Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

New drug targets may fight tuberculosis and other bacterial infections in novel way

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

28 Dec 2007

Paradigm shift in TB: virulence factors, not antibiotics

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

27 Dec 2007

Poultry workers at greater risk of carrying antibiotic-resistant E. coli

Poultry workers in the United States are 32 times more likely to carry E. coli bacteria resistant to the commonly used antibiotic, gentamicin, than others outside the poultry industry, according to a recent study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health.

18 Dec 2007

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Antibacterial chemical in bath soaps disrupts hormone activities

A new UC Davis study shows that a common antibacterial chemical added to bath soaps can alter hormonal activity in rats and in human cells in the laboratory - and does so by a previously unreported mechanism.

10 Dec 2007

Purified bacterial extract sprayed into lungs ramps up innate immune system

A purified extract prepared from a common microbe and delivered to the lungs of laboratory mice in a spray set off a healthy immune response and provided powerful protection against all four major classes of pathogens including those responsible for anthrax and bubonic plague, according to a presentation at the American Society for Cell Biology's 47th Annual Meeting.

4 Dec 2007

Cethromycin achieves all endpoints in second pivotal Phase III Trial for treatment for pneumonia

Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), today announced positive results from Trial CL-05, the second of two pivotal phase III clinical trials designed to assess the safety and effectiveness of cethromycin, a novel once-a-day oral antibiotic for the treatment of mild-to-moderate community acquired pneumonia (CAP), the sixth leading cause of death in the United States.

16 Nov 2007

FDA clears breathing tube coated with a thin layer of silver

The U.S. Food and Drug Administration has announced that it has cleared for marketing a breathing tube coated with a thin layer of silver. The coating, a material known to have antimicrobial properties, reduces the risk that patients on ventilators will acquire pneumonia while in the hospital.

13 Nov 2007

Psychological stress increases susceptibility to skin infections in mice

It is well known that being stressed increases our susceptibility to infections by impairing the function of our immune system, but the molecular links between stress and diminished immune function have not been determined.

2 Nov 2007

Infectious diseases experts applaud STAAR Act

With methicillin-resistant Staphylococcus aureus (MRSA) infections, extensively drug-resistant tuberculosis, and other "bad bugs" routinely making headlines, infectious diseases physicians are applauding Sens.

1 Nov 2007

What makes some clays powerful antimicrobial agents?

With funding from the National Institutes of Health-National Center for Complementary and Alternative Medicine, the UB geologists are studying the surface characteristics of a broad range of naturally occurring antimicrobial clays, including some clays from France to determine why they are such effective killers of bacteria.

29 Oct 2007

Promising new tuberculosis drug given special status

Approximately one-third of the world's population is infected with Mycobacterium tuberculosis, the bacterium that causes TB, and an estimated 1.6 million people died of the disease in 2005.

25 Oct 2007

Honey for wound healing

Surgeons are being advised to consider the supermarket as well as the drugs cupboard when it comes to effective wound healing, according to a research review published in the October issue of IJCP, the International Journal of Clinical Practice.

18 Oct 2007

Researchers take on E. coli 0157 and salmonella

Understanding the ecology of two dangerous foodborne pathogens and devising ways to combat them is a big job.

17 Oct 2007

Feline virus, antiviral drug studied to understand drug resistance

Researchers at Ohio State will spend the next two years testing their theories about just how an AIDS-like virus in cats is able to resist the powerful medicines that are thrown against it.

10 Oct 2007

Gates Foundation leads the charge against tuberculosis with Northeastern University

Northeastern University announced that Dr. Kim Lewis, Professor of Biology and Director of the Antimicrobial Center, is among the recipients of $280 million in grants the Bill & Melinda Gates Foundation has dedicated to help support the research and speed the development of TB vaccines, diagnostic tests, and treatments.

4 Oct 2007

Caribbean health authorities promise to reduce healthcare-associated infections

Health authorities from the Caribbean say they will work to reduce healthcare-associated infections through a series of actions that include getting healthcare providers to improve hand hygiene.

2 Oct 2007

Infectious Diseases Society of America strongly supports the STAAR Act

With extensively drug-resistant tuberculosis, life-threatening drug-resistant respiratory and skin infections, and other "bad bugs" routinely making headlines, infectious diseases physicians are applauding Rep. Jim Matheson (D-UT) and Rep. Michael Ferguson (R-NJ) for introducing H.R. 3697, the Strategies To Address Antimicrobial Resistance (STAAR) Act.

29 Sep 2007

New bioengineered antimicrobials help cystic fibrosis patients breathe easier

By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections.

25 Sep 2007

New topical lotion safely treats nail fungus without side effects

A new topical lotion that penetrates the skin deeply enough to target and eliminate serious skin infections, but without being systemically absorbed, has shown a high degree of safety and tolerability in patients with onychomycosis, or toenail fungus, a new study has shown.

25 Sep 2007