Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

Two antimicrobial drug developing companies evaluate new approach for treating bacterial infections

Chaperone Technologies, Inc. and MerLion Pharmaceuticals Pte Ltd., both privately-held companies developing new antimicrobial drugs, announced today that they are together evaluating a unique approach for the treatment of resistant and life-threatening bacterial infections.

4 Dec 2009

Transatlantic task force to address antibiotic resistance established, experts welcome initiative

Experts on both sides of the Atlantic applaud President Barack Obama and Swedish Prime Minister Fredrik Reinfeldt, representing the European Union (EU) Presidency, for establishing a transatlantic task force to address antibiotic resistance, an urgent and growing problem that threatens patient safety and public health worldwide.

7 Nov 2009

Experts applaud the EU Presidency for establishing a transatlantic task force to address antibiotic resistance

7 Nov 2009

International human migration needs to be factored into infectious disease policy

When people travel, bacteria and other infectious agents travel with them. As about a billion people cross international borders each year, many more billions of the bugs come along for the ride.

19 Oct 2009

New clinical trials to address the effectiveness of antimicrobial drugs

Scientists are addressing the threat of antimicrobial drug resistance by launching two new clinical trials aimed at prolonging the effectiveness of currently available antibacterial drugs. The concept underlying both studies: Less is more.

3 Sep 2009

Higher drug doses needed to defeat tuberculosis in overweight and obese

The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.

30 Jul 2009

The effects of antimicrobial therapy on bacterial vaginosis in non-pregnant women

Antimicrobial treatments for bacterial vaginosis (BV) are effective, but taking lactobacillus tablets alongside metronidazole antibiotic therapy increases effectiveness over taking this antibiotic alone, according to a Cochrane Systematic Review. The researchers also concluded that intravaginal lactobacillus was as effective as oral metronidazole, although they did note unexplained drop-outs from the trials.

7 Jul 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

Promising antimicrobial agent kills viruses, stimulates immune system

A promising antimicrobial agent already known to kill bacteria can also kill viruses and stimulate the innate immune system, according to researchers at National Jewish Health.

4 Jun 2009

Cimzia approved in U.S. for rheumatoid arthritis

UCB announced today that the U.S. Food and Drug Administration (FDA) approved Cimzia, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).

13 May 2009

New kind of treatment for sexually transmitted diseases

Yale researchers describe a breakthrough in safe and effective administration of potential antiviral drugs - small interfering RNA (siRNA) molecules that silence genes - the first step in development of a new kind of treatment for sexually transmitted diseases (STDs). The work is reported May 4 as an advance online publication of Nature Materials.

3 May 2009

Risk factors identified for ventilator-associated pneumonia

Ventilator-associated pneumonia (VAP) is the main cause of nosocomial infection in patients undergoing major heart surgery.

29 Apr 2009

Study finds multidrug-resistant gram-negative bacteria high in long-term care

The prevalence of a certain form of drug-resistant bacteria, called multidrug-resistant gram-negative (MDRGN) organisms, far surpassed that of two other common antimicrobial-resistant infections in long-term care facilities, according to a study conducted by researchers at Hebrew SeniorLife's Institute for Aging Research.

12 Apr 2009

Deficiency in vitamin D may exacerbate autoimmune disease

Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease.

9 Apr 2009

Coartem tablets approved in U.S. to treat malaria

The U.S. Food and Drug Administration has approved Coartem tablets (artemether and lumefantrine) for the treatment of acute, uncomplicated malaria infections in adults and children weighing at least five kilograms (approximately 11 pounds).

8 Apr 2009

New understanding on how probiotics can prevent disease

Using probiotics successfully against a number of animal diseases has helped scientists from University College Cork, Ireland to understand some of the ways in which they work, which could lead to them using probiotics to prevent and even to treat human diseases.

1 Apr 2009

A magic bullet for superbugs

Attaching an antimicrobial drug, which is activated by light, to a peptide that binds to bacteria and stops them making toxins, produced a "magic bullet" that was highly effective at killing the superbug, methicillin-resistant Staphylococcus aureus (MRSA).

1 Apr 2009