Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

Vitamin D enhances placental innate immunity

In a paper available at the online site of the journal Biology of Reproduction, a team of UCLA researchers reports for the first time that vitamin D induces immune responses in placental tissues by stimulating production of the antimicrobial protein cathelicidin.

1 Dec 2008

Six bad bugs increasingly escaping effects of antibiotics

Infectious disease experts warn that new drugs are urgently needed to treat six drug-resistant bacteria that cause most hospital infections and increasingly escape the effects of antibiotics.

1 Dec 2008

Clear seasonal variation in bacterial infections

In the same way that winter is commonly known to be the "flu season," a new study suggests that the dog days of summer may well be the "bacterial infection" season.

26 Nov 2008

Study looks at exposure to antibiotic-resistant bacteria from transportation of poultry

Researchers at the Johns Hopkins Bloomberg School of Public Health have found evidence of a novel pathway for potential human exposure to antibiotic-resistant bacteria from intensively raised poultry-driving behind the trucks transporting broiler chickens from farm to slaughterhouse.

24 Nov 2008

Long-term use of a macrolide antibiotic reduce COPD exacerbations, raise questions

Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study.

21 Nov 2008

How household bleach kills bacteria

Despite the fact that household bleach is commonly used as a disinfectant, exactly how it works to fight bacteria remained an open question.

16 Nov 2008

Swiss approval for Zevtera in treatment of complicated skin and soft tissue infections

Swissmedic, the Swiss agency for therapeutic products, has approved Zevtera (ceftobiprole medocaril) for the treatment of complicated skin and soft tissue infections, including diabetic foot infections which have not spread to the bone.

13 Nov 2008

U.S. 'super bugs' invading several Colombian cities

Two clones of highly antibiotic-resistant organism strains, which previously had only been identified in the United States, are now causing serious sickness and death in several Colombian cities including the capital Bogota, say researchers at The University of Texas Medical School at Houston.

12 Nov 2008

Antibacterial drug use increases at academic medical centers

Antibacterial drug use appears to have increased at academic medical centers between 2002 and 2006, driven primarily by greater use of broad-spectrum agents and the antibiotic vancomycin, according to a report in the Nov. 10 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

10 Nov 2008

New silver coated anti-microbial barrier dressing receives Canadian approval

NUCRYST Pharmaceuticals, a developer and manufacturer of medical products that fight infection and inflammation, and the Advanced Wound Management division of Smith & Nephew plc announced today that Health Canada granted marketing approval for Acticoat Flex barrier dressing for wounds that require up to seven days of sustained antimicrobial activity.

8 Nov 2008

Accelr8 announces study results with BACcel diagnostic system for broad resistance in gram-negative pathogens

Accelr8 Technology Corporation announced study results today that were presented at the joint sessions of the 48 th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC, www.icaac.org) and the Infectious Diseases Society of America (IDSA, www.idsociety.org), October 25-29 in Washington, DC.

7 Nov 2008

Protect yourself from flu by wearing a mask and washing your hands

In what has been termed a landmark new study, it is suggested that wearing masks and washing hands prevents the spread of flu-like symptoms.

28 Oct 2008

New strategy to treat human infections caused by the yeast Candida albicans

Researchers at Georgetown University Medical Center (GUMC) have successfully tested a genetic strategy designed to improve treatment of human infections caused by the yeast Candida albicans, ranging from diaper rash, vaginitis, oral infections (or thrush which is common in HIV/AIDS patients), as well as invasive, blood-borne and life-threatening diseases.

27 Oct 2008

NanoBio demonstrates new topical approach to treating nail fungus that circumvents problems with current therapy

A novel topical therapy for nail fungus, NB-002, has demonstrated a new topical approach to healing nail fungus by penetrating skin pores and diffusing through the skin that surrounds the entire nail plate, according to a study conducted by NanoBio Corporation.

27 Oct 2008

Rapid HIV testing in the emergency department boosts diagnoses, screening

One in every 50 people screened for a suspected sexually transmitted infection (STI) in the Emergency Department at Henry Ford Hospital was found to be infected with HIV using a rapid blood sample screening test.

26 Oct 2008

Targanta Therapeutics presents preclinical data on Oritavancin against Clostridium difficile infection

Targanta Therapeutics Corporation has released the in vivo data from a preclinical study comparing the activity of its antibiotic drug candidate, oritavancin, to vancomycin in a hamster model of Clostridium difficile infection.

26 Oct 2008

High dose flu vaccine boosts immune response in elderly

Giving people age 65 and older a dose four times larger than the standard flu vaccine boosts the amount of antibodies in their blood to levels considered protective against the flu, more so than the standard flu vaccine does. The findings from a study of nearly 4,000 people were presented Oct. 26 at a national meeting on infectious diseases.

26 Oct 2008

Why do women typically experience poorer dental health than men?

Reproduction pressures and rising fertility explain why women suffered a more rapid decline in dental health than did men as humans transitioned from hunter-and-gatherers to farmers and more sedentary pursuits, says a University of Oregon anthropologist.

14 Oct 2008

Steroids aid recovery from pneumonia, UT Southwestern researchers say

Adding corticosteroids to traditional antimicrobial therapy might help people with pneumonia recover more quickly than with antibiotics alone, UT Southwestern Medical Center scientists have found.

14 Oct 2008

The healing power of honey for wounds

Since ancient times honey has been valued for its health benefits and is even mentioned in the Bible and it has had a prominent a role in the customs and diets of many cultures for centuries.

12 Oct 2008