Antidote News and Research

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FDA approves pediatric use of Protopam Chloride

The U.S. Food and Drug Administration has approved the pediatric use of Protopam Chloride (pralidoxime chloride), a drug used to treat poisoning by organophosphate pesticides and chemicals (e.g., nerve agents). The drug is approved to be administered either by intravenous (IV) or intramuscular (IM) injections.

10 Sep 2010

Scientist finds man-made chemical enzyme to neutralize toxin

For the first time ever, a completely man-made chemical enzyme has been successfully used to neutralise a toxin found naturally in fruits and vegetables. While studying for her PhD in chemistry at the University of Copenhagen Dr. Jeannette Bjerre showed how a novel so called chemzyme was able to decompose glycoside esculin, a toxin found in horse-chestnuts.

27 Aug 2010

Unapproved cyanide antidote kits seized from Keystone Pharmaceuticals

At the request of the U.S. Food and Drug Administration, U.S. Marshals today seized $39,000 worth of products labeled as cyanide antidote kits from Keystone Pharmaceuticals in Laguna Hills, California. The seizure warrant was issued by the U.S. District Court for the Central District of California.

23 Jul 2010

US WorldMeds launches Revonto for malignant hyperthermia

US WorldMeds is proud to announce the launch of Revonto™ (dantrolene sodium for injection), the first patented scientific advancement in the treatment of malignant hyperthermia (MH). The time to reconstitute dantrolene sodium for injection has been dramatically reduced to approximately 20 seconds or until the solution is clear. Revonto™ retains the cost-savings of the original dantrolene sodium for injection product while offering a significant improvement in pharmacotherapy.

7 Jul 2010

Training for first responders on antidote for acute cyanide poisoning from fire smoke

Since January 1, 2010 the CPTC has tracked 1,100 civilians treated for smoke inhalation, 413 smoke inhalation deaths, and 125 firefighters who were transported for smoke inhalation treatment. Contrary to popular belief, whether a civilian or a firefighter, smoke inhalation isn't a minor injury - it's deadly.

6 Jul 2010

MHAUS to discuss how medical facilities can best prepare for MH emergency

Preparation is the best plan for Malignant Hyperthermia emergencies, and The Malignant Hyperthermia Association of the United States will be at the Ambulatory Surgery Center Annual Meeting, May 19-22, to answer questions about how medical facilities can best prepare for an MH emergency.

20 May 2010

New Candida treatment more effective than popular remedies

Kathleen Kalaf has been to hell and back in her long fight with systemic Candida. Today, thanks to a new Candida treatment that is more effective than even the most popular Candida remedies, Kalaf is finally free of the yeast overgrowth that stole eight years of her life -- and she wants other Candida sufferers to know about Candida Force (http://www.candidaforce.com).

28 Jan 2010

Attitudes of overweight and normal weight adults regarding exercise at health clubs

Time and time again, it has been documented that regular exercise has many health benefits including lowering risks associated with the comorbidities of obesity.

18 Dec 2009

INS cites FDA-approved Totect antidote for anthracycline extravasations

The third edition of Infusion Nursing: An Evidence-Based Approach, published by the Infusion Nurses Society (INS), includes Totect(®), the only FDA-approved treatment for anthracycline extravasation. Anthracyclines are a group of chemotherapy medications including daunorubicin, doxorubicin, idarubicin and epirubicin that have been used in the treatment of various types of cancer since the early 1970s.

15 Dec 2009

Micromedex 2.0, the new version of clinical information system to be released

Thomson Reuters today announced the release of Micromedex 2.0, the newest version of its market-leading clinical information system.

7 Dec 2009

Public option expected to dominate Senate debate on health reform this week

The Associated Press: "... the all-hands-on-deck Democratic coalition that allowed the bill to advance is fracturing already. ... Some Democratic senators say they'll jump ship from the bill without tighter restrictions on abortion coverage. Others say they'll go unless a government plan to compete with private insurance companies gets tossed overboard.

29 Nov 2009

King Pharmaceuticals receives exclusive rights to market and sell CYANOKIT

King Pharmaceuticals, Inc. announced today that it has licensed from Merck Santé S.A.S., an affiliate of Merck KGaA, Darmstadt, Germany, the exclusive rights to market and sell CYANOKIT® 5 g (hydroxocobalamin for injection) ANTIDOTE in the U.S. CYANOKIT® is indicated for the treatment of known or suspected cyanide poisoning, typically caused by smoke inhalation from fires.

28 Oct 2009

Antidotes effective for treating acute liver failure patients in early stages of disease

The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found.

8 Oct 2009

Researchers engineer antidotes for blood-thinner aptamers

Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately - because the blood thinner and antidote were designed to work together. Researchers at Duke University Medical Center have engineered a way to do this for an entire, versatile class of drugs called aptamers and published their findings in Nature Medicine.

4 Oct 2009

MicroDose initiates Phase 1 clinical trial investigating the pharmacokinetics of atropine inhalation

MicroDose Therapeutx Inc. (formerly MicroDose Technologies) today announced that it has initiated a Phase I study at the University of Pittsburgh Medical Center with atropine sulfate delivered from the MicroDose proprietary dry powder inhaler (DPI). The study is a further step in the development program for an atropine inhaler to treat nerve agent poisoning in military and civil defense applications.

24 Sep 2009

Cyanide toxicity in smoke inhalation victims

"If commercial flying had as many civilian fatalities as those relating to smoke and fire, there would be a public revolt," said Rob Schnepp, CPTC president and assistant chief of special operations for the Alameda County Fire Department in California. "The numbers aren't going down, and this tells me that we aren't addressing the problem adequately.

18 Aug 2009

Akorn reports Q2 2009 financials

Akorn, Inc. (NASDAQ:AKRX) a specialty pharmaceutical company, today reported financial results for the second quarter ended June 30, 2009.

11 Aug 2009

Dodd stretched thin on finance and health roles

Critics are saying that Sen. Chris Dodd, D-Conn., cannot handle his role in financial regulatory reform while he sits in for ailing Sen. Edward Kennedy on the House's health committee, Politico reports.

23 Jun 2009

Many key lawmakers hold stakes in health industry

"Almost 30 key lawmakers helping draft landmark health-care legislation have financial holdings in the industry, totaling nearly $11 million worth of personal investments in a sector that could be dramatically reshaped by this summer's debate," The Washington Post reports.

15 Jun 2009

Stem cells could halt osteoporosis, promote bone growth

While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great promise to repair bones affected by osteoporosis.

4 Mar 2009