlier than previously thought.

2 Jun 2020

New detection platform for rapid diagnosis of infectious diseases

The prompt, precise, and massive detection of a virus is the key to combat infectious diseases such as Covid-19.

1 Jun 2020

Study maps novel coronavirus infection in cells of nasal cavity, airway and lungs

In a major scientific study published in the journal Cell, scientists at the UNC School of Medicine and the UNC Gillings School of Global Public Health have characterized the specific ways in which SARS-CoV-2 – the coronavirus that causes COVID-19 – infects the nasal cavity to a great degree – replicating specific cell types – and infects and replicates progressively less well in cells lower down the respiratory tract, including the lungs.

1 Jun 2020

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

A research group from the University of Texas in Austin described a high-yield production of a stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) that may accelerate the development of vaccines and diagnostic tests. This methodological 'tour de force' paper is currently available on the bioRxiv* preprint server.

1 Jun 2020

Reducing inflammation improves stroke recovery, may extend window for therapy

Reperfusion therapy, the gold standard for stroke treatment, helps restore blood flow after a stroke caused by a clot, preventing loss of brain tissue. However, only about 10% of stroke patients qualify, in part because of reperfusion therapy's narrow treatment window.

1 Jun 2020

SARS-CoV-2 prevalence varies widely across Brazil

Researchers have shown that the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Brazil varies significantly by city and region, with the highest prevalence observed in the North of the country and the lowest seen in South and Center-West regions.

1 Jun 2020

NAU scientist collaborating on vault-based vaccine to prevent and treat COVID-19

C. Todd French, assistant professor of biology and leader of Northern Arizona University's new COVID-19 Testing Service Center, is working with scientists at Vault Pharma, an emerging biotechnology company, to test candidate vaccines against the novel coronavirus.

1 Jun 2020

Significant number of COVID-19 positive cases asymptomatic, raising transmission concerns

There have been many instances of people testing positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who have no symptoms of the infection whatsoever. These asymptomatic patients are, however, still capable of spreading the infection without being aware of it, say experts.

31 May 2020

New review analyzes appropriateness of off-pathway cancer care

Clinical oncology pathways are an important tool, helping cancer care providers and their patients to zero in on the most appropriate care plan.

30 May 2020

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

While breakthrough treatments have emerged for several cancers over the last two decades, driving striking improvements in survival and other clinical outcomes, too little is known about the risk of therapy-related hematologic cancers following targeted and immunotherapeutic approaches.

29 May 2020

Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.

29 May 2020

Researchers review all clinical and research findings related to COVID-19

Due to the devastating worldwide impact of COVID-19, the illness caused by the SARS-CoV-2 virus, there has been unprecedented efforts by clinicians and researchers from around the world to quickly develop safe and effective treatments and vaccines.

29 May 2020

Study shows how toxic protein leads to neuronal death and dementia

Toxic versions of the protein tau are believed to cause the death of neurons of the brain in Alzheimer's disease.

29 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

28 May 2020

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

Aspen was an early COVID-19 hot spot in Colorado, with a cluster of cases in March linked to tourists visiting for its world-famous skiing. Tests were in short supply, making it difficult to know how the virus was spreading.

28 May 2020

SignalChem Biotech Inc. launches COVID-19 elisa kits for diagnostic research

SignalChem, a global leader in cell signaling and protein engineering, has been conducting research on new coronaviruses since the outbreak of the virus.

From SignalChem Biotech Inc. 28 May 2020

Antibodies News and Research

Alternative model addresses the shortcomings of neutrophil-depletion model

New project investigating role of B cells in cardiovascular disease receives $6.5 million grant

At-home finger prick COVID-19 antibody testing

SARS-CoV-2 started spreading in the United States in January, CDC says

New detection platform for rapid diagnosis of infectious diseases

Study maps novel coronavirus infection in cells of nasal cavity, airway and lungs

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

Reducing inflammation improves stroke recovery, may extend window for therapy

SARS-CoV-2 prevalence varies widely across Brazil

NAU scientist collaborating on vault-based vaccine to prevent and treat COVID-19

Significant number of COVID-19 positive cases asymptomatic, raising transmission concerns

New review analyzes appropriateness of off-pathway cancer care

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

Researchers review all clinical and research findings related to COVID-19

Study shows how toxic protein leads to neuronal death and dementia

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

SignalChem Biotech Inc. launches COVID-19 elisa kits for diagnostic research

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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