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Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Seattle Genetics, Inc. today announced that Health Canada has issued a Notice of Compliance with conditions (NOC/c), authorizing marketing of ADCETRIS for two lymphoma indications.

1 Feb 2013

Microbiologists discover new pathway to improve vaccines against tuberculosis

A new pathway for improving vaccines against tuberculosis has been discovered by microbiologists at the University at Buffalo in collaboration with researchers at other universities, according to a paper in the journal Mucosal Immunology, published by the Nature group.

1 Feb 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

PaxVax, Inc., which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced positive results in a Phase 1 clinical trial for its oral, replicating adenovirus serotype 4 (Ad4) vector vaccine for H5N1 (avian flu).

31 Jan 2013

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

AvidBiologics Inc., a life sciences company developing antibody-drug conjugates (ADCs), announces the conclusion of an agreement with the National Research Council Canada (NRC) to develop three novel ADCs for the treatment of cancer.

30 Jan 2013

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

OncoPep, Inc. today announced that the Company has initiated a Phase 1/2a clinical trial evaluating PVX-410, a multi-peptide therapeutic cancer vaccine, in patients with smoldering multiple myeloma, an asymptomatic precursor of multiple myeloma, which is an incurable cancer of the plasma cells.

30 Jan 2013

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

ImmunoCellular Therapeutics, Ltd. announced that the US Food and Drug Administration (FDA) has allowed the investigational new drug (IND) application for ICT-140, paving the way for conducting a clinical trial.

30 Jan 2013

New DNA-delivering film holds promise for improving effectiveness of vaccines

Vaccines usually consist of inactivated viruses that prompt the immune system to remember the invader and launch a strong defense if it later encounters the real thing. However, this approach can be too risky with certain viruses, including HIV.

29 Jan 2013

Study sheds new light on why certain people are more likely to suffer from RA

University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis - paving the way to explore new treatments for both arthritis and other autoimmune diseases.

28 Jan 2013

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Seattle Genetics, Inc. today presented interim results from a phase I clinical trial evaluating ASG-5ME for the treatment of metastatic pancreatic ductal adenocarcinoma (PDA) at the American Society of Clinical Oncology (ASCO) 2013 Gastrointestinal Cancers Symposium being held January 24-26, 2013 in San Francisco, CA.

28 Jan 2013

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Infectious diseases in Ghana tend to capture the most attention, but a quiet crisis may soon take over as the country's most threatening epidemic: cancer.

25 Jan 2013

Antibodies essential for dendritic cell maturation

Dendritic cells, or DCs for short, perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface.

23 Jan 2013

Dutasteride decreases risk of biopsy detectable prostate cancer by 22.8%

The four-year REDUCE (REduction by DUtasteride of prostate Cancer Events) clinical study evaluated prostate cancer risk reduction in men taking dutasteride, a 5-alpha-reductase inhibitor (5ARI) typically used to treat enlarged prostate.

22 Jan 2013

Adult onset asthma linked to jobs involving cleaning agents

The strongest evidence seems to be for jobs involving cleaning or cleaning agents, the research suggests. The authors base their findings on the job histories up to the age of 42 of almost 7,500 British adults born in 1958, all of whom were taking part in the National Child Development Study, which is tracking the long term health of more than 11,000 people living in Britain.

22 Jan 2013

Scientists discover role of OTUD7B enzyme as TRAF3's protector

Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.

21 Jan 2013

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells.

21 Jan 2013

Research roundup: Ameliorating physician shortages; Patients' perceptions of bias

The authors note that there is a consensus "that the current shortage of primary care physicians will worsen over the next ten years as the nation's population grows and ages and as insurance coverage expands as a result of the Affordable Care Act." They examine whether workplace changes will impact that assessment.

19 Jan 2013

FDA approves Protein Sciences’ Flublok to prevent seasonal influenza

The US Food and Drug Administration has approved Protein Sciences Corporation's vaccine Flublok for the prevention of seasonal influenza in adults 18 to 49 years of age. Diamyd Medical holds about 8 percent of the shares in Protein Sciences Corporation.

18 Jan 2013

New menu of 61 genetically engineered E. coli strains may improve efficacy of vaccines

Researchers at The University of Texas at Austin have developed a menu of 61 new strains of genetically engineered bacteria that may improve the efficacy of vaccines for diseases such as flu, pertussis, cholera and HPV.

17 Jan 2013

GeneTex to introduce new EasyBlot reagent

GeneTex, a leading manufacturer of high-quality antibodies, is pleased to announce that they will be launching EasyBlot, a new secondary antibody reagent that eliminates the interference that has long plagued immunoprecipitation (IP) experiments when the IP and western blot primary antibodies are from the same host.

16 Jan 2013

Antigen News and Research

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Microbiologists discover new pathway to improve vaccines against tuberculosis

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

NRC, AvidBiologics partner to develop three novel ADCs for treatment of cancer

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

New DNA-delivering film holds promise for improving effectiveness of vaccines

Study sheds new light on why certain people are more likely to suffer from RA

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Antibodies essential for dendritic cell maturation

Dutasteride decreases risk of biopsy detectable prostate cancer by 22.8%

Adult onset asthma linked to jobs involving cleaning agents

Scientists discover role of OTUD7B enzyme as TRAF3's protector

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

Research roundup: Ameliorating physician shortages; Patients' perceptions of bias

FDA approves Protein Sciences’ Flublok to prevent seasonal influenza

New menu of 61 genetically engineered E. coli strains may improve efficacy of vaccines

GeneTex to introduce new EasyBlot reagent

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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