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Activated T-cells promote heart failure after heart attack

Chronic inflammation after a heart attack can promote heart failure and death. University of Alabama at Birmingham researchers have now shown that activated T-cells — part of the immune system's inflammatory response — are both necessary and sufficient to produce such heart failure.

28 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Researchers from Memorial Sloan Kettering Cancer Center have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice.

23 Feb 2017

Researchers find novel, non-invasive approach for diagnosis and prognosis of prostate cancer

In a new paper in Springer's Journal of Materials Science, researchers at Washington State University report a new approach for the effective capture of tumor-derived exosomes from a prostate cancer cell line.

21 Feb 2017

New range of antibodies released by Cambridge Research Biochemicals®

Cambridge Research Biochemicals® (CRB), a longstanding British company specialising in the synthesis of custom peptides and the generation of bespoke antibodies for pharmaceutical and medical research, today announced the release of its new DISCOVERY® Antibodies catalogue. This ties in with the three year anniversary of CRB’s expansion and relocation which took place in January 2014 and secures the company’s position as a key player in the life science industry as we enter 2017.

21 Feb 2017

Early diagnosis does not necessarily result in longer life, study of cancer screenings shows

Physicians and patients like to believe that early detection of cancer extends life, and quality of life. If a cancer is present, you want to know early, right?

20 Feb 2017

Penn researchers find new way to track rare T cells in blood after annual flu vaccine

For most vaccines to work the body needs two cell types - B cells and T helper cells - to make antibodies. B cells are the antibody factories and the T helper cells refine the strength and accuracy of antibodies to home and attack their targets.

20 Feb 2017

Research provides more evidence that mRNA vaccines can protect mice against Zika virus

Vaccine developers have successfully protected mice against Zika by injecting synthetic messenger RNA that encodes for virus proteins into the animals.

17 Feb 2017

Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Taking prostate cancer drug with low-fat breakfast can be effective and less expensive, study finds

Taking one-fourth the standard dose of a widely used drug for prostate cancer with a low-fat breakfast can be as effective - and four times less expensive - as taking the standard dose as recommended: on an empty stomach.

14 Feb 2017

Scientists identify gene variants that predispose children to developing Kawasaki disease

Kawasaki disease (KD) is the most common acquired heart disease in children. Untreated, roughly one-quarter of children with KD develop coronary artery aneurysms -- balloon-like bulges of heart vessels -- that may ultimately result in heart attacks, congestive heart failure or sudden death.

9 Feb 2017

Precision-medicine approach could improve accuracy of PSA-based prostate cancer screening tests

A new study led by researchers at UC San Francisco and Kaiser Permanente has identified genetic predictors of normal prostate-specific antigen (PSA) levels in healthy men, which could be used to improve the accuracy of PSA-based prostate cancer screening tests.

3 Feb 2017

New PET radiotracer effectively detects early and advanced stages of prostate cancer

In the featured article from the February 2017 issue of the Journal of Nuclear Medicine, researchers document the first-in-human application of a new imaging agent to help find prostate cancer in both early and advanced stages and plan treatment.

1 Feb 2017

Valo Therapeutics develops novel oncolytic viral vaccines for treatment of multiple forms of cancer

A spin-out from the University of Helsinki, Valo Therapeutics is developing novel oncolytic viral vaccines for the treatment of multiple forms of cancer.

31 Jan 2017

ALCMI and Scancell collaborate to advance cancer vaccine clinical trials in NSCLC patients

The Addario Lung Cancer Medical Institute, the Bonnie J. Addario Lung Cancer Foundation and Scancell Holdings PLC today announce a collaboration to evaluate the use of Scancell's second innovative cancer vaccine, SCIB2, from its ImmunoBody platform to treat non-small cell lung cancer.

30 Jan 2017

New computer program helps discover 1000 new mutations in blood group genes

1000 new mutations in the blood group genes: that is what physician and former programmer Mattias Möller found in his research study in which he developed new software and investigated blood group genes in 2504 people.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Quest Diagnostics introduces new HBV test service to help evaluate patient’s response to drug therapies

24 Jan 2017

A test to evaluate Hepatitis B therapy launched by Quest Diagnostics

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced the launch of a new test service that helps physicians evaluate a patient’s response to drug therapies used to treat infection with the hepatitis B virus (HBV). The first test of its kind available in the United States, the test is significant because it may help physicians tailor more effective treatments for the up to 2.2 million individuals infected with HBV.

23 Jan 2017

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.

20 Jan 2017