Antimicrobial Drug News and Research

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Antimicrobials are substance that kills microorganisms such as bacteria or mold, or stops them from growing and causing disease.

Mud may help fight MRSA infections

Scientists in Arizona report that minerals from clay could form the basis of a new generation of inexpensive, highly-effective antimicrobials for fighting MRSA infections that are moving out of health care settings and into the community.

7 Apr 2008

Alligator blood may provide a source of powerful new antibiotics

Despite their reputation for deadly attacks on humans and pets, alligators are wiggling their way toward a new role as potential lifesavers in medicine, biochemists in Louisiana reported today at the 235th national meeting of the American Chemical Society.

7 Apr 2008

Alligator blood extract promises to help fight superbugs

Biochemists from Louisiana in the U.S. say blood from alligators could help fight deadly 'superbugs' and other infections.

7 Apr 2008

Lyme disease - a tough nut to crack!

The bacteria that cause Lyme disease, the most common tick-borne illness in the United States, can linger in mouse tissues long after a full round of antibiotic treatment is completed, report researchers from the University of California, Davis.

2 Apr 2008

Caspase-12: MUHC researcher finds new defense mechanism against intestinal inflammation

The body's first line of defence against pathogenic bacteria that we ingest may not be the immune system but rather the cells that line the intestine.

13 Mar 2008

New findings do not support recommendation for universal screening on hospital admission for MRSA

New findings do not support the recommendation for universal screening on hospital admission for methicillin-resistant Staphylococcus aureus (MRSA) to reduce the rate of hospital-acquired infections in surgical patients, according to a study in the March 12 issue of JAMA.

12 Mar 2008

Tackling antimicrobial resistance

Drug resistance is making many diseases increasingly difficult and sometimes impossible to treat, according to Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

11 Mar 2008

Nasal vaccine for smallpox protects animals against 77 times the potentially lethal dose of smallpox

Scientists at NanoBio Corporation and the University of Michigan have demonstrated their nasally delivered vaccinia vaccine can protect animals against 77 times the potentially lethal dose of smallpox, and without the safety risks of current vaccines for smallpox.

27 Feb 2008

Scientists identify proteins that help bacteria put up a fight

Scientists have identified the role of two proteins that contribute to disease-causing bacteria cells' versatility in resisting certain classes of antibiotics.

27 Feb 2008

Questions over use of antibiotics in 'end of life' care

Antibiotics appear to be frequently prescribed to individuals with advanced dementia in nursing homes, especially in the two weeks before death, according to a report in the February 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Feb 2008

Newly discovered ERK pathway proteins related to CagA induced disease

Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer.

25 Feb 2008

Researchers examine animal antibiotic resistance, possible human link

It's bad enough when pathogenic bacteria work their way into the animal food supply.

20 Feb 2008

Mathematical approach to tackle dual-resistant hospital infections

A mathematical model that looks at different strategies for curbing hospital-acquired infections suggests that antimicrobial cycling and patient isolation may be effective approaches when patients are harboring dual-resistant bacteria.

17 Feb 2008

Researchers find new U.S. trend in antibiotic resistance

A research team from The University of Texas Health Science Center at San Antonio, examining bacterial isolates obtained in hospital and non-hospital clinical settings between 2000 and 2006, has identified drug-resistant strains of E. coli and Klebsiella bacteria in more than 50 blood, urine and respiratory samples.

11 Feb 2008

Unique fungal collection could hold key to future antibiotics

Scientists at Royal Holloway, University of London have joined forces with CABI to establish a facility to screen for potential new antibiotics.

23 Jan 2008

New compounds for treating tuberculosis and malaria

University of Navarra PhD in chemistry researcher, Esther Vicente, has discovered new compounds active for treating tuberculosis and malaria.

23 Jan 2008

Studies highlight MRSA evolution and resilience

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are caused primarily by a single strain USA300 of an evolving bacterium that has spread with "extraordinary transmissibility" throughout the United States during the past five years, according to a new study led by National Institutes of Health (NIH) scientists.

22 Jan 2008

Brits get to grips with superbugs

The British government, as part of it's fight against 'superbugs' such as methicillin-resistant Staphylococcus aureu (MRSA) and Clostridium difficile, has promised every hospital the funds to recruit four specialist nurses to help curb the infections.

10 Jan 2008

Urinary tract infections from the catheter - most common hospital-acquired infection

One in four Americans in the hospital right now has a urinary catheter. One percent of them will get a urinary tract infection from that catheter.

4 Jan 2008

BD Diagnostics announces FDA clearance of test to identify superbug

BD Diagnostics, a segment of BD (Becton, Dickinson and Company), has announced that it received clearance from the U.S. Food and Drug Administration (FDA) for the BD GeneOhm StaphSR assay.

From BD (Becton, Dickinson and Company) 3 Jan 2008