Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.
Researchers have developed a mouse strain in which the abnormal activity of the dopamine machinery in a specific part of the brain causes cognitive and behavioral impairments mimicking those in human schizophrenics.
Researchers at the Brigham and Women's Hospital in Boston are saying that many of the older drugs designed to treat mental problems such as delirium, agitation and psychosis may be even more hazardous to the elderly than newer medicines that now carry U.S. government warnings.
LGC, Europe's leading independent analytical laboratory providing advanced chemical, biochemical and forensic analysis, has announced an exclusive agreement with King’s College London to offer the first pharmacogenetic screening service which will predict whether a patient with schizophrenia will respond positively to the antipsychotic drug clozapine.
A study in youth who are missing part of a chromosome is further implicating a suspect gene in schizophrenia.
Some newer antipsychotic medications may be associated with a small increased risk of death when used to treat elderly dementia patients, psychiatrists at Johns Hopkins warn.
Atypical antipsychotic drugs seem to confer a small increased risk for death when used in people with dementia, concludes a team of researchers from the Keck School of Medicine of the University of Southern California in a meta-analysis of 15 clinical trials published in the October 19 issue of the JAMA: The Journal of the American Medical Association.
A large study funded by NIH's National Institute of Mental Health (NIMH) provides, for the first time, detailed information comparing the effectiveness and side effects of five medications - both new and older medications - that are currently used to treat people with schizophrenia.
...yet their knowledge of diabetes was generally poor and significantly lower than people without mental illness, according to a new study.
Spectrum Pharmaceuticals has announced that it has received from the U.S. Patent and Trademark Office (USPTO) a Notice of Allowance for its patent application for SPI-339 entitled "Methods for Treating Cognitive/Attention Deficit Disorders Using Tetrahydroindolone Analogues and Derivatives."
The condition (bipolar I and II) affects approximately 8 million Americans, who have relied on a combination of drugs to manage their symptoms, and who remain at high risk of committing suicide because of the difficulty in treating the disorder.
In a study sponsored by the U.S. National Institute of Mental Health, and conducted over a number of sites, it has been found that the antipsychotic drug risperidone is a safe, effective treatment for children with autism who display tantrums, aggression and often self-injure.
A new study, published in the journal Human Psychopharmacology: Clinical and Experimental, shows that the atypical antipsychotic Seroquel (quetiapine), may be an effective treatment option for patients with schizophrenia who exhibit aggressive behaviour during psychotic episodes.
"The FDA's review today of BiDil could make it the first drug approved specifically for African Americans and marks the end of 'one-size-fits-all' medicine," said Dr. Jane L. Delgado, President and CEO of the National Alliance for Hispanic Health (the Alliance), the nation's leading Hispanic health advocacy group.
People with schizophrenia often die prematurely. However researchers from the University of Glasgow and NHS Greater Glasgow assert that much of the excess mortality of schizophrenia is preventable through lifestyle changes and the treatment of common diseases.
Clues about how a suspect version of a gene may slightly increase risk for schizophrenia are emerging from a brain imaging study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). The gene variant produced a telltale pattern of activity linked to production of a key brain messenger chemical.
Shock therapy, a controversial practice conjuring frightening images of behavior control, still has a place in schizophrenia treatment, a newly updated research review shows.
The Food and Drug Administration (FDA) has issued a public health advisory to alert health care providers, patients, and patient caregivers to new safety information concerning an unapproved (i.e., “off-label”) use of certain drugs called “atypical antipsychotic drugs.”
The Food and Drug Administration (FDA) has issued a public health advisory to health care providers, patients, and caregivers to alert them to new safety information about the use of certain unapproved or off label drugs which come under the category of “atypical antipsychotic drugs.”
An Oregon Health & Science University researcher is among an international team closing in on why many people with schizophrenia and other psychotic disorders are "supersensitive" to the powerful neurotransmitter dopamine.
A new brain imaging study of recently diagnosed schizophrenia patients has found, for the first time, that the loss of gray matter typically experienced by patients can be prevented by one of the new atypical antipsychotic drugs, olanzapine, but not by haloperidol, an older, conventional drug.