Antipsychotic News and Research

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Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.

Nurse care for schizophrenia patients

Drug and psychosocial interventions for the symptoms of schizophrenic disorders contribute to a lower incidence and prevalence of schizophrenia. Nurses will be able to offer better care through the use of nursing models and theories in the care of Schizophrenics.

6 May 2008

Antipsychotic drugs increase risk of developing pneumonia in elderly

Elderly patients who use antipsychotic drugs have a 60 percent increased risk of developing pneumonia compared to non-users.

16 Apr 2008

Treatment with an anti-psychotic drug found to cause changes in metabolism earlier than expected

Schizophrenia is a complex type of psychotic mental illness characterized by thoughts that are uncoupled from reality.

8 Apr 2008

Aripiprazole has potential for treating alcohol dependence

Aripiprazole is currently approved to treat bipolar disorder as well as schizophrenia. A new study has found that it significantly and dose-dependently increases the sedative effects of alcohol and, to a lesser degree, decreases the euphoric effects of alcohol. Future research will need to examine the beneficial versus the side effects of aripiprazole for treatment of alcohol dependence.

4 Apr 2008

Restrictive drug policies often cause schizophrenic patients to discontinue medication

Policies requiring authorization before physicians can prescribe newer medications to schizophrenic patients may be counter-productive.

2 Apr 2008

Researchers may have found test for depression

Researchers from the University of Illinois at Chicago College of Medicine have discovered that a change in the location of a protein in the brain could serve as a biomarker for depression, allowing a simple, rapid, laboratory test to identify patients with depression and to determine whether a particular antidepressant therapy will provide a successful response.

12 Mar 2008

New discovery could change future diagnosis and therapy of depression

12 Mar 2008

Genetic variations increase risk of anxiety disorders

Massachusetts General Hospital (MGH) researchers - in collaboration with scientists at the University of California at San Diego and Yale University - have discovered perhaps the strongest evidence yet linking variation in a particular gene with anxiety-related traits.

4 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Abilify (aripiprazole) approved for acute treatment of bipolar I disorder in adolescents

Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company has announced that the U.S. Food and Drug Administration (FDA) approved the supplemental New Drug Application for ABILIFY (aripiprazole) for the acute treatment of manic and mixed episodes associated with Bipolar I Disorder, with or without psychotic features in pediatric patients (10 to 17 years old).

1 Mar 2008

Lilly knocked back by FDA on Zyprexa for schizophrenia treatment

Eli Lilly and Company has received a not approvable letter from the U.S. Food and Drug Administration for Zyprexa long-acting injection (olanzapine LAI) for the treatment and maintenance treatment of schizophrenia in adults, the company announced.

28 Feb 2008

Treatment of children and adolescents with schizophrenia

There is a wealth of scientific literature available on the treatment of adults diagnosed with schizophrenia.

28 Feb 2008

Discovery of new receptor complex in brain - better understanding of how hallucinations occur

Mount Sinai researchers have identified a new receptor complex in the brain that responds to several types of antipsychotic drugs used to treat schizophrenia and also reacts to hallucinogenic drugs such as LSD.

27 Feb 2008

Siblings of schizophrenia patients display subtle shape abnormalities in brain

Subtle malformations in the brains of patients with schizophrenia also tend to occur in their healthy siblings, according to investigators at the Silvio Conte Center for the Neuroscience of Mental Disorders at Washington University School of Medicine in St. Louis. Shape abnormalities were found in the brain's thalamus.

20 Feb 2008

Study suggests Risperidone long-acting injection combined with standard treatment helped delay time to relapse in patients with bipolar disorder

Patients with frequently relapsing bipolar disorder had a significant delay in the time to an initial relapse when risperidone long-acting injection (RLAI) was combined with standard treatment, according to a new study. The study compared patients who received RLAI and standard treatment to those who received standard treatment combined with placebo.

4 Feb 2008

Antipsychotic News and Research

Nurse care for schizophrenia patients

Antipsychotic drugs increase risk of developing pneumonia in elderly

Treatment with an anti-psychotic drug found to cause changes in metabolism earlier than expected

Aripiprazole has potential for treating alcohol dependence

Restrictive drug policies often cause schizophrenic patients to discontinue medication

Researchers may have found test for depression

New discovery could change future diagnosis and therapy of depression

Genetic variations increase risk of anxiety disorders

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

Abilify (aripiprazole) approved for acute treatment of bipolar I disorder in adolescents

Lilly knocked back by FDA on Zyprexa for schizophrenia treatment

Treatment of children and adolescents with schizophrenia

Discovery of new receptor complex in brain - better understanding of how hallucinations occur

Siblings of schizophrenia patients display subtle shape abnormalities in brain

Study suggests Risperidone long-acting injection combined with standard treatment helped delay time to relapse in patients with bipolar disorder

U.S. mental health survey of people with schizophrenia and providers

Selective restraints and reduced medication could reduce nursing home falls

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity

Drug metformin and lifestyle changes can help treat weight gain induced by antipsychotic drugs

Placebo better than antipsychotic drugs for treating aggression in the intellectually disabled

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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