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New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Study introduces a novel dry powder aerosol COVID-19 vaccine, showing its effectiveness in inducing strong immune responses and offering protection against various SARS-CoV-2 strains, including Omicron.

15 Dec 2023

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

Study evaluates the single-dose intranasal spray vaccine dNS1-RBD, finding it effective against symptomatic COVID-19, particularly in reducing severe symptoms and respiratory issues.

15 Dec 2023

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

14 Dec 2023

New study highlights the need for advanced pneumococcal vaccines in the wake of pre-COVID data

The risk factors associated with CAP caused by serotypes in the different pneumococcal vaccines.

14 Dec 2023

U.S. veterans' study reveals key insights into Long COVID and protective role of vaccination

Study examines the clinical characteristics and trends of post-COVID-19 condition (PCC) in U.S. veterans, showing the protective effect of vaccination and the need for precise symptom documentation for effective research and clinical care.

12 Dec 2023

Nanoparticle vaccines can help fight zoonotic viral diseases

Announcing a new article publication for Zoonoses journal. Vaccines are the most promising tools for maintaining public health.

12 Dec 2023

Scientists develop new system to display epitopes in mammal cells for immunization studies

A new paper in Biology Methods & Protocols, published by Oxford University Press, indicates that researchers in Germany have developed a new system to display epitopes in mammal cells for immunization studies.

12 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm.

11 Dec 2023

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into remission before the cell therapy begins.

11 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

New insights into the structures formed during antibody aggregation through 3D domain swapping

Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development.

8 Dec 2023

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.

7 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

These programs put unused prescription drugs in the hands of patients in need

On a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs to treat her high blood pressure and arm seizures.

6 Dec 2023

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Researchers assessed ethnic and racial differences in novel hormonal therapy (NHT) use among advanced prostate cancer (PCa) patients.

6 Dec 2023

New mechanism revealed for how group A Streptococcus infection reduces type 1 diabetes risk

Researchers have discovered the novel mechanism that underlies a previously reported observation that infection by group A Streptococcus bacteria reduces the risk of later developing Type 1 diabetes.

5 Dec 2023

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

The safety, efficacy, and immunogenicity of a mRNA-based vaccine.

5 Dec 2023

Antigen News and Research

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

New study highlights the need for advanced pneumococcal vaccines in the wake of pre-COVID data

U.S. veterans' study reveals key insights into Long COVID and protective role of vaccination

Nanoparticle vaccines can help fight zoonotic viral diseases

Scientists develop new system to display epitopes in mammal cells for immunization studies

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

New insights into the structures formed during antibody aggregation through 3D domain swapping

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

These programs put unused prescription drugs in the hands of patients in need

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

New mechanism revealed for how group A Streptococcus infection reduces type 1 diabetes risk

Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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