Antiphospholipid Syndrome News and Research

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CHEST releases new clinical guidelines for management of venous thromboembolism

The American College of Chest Physicians recently released new clinical guidelines for venous thromboembolism management, "Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel," that provides 29 recommendations on 17 Patients, Interventions, Comparators, Outcomes (PICO) questions, four of which have not been addressed previously.

5 Aug 2021

Functional autoantibody in COVID-19 contributes to the 'firestorm' of blood clots and inflammation

Researchers at Michigan Medicine have discovered yet another functional autoantibody in COVID-19 patients that contributes to the disease's development and the "firestorm" of blood clots and inflammation it induces.

19 Jul 2021

FDA approves oral pellets to treat children with venous thromboembolism

Today, the U.S. Food and Drug Administration approved Pradaxa (dabigatran etexilate) oral pellets to treat children 3 months to less than 12 years old with venous thromboembolism (a condition where blood clots form in the veins) directly after they have been treated with a blood thinner given by injection for at least five days.

21 Jun 2021

New study uncovers potential therapeutic target for lupus

A recent study published in JCI found that a neutrophil's endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus.

26 Mar 2021

COVID-19 may alter host proteins to cause autoimmunity

To better understand the transient and chronic autoimmune symptoms caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, researchers from Memorial Sloan Kettering Cancer Center, Guizhou Medical University, and biotech company Curandis embarked on an endeavor to establish a comprehensive autoantigenome for COVID19.

23 Feb 2021

Main bioactive compound of ginger root may protect against autoimmune disease progression

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

6 Jan 2021

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

An international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classification criteria for clinical research of antiphospholipid syndrome (APS), a life-threatening autoimmune clotting disorder.

17 Dec 2020

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

At this year's American College of Rheumatology virtual meeting, Hospital for Special Surgery (HSS) presented exciting research related to rheumatology and orthopedic surgery.

10 Nov 2020

Study identifies new cause of COVID-19 blood clots

Blood clots continue to wreak havoc for patients with severe COVID-19 infection, and a new study explains what may spark them in up to half of patients.

2 Nov 2020

Neo-self antibody could be a major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases (RIMD) have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

Researchers find prothrombotic antibodies in patients with COVID-19

Even as the COVID-19 pandemic continues to spread across the world, researchers are still trying to understand the many ways in which it can manifest and its pathogenesis. A new report published on the preprint server medRxiv* in June 2020 shows that one possible mechanism of disease in COVID-19 is the production of antiphospholipid antibodies.

19 Jun 2020

Anticardiolipin antibodies and COVID-19

A new study has shown that anticardiolipin antibodies are associated with the novel coronavirus infection or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.

10 Jun 2020

Hyperferritinemia associated with increased illness severity in COVID-19

Yehuda Shoenfeld is the world's leading expert in the research, treatment and prevention of autoimmune diseases.

22 Apr 2020

Common antibodies associated with myocardial infarction

Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity, a study from Karolinska Institutet in Sweden published in The Annals of Internal Medicine reports.

23 Oct 2018

Inova Diagnostics announces FDA clearance for QUANTA Flash assays, QUANTA Flash Beta-2GP1 Domain1

Inova Diagnostics, a worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, announced today that it has received 510(k) clearance by the U.S. Food and Drug Administration on key QUANTA Flash assays for use with Inova Diagnostics' BIO-FLASH chemiluminescent analyzer for autoimmune testing.

20 Jul 2015

Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Researchers at UT-Southwestern Medical Center have found that the most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels. Individuals with another variant, called apoE4, do not get the benefit of this repair, putting them at higher risk for cardiovascular disease.

18 Sep 2014

Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Epilepsy is a group of neurological disorders often characterized by seizures and cognitive impairment due to electrical disturbances in the brain.

From Quest Diagnostics 14 May 2014

Patients with autoimmune disease have 3.8-fold increased risk of developing epilepsy

Patients with an autoimmune disease have a 3.8-fold increased risk of developing epilepsy, according to a new population-level study from Boston Children's Hospital based on health insurance claim data.

1 Apr 2014

Anti-malaria drug combination may help prevent pregnancy complications in women with lupus

An anti-malaria drug combination might be useful in helping to prevent pregnancy complications in women with lupus and the related disorder antiphospholipid syndrome, Yale School of Medicine researchers have found in a new study published in the American Journal of Reproductive Immunology.

23 Jan 2014

Biomarker may predict poor pregnancy outcomes in lupus patients

Researchers at Hospital for Special Surgery in New York City have identified a biomarker that may predict poor pregnancy outcomes in lupus patients.

28 Oct 2013