Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

WHO and its partners call for increased research to improve patient safety

They emphasized the need for intensified research at an international conference that opened today in Porto, Portugal. The conference on Patient safety research: shaping the European agenda will examine evidence showing that harm from medical care poses a substantial burden in terms of suffering and death in Europe and around the world.

25 Sep 2007

Soap and warm water best for battling Clostridium difficile

Hospitals world-wide battle nosocomial infections on a daily basis.

21 Sep 2007

Scientists decipher mechanism behind antimicrobial 'hole punchers'

In the battle against bacteria, researchers have scored a direct hit.

21 Sep 2007

Drug resistance gene has spread from East Coast to Midwest

A resistance gene that allows bacteria to beat an important class of antibiotics has started to appear in microorganisms taken from Midwestern patients, according to researchers at Washington University School of Medicine in St. Louis.

20 Sep 2007

Review of antimicrobials for acute rhinosinusitis

Acute bacterial rhinosinusitis in adults is a common malady, with between 30 to 35 million cases a year.

18 Sep 2007

Moxifloxacin drug combo speeds up treatment of tuberculosis

A team of tuberculosis (TB) experts at Johns Hopkins and in Brazil have evidence that substituting the antibiotic moxifloxacin in the regimen of drugs used to treat the highly contagious form of lung disease could dramatically shorten the time needed to cure the illness from six months to four.

18 Sep 2007

FDA warns Procter and Gamble on hand sanitizer marketing

The U.S. Food and Drug Administration (FDA) has sent a warning letter to Procter & Gamble for making unlawful claims about its Vicks Early Defense Foaming Hand Sanitizer (Early Defense) product.

18 Sep 2007

LL37 peptide provides a new potential target for autoimmune disease

A human peptide that acts as a natural antibiotic against invading microbes can also bind to the body's own DNA and trigger an immune response in the absence of an infection, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in an early online publication in Nature.

17 Sep 2007

Organisms found on contact lenses provide clues to corneal eye infections

Cultures of contact lenses may sometimes identify the organisms involved in cases of corneal eye infection, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

Bad news for disease-causing bacteria!

Scientists have what could be some very bad news for disease-causing bacteria. All three major classes of antibiotics that kill infectious bacteria do so in part by ramping up the production of harmful free radicals, researchers report in the September 7, 2007, issue of Cell, a publication of Cell Press.

10 Sep 2007

Quick microchip test for dangerous and drug resistant bacteria in clinical samples

Researchers at the Veterinary Laboratories Agency in Surrey have developed microchips capable of quickly and cheaply identifying dangerous and drug resistant bacteria in clinical samples, scientists announced (Wednesday 5 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

5 Sep 2007

Ardea Biosciences completes phase 1 trials of HIV drug RDEA806

Ardea Biosciences, Inc. has announced that it has successfully completed Phase 1 single-ascending-dose, multiple-ascending-dose, food-effect, and drug-interaction studies of RDEA806, a novel HIV non-nucleoside reverse transcriptase inhibitor (NNRTI), in healthy volunteers.

5 Sep 2007

Irish study to look at how bacteria, Yersinia enterocolitica, enters the food chain

Monitoring of pig carcasses and pig meat in slaughterhouses, butchers' premises and retail outlets will be undertaken in Ireland over the next two years in an attempt to determine how a human disease causing bacteria, Yersinia enterocolitica, enters the food chain, scientists announced today (Tuesday 4 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

4 Sep 2007

Carbon nanotubes to fight E. coli

Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir.

30 Aug 2007

Researchers discover nature uses a recurring molecular strategy to defend against infection

With infections increasingly resistant to even the most modern antibiotics, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) report in the September issue of Nature Reviews Microbiology on new clues they have uncovered in immune system molecules that defend against infection.

30 Aug 2007

Gamma globulin effective treatment for pinkeye

Gamma globulin, a type of antibody isolated from blood samples that used to be routinely given to health care workers and international travelers to protect them from infectious diseases, is a highly effective treatment for pinkeye with little apparent toxicity, according to a study by researchers at the University of Pittsburgh School of Medicine.

29 Aug 2007

Global public health security in the 21st century

More than at any previous time in history, global public health security depends on international cooperation and the willingness of all countries to act effectively in tackling new and emerging threats.

23 Aug 2007

Natural antimicrobial agents for food safety

Two items high on the list of public concerns are the need for greater food safety and a growing demand for natural or organic food products.

22 Aug 2007

Pigs key to understanding antibiotic resistant bacteria

NSW Department of Primary Industries (NSW DPI) Immunology & Molecular Diagnostic Research Unit Team Leader, Dr James Chin, says it is commonly believed that each time an antibiotic is used only pathogens or disease-causing bacteria will be killed.

1 Aug 2007

New treatment to combat bowel infection among the elderly

Scientists at the Alimentary Pharmabiotic Centre (APC), based in University College Cork (UCC) and Teagasc’s Moorepark Food Research Centre, are researching a new treatment to combat the increasing incidences of hospital acquired diarrhoea which has become a major problem in hospitals, nursing homes and facilities for the elderly.

1 Aug 2007