Anticoagulant News and Research

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Pocket guidelines for assessment and management of cardiovascular risk

A new book of pocket-charts that will help health workers to identify people at risk of heart attacks and strokes and save lives by prescribing the most appropriate treatment is published today by the World Health Organization (WHO). The charts can be adapted for use in any setting, in any country, with any patient.

12 Sep 2007

Improved dosing formula for warfarin (Coumadin)

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients.

5 Sep 2007

Genetic-based dosing in orthopedic patients beginning warfarin therapy

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients. But now the process can be faster and safer, thanks to research conducted at Washington University School of Medicine in St. Louis.

3 Sep 2007

Genetics determine optimal drug dose of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood , the journal of the American Society of Hematology.

22 Aug 2007

Genetic testing can be used to help personalize the therapeutic dosage of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology.

21 Aug 2007

Warfarin more effective than aspirin in prevention of stroke in people with atrial fibrillation

Warfarin is more effective than aspirin in prevention of stroke in people with a certain type of irregular heartbeat who are aged 75 or over, conclude authors of an Article published in this week's edition of The Lancet.

13 Aug 2007

Warfarin versus aspirin for stroke prevention

A study tracking nearly 1,000 over-75s at high risk of stroke has found that the anticoagulant drug warfarin cuts the risk by half in this older population without causing more side-effects than alternatives.

13 Aug 2007

Implantable artificial lung

The University of Michigan Medical School laboratory working to develop an implantable artificial lung that can serve as a bridge to lung transplantation is entering the home stretch.

6 Aug 2007

Studies assess blood clot prevalence outside hospital prevention in hospital

More cases of venous thromboembolism are diagnosed in the three months following hospitalization than during hospitalization, but less than half of inpatients receive medications to prevent blood clots from occurring, according to a report in the July 23 issue of Archives of Internal Medicine.

24 Jul 2007

Computers pass dosage test for thrombosis drugs

The largest ever study into the administration of blood thinning drugs like Warfarin has concluded that dosages calculated by computer are at least as safe and reliable as those provided by trained medical professionals.

From The University of Manchester 20 Jul 2007

Stroke in nonvascular atrial fibrillation

People with atrial fibrillation (AF) have irregular heart beats and have a tendency to form blood clots in the upper chambers (atria) of their hearts.

18 Jul 2007

University Jaume I patents fluorescent sensor

The University Jaume I (UJI) has patented a new fluorescent chemical sensor that is capable of detecting citric acid at low concentrations more rapidly and cheaply than the current optical sensors.

9 Jul 2007

Patients hospitalized with pneumonia at increased risk of major heart problems

A new study suggests patients hospitalized with pneumonia may be at serious risk of new or worsening heart problems.

19 Jun 2007

Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen

A detailed comparison of different types of ceramic nanoparticles has found that those made of silica can efficiently transport therapeutic genes to the spleen and trigger a potent immune response capable of attacking tumors.

14 Jun 2007

Blood-thinning drugs need closer monitoring

Natalie Oake and colleagues report on a meta-analysis of studies that recorded hemorrhages and thromboembolic (blood clot) events in patients taking blood-thinners.

22 May 2007

Drug brand name can influence treatment decisions by patients

The brand name of a drug can strongly influence treatment decisions by patients, according to a randomized trial of decision aids by researchers from McMaster University.

22 May 2007

FDA approves new indication for FRAGMIN for the extended treatment of symptomatic venous thromboembolism

The U.S. Food and Drug Administration (FDA) has approved a new indication for FRAGMIN (dalteparin sodium injection), for the extended treatment of symptomatic venous thromboembolism (VTE) to reduce the recurrence of VTE in patients with cancer.

4 May 2007

Thrombogenics announces agreement with Millipore for commercialization of stem cell technology

ThromboGenics NV has announced that it has completed a global license agreement with Millipore Corporation under which ThromboGenics will exclusively license its technology for production of the proprietary stem cell culture medium marketed by Millipore as RESGRO(x).

17 Apr 2007

Novel anti-oxidant and anti-inflammatory agent reduces coronary events

Heart attacks are caused by a build-up and instability of plaque in the coronary arteries, which is often a result of chronic inflammation of the blood vessel walls.

31 Mar 2007

FDA approves Ceprotin to treat severe congenital protein C deficiency

The U.S. Food and Drug Administration (FDA) today licensed Ceprotin, the first biologic treatment for patients with a rare genetic defect that can cause a potentially life-threatening clotting disorder.

30 Mar 2007